Therapeutic Area Head, General Medicine

Syneos Health

15+ years

preferred by company

London United Kingdom

10 Feb. 6, 2026

Job Description

Job Type: Full Time Education: B.Sc./ M.Sc./ M.Pharm/ B.Pharm/ Life Sciences Skills: Causality Assessment, Clinical SAS Programming, Communication Skills, CPC Certified, GCP guidelines, ICD-10 CM Codes, CPT-Codes, HCPCS Codes, ICD-10 CM, CPT, HCPCS Coding, ICH guidelines, ICSR Case Processing, Interpersonal Skill, Labelling Assessment, MedDRA Coding, Medical Billing, Medical Coding, Medical Terminology, Narrative Writing, Research & Development, Technical Skill, Triage of ICSRs, WHO DD Coding

Therapeutic Area Head – General Medicine

Updated: February 3, 2026
Location: London, United Kingdom
Job ID: 25105080-OTHLOC-3526-2DR
Employment Type: Full-Time

About the Role

Syneos Health is seeking a seasoned Therapeutic Area Head – General Medicine to provide strategic, scientific, and operational leadership across a global portfolio spanning Infectious Disease, Vaccines, Respiratory, Cell & Gene Therapy (CGT), and select Medical Device & Diagnostics (MD&D) programs. This executive role is pivotal in advancing clinical delivery excellence, shaping therapeutic strategy, modernizing operational capabilities, and driving high-value growth aligned with corporate goals.

As a senior member of the Global Project Management Leadership Team, the Therapeutic Area Head will serve as a scientific authority, operational strategist, and key partner to clients, industry stakeholders, and internal teams, ensuring Syneos Health remains the partner of choice in General Medicine research.

Key Responsibilities

Strategic Leadership

Develop and execute the strategic vision for General Medicine delivery, ensuring alignment with corporate priorities and global growth strategies.
Transform go-to-market strategies, including modernization of global capabilities, TCOE-based collateral, and conference engagement.
Monitor emerging scientific, regulatory, and competitive trends to position Syneos Health as a preferred partner.
Collaborate with senior executives to establish scalable, cohesive operational models supporting portfolio growth.

Scientific Authority & External Influence

Maintain deep scientific expertise across infectious disease, immunology, respiratory medicine, vaccines, advanced therapies, and MD&D.
Serve as a recognized advisor to senior clients, regulatory agencies, and external partners.
Represent Syneos Health at international scientific forums, enhancing thought leadership and global visibility.
Integrate scientific, commercial, and development insights to shape client strategies.

Therapeutic Portfolio Oversight

Provide executive oversight for all General Medicine projects across phases I–IV, ensuring operational excellence, risk mitigation, and client satisfaction.
Guide portfolio prioritization and resource alignment to support growth trajectories in vaccines, ID, respiratory innovation, CGT, and MD&D.
Establish governance to monitor delivery performance and drive continuous improvement.
Collaborate with operational and scientific teams to modernize capabilities, including analytics, AI-enabled risk management, and evidence-based frameworks.

Executive Client Management & Business Development

Serve as senior liaison for strategic General Medicine clients.
Support business development initiatives, including proposals, bid defenses, and strategic partnerships.
Build long-term client relationships reinforcing Syneos Health’s differentiated scientific and operational capabilities.

Financial & Operational Leadership

Maintain accountability for financial performance, including forecasting, profitability, and resource optimization.
Drive operational efficiency, predictability, and data-driven decision making.
Partner with Finance and Operations to ensure scalable business models supporting global growth.

Organizational Leadership & Talent Development

Lead and mentor global leadership teams, fostering collaboration, accountability, and high performance.
Develop succession pipelines for scientific, operational, and executive roles.
Promote an inclusive culture that drives innovation across therapeutic and geographic lines.

Quality, Compliance & Continuous Improvement

Ensure compliance with ICH/GCP, regulatory standards, and internal quality systems.
Lead initiatives to modernize General Medicine capabilities and optimize operational infrastructure.
Drive continuous improvement to enhance delivery scalability, client satisfaction, and operational resilience.

Required Qualifications & Experience

Advanced degree in Life Sciences, Medicine, Pharmacy, or related scientific discipline (MS, PharmD, MD, PhD, or equivalent).
15+ years of experience in clinical research, project management, or clinical operations within CRO, pharmaceutical, or biotech settings.
Proven executive leadership in managing complex clinical development programs in infectious disease, vaccines, respiratory, or advanced therapies; experience in MD&D preferred.
Demonstrated ability to lead large, global portfolios and multi-layered leadership teams.
Strong business acumen with experience in forecasting, financial management, and therapeutic growth strategy.
Expertise in drug development, global regulatory expectations, and evolving scientific landscapes.
Exceptional executive presence with proven ability to influence C-suite stakeholders, clients, and internal leaders.
Track record of driving innovation, transformation, and modernization within clinical operations.
Willingness to travel approximately 30–35%.

Compensation & Benefits

Salary Range: $245,600 – $454,300 (USD), dependent on experience and qualifications.
Comprehensive benefits including medical, dental, vision, company match 401k, Employee Stock Purchase Plan, performance-based bonus eligibility, flexible paid time off, and more.

Why Syneos Health

Syneos Health is a fully integrated biopharmaceutical solutions organization, working across 110 countries with over 29,000 employees. Our teams collaborate to deliver innovative therapies and accelerate patient access worldwide.

We foster a Total Self culture, supporting diversity, equity, and inclusion while encouraging employees to bring their authentic selves to work. Professional development, mentorship, and a collaborative environment are central to our approach.

Additional Information

Responsibilities listed are not exhaustive; additional tasks may be assigned.
Equivalent combinations of education, skills, and experience will be considered.
Syneos Health is committed to equal employment opportunity and compliance with applicable labor laws and regulations.

Job Summary:
This role is ideal for a senior executive leader in General Medicine with extensive experience in global clinical research, capable of driving portfolio growth, operational excellence, and scientific leadership at scale.

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Therapeutic Area Head, General Medicine

Job Description

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