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Regulatory Operations Senior Manager

10-12 years
Not Disclosed
10 Sept. 18, 2025
Job Description
Job Type: Full Time Education: B.Sc/M.Sc/M.Pharma/B.Pharma/Life Sciences Skills: Causality Assessment, Clinical SAS Programming, Communication Skills, CPC Certified, GCP guidelines, ICD-10 CM Codes, CPT-Codes, HCPCS Codes, ICD-10 CM, CPT, HCPCS Coding, ICH guidelines, ICSR Case Processing, Interpersonal Skill, Labelling Assessment, MedDRA Coding, Medical Billing, Medical Coding, Medical Terminology, Narrative Writing

Job Title: Senior Manager – Regulatory Operations
Location: Princeton, NJ, USA
Department: Regulatory Affairs
Reports To: Senior Manager
Employment Type: Full-Time

Educational Qualification:

  • Bachelor’s Degree (Life Sciences or related field preferred)


Job Purpose:

Lead and execute regulatory operations strategies for novel drug development, ensuring compliance with global regulatory requirements, overseeing submissions, and aligning regulatory strategy with business and development objectives.


Key Responsibilities:

Regulatory Strategy & Planning:

  • Develop and execute novel drug regulatory strategies.

  • Provide high-level review of client programs and develop strategic plans for clinical, analytical, and process development.

  • Ensure compliance with ICH guidelines and all local country regulatory requirements.

  • Strategize EU expansion, including MAA planning, submission types (DCP, CP, NP, MRP), country selection, and EU QPPV office setup.

Operations & Project Management:

  • Manage day-to-day regulatory operations using project management and planning tools; create and maintain detailed project timelines.

  • Initiate, author, and/or collaborate on SOPs, work instructions, and workflows for regulatory operations, e.g., eCTD submissions, Investigational and Marketing Applications, and post-marketing compliance.

  • Work closely with development teams to ensure alignment of overall regulatory, CMC, and labeling strategies for pharmaceutical/biological products.

Regulatory Submissions & Liaison:

  • Author clear and concise regulatory documents (CMC authoring) and oversee all submission documents and messaging.

  • Serve as the primary point of contact between the company and regulatory agencies, acting as regulatory liaison.

Governance & Compliance:

  • Maintain awareness of global submission standards, including FDA, HC, EMA, ICH, eCTD, and industry trends for dossier preparation (IND/CTA/NDA/MAA/NDA).

  • Apply regulatory information management concepts and tools to prioritize operations supporting all business areas.


Required Skills & Competencies:

  • 10–15 years’ experience in regulated life sciences environments.

  • Strong project management and interpersonal skills.

  • Experience in defining organizational strategy, process and change management, KPIs and metrics, and resource forecasting.

  • Extensive knowledge of global submission standards, eCTD publishing systems, TRS toolbox, and regulatory change management.

Desirable Skills & Experience:

  • Knowledge of RoW markets and medical device regulations.

  • Business development skills.

  • Sound understanding of regulatory operations tools and concepts.