Therapeutic Area Head – Cardio Metabolic and Intensive Care
Updated: February 3, 2026
Location: London, United Kingdom
Job ID: 25104699-OTHLOC-3526-2DR
Employment Type: Full-Time | Executive Leadership
About the Role
Syneos Health is seeking an accomplished Therapeutic Area Head – Cardio Metabolic and Intensive Care to provide strategic, scientific, and operational leadership across a global portfolio of complex clinical development programs. This senior executive role oversees studies spanning Cardiology, Metabolic Disorders, and Intensive Care, ensuring delivery excellence, financial performance, innovation, and long-term client partnerships.
As a key member of the Global Project Management Leadership Team, this leader will shape therapeutic delivery strategy, ensure scientific rigor, and strengthen Syneos Health’s position as a global leader in Cardio Metabolic and Critical Care research.
Key Responsibilities
Strategic & Organizational Leadership
Define and execute the global delivery strategy for Cardio Metabolic and Intensive Care programs, aligning clinical execution with corporate objectives and client expectations.
Anticipate emerging scientific, regulatory, and market trends to position Syneos Health as the preferred CRO partner in these therapeutic areas.
Drive operational excellence, scalability, and modernization across clinical development platforms.
Partner with senior enterprise leaders to align delivery models with long-term growth priorities.
Scientific Authority & External Influence
Maintain deep scientific expertise across cardiovascular, metabolic, and intensive care indications.
Serve as a trusted scientific and strategic advisor to client C-suite leaders, regulatory bodies, and industry partners.
Represent Syneos Health at global scientific and industry forums, enhancing credibility and thought leadership.
Integrate evidence-based insights to shape client development strategies and partnerships.
Therapeutic Portfolio Oversight
Provide executive oversight across all phases of Cardio Metabolic and Intensive Care clinical programs.
Ensure delivery performance, proactive risk management, and consistent client satisfaction.
Establish governance frameworks for performance tracking, escalation management, and continuous improvement.
Collaborate cross-functionally with operational, scientific, quality, and technology leaders to drive innovation in clinical delivery.
Executive Client Management & Business Development
Act as senior executive sponsor for strategic Cardio Metabolic and Intensive Care clients.
Support business development initiatives, including bid defenses, RFIs, and strategic growth engagements.
Partner with Business Development and functional leaders to expand portfolio value and long-term partnerships.
Coach senior leaders to deliver high-impact client presentations and engagements.
Financial & Operational Accountability
Own financial performance of the therapeutic area, including forecasting, budgeting, and profitability.
Optimize resource utilization and strengthen portfolio economics through data-driven decision making.
Partner with Finance and Operations to ensure sustainable cost structures and scalable growth models.
Talent Development & Culture
Lead, mentor, and develop global leadership teams (VP and below), fostering accountability and high performance.
Build succession pipelines and future leadership capabilities within the therapeutic area.
Promote a culture of inclusion, collaboration, and continuous improvement across global teams.
Quality, Compliance & Continuous Improvement
Ensure compliance with ICH/GCP, regulatory requirements, and internal quality systems.
Support inspection readiness and consistent quality execution across global programs.
Lead process improvement initiatives to enhance efficiency, scalability, and client satisfaction.
Required Qualifications & Experience
Advanced degree in Life Sciences, Medicine, Pharmacy, or a related discipline (MS, PharmD, MD, or equivalent required; PhD preferred).
Minimum 15+ years of experience in clinical research, clinical operations, or project management within CRO, pharmaceutical, or biotechnology organizations.
Extensive leadership experience overseeing complex clinical development programs in cardiology, metabolic disorders, and/or intensive care.
Proven ability to manage large, global portfolios and lead multi-layered executive teams.
Strong business and financial acumen, including P&L ownership, budgeting, and forecasting.
In-depth knowledge of drug development, global regulatory requirements, and GCP/ICH guidelines.
Exceptional executive presence with demonstrated ability to influence C-suite stakeholders and senior clients.
Track record of driving innovation, transformation, and operational excellence at scale.
Willingness to travel approximately 30–35%.
Compensation & Benefits
Salary Range: USD 245,600 – 454,300 (commensurate with experience and qualifications).
Competitive executive benefits package, which may include company car or allowance, medical, dental, and vision coverage, retirement savings with employer match, employee stock purchase plan, performance-based incentives, and flexible paid time off.
Why Syneos Health
Syneos Health is a fully integrated biopharmaceutical solutions organization operating across 110 countries with over 29,000 professionals worldwide. We support the majority of novel FDA-approved and EMA-authorized therapies, partnering with sponsors to accelerate development and improve patient outcomes globally.
Our culture is built on inclusion, scientific excellence, and operational rigor—empowering leaders to drive meaningful impact across global clinical development programs.
Additional Information
Responsibilities listed are not exhaustive; additional duties may be assigned as business needs evolve.
Equivalent combinations of education, skills, and experience will be considered.
Syneos Health is an equal opportunity employer and complies with all applicable employment and accessibility laws.
Job Summary:
This role is suited for a senior executive clinical research leader with deep expertise in Cardio Metabolic and Intensive Care, capable of driving global portfolio performance, scientific leadership, and sustainable growth within a leading CRO environment.
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