Senior Medical Scientist – Protocol Design & Study Execution (Sponsor-Dedicated)
Updated: February 3, 2026
Location: London, United Kingdom
Job ID: 25105453-OTHLOC-3526-2DR
Employment Type: Full-Time | Sponsor-Dedicated Role
About Syneos Health
Syneos Health® is a globally recognized, fully integrated biopharmaceutical solutions organization focused on accelerating clinical development and improving patient outcomes. By combining clinical development, medical affairs, and commercial expertise, Syneos Health partners with biopharmaceutical and biotech organizations to deliver high-quality, data-driven clinical research solutions across the product lifecycle.
With a global workforce of more than 29,000 professionals across 110 countries, Syneos Health is committed to scientific excellence, operational efficiency, and a collaborative, inclusive culture.
Role Overview
The Senior Medical Scientist – Protocol Design & Study Execution is a sponsor-dedicated clinical science role responsible for providing scientific and operational leadership across early- and late-phase clinical studies. This position partners closely with Medical Directors and cross-functional teams to ensure scientifically robust study design, high-quality execution, and regulatory-compliant delivery of clinical trials.
The role focuses on protocol development, study oversight, data review, and regulatory documentation while supporting consistent execution across multinational clinical programs.
Key Responsibilities
Clinical & Scientific Leadership
Support or lead clinical studies of varying complexity across therapeutic areas
Contribute to protocol design, development, and authoring in collaboration with Medical Directors
Ensure scientific integrity, data quality, patient safety, and regulatory compliance throughout study execution
Provide clinical and scientific input into study plans, amendments, reports, and publications
Study Execution & Oversight
Oversee tactical execution of assigned studies, including vendor coordination and study planning
Monitor study progress, identify risks or operational challenges, and implement mitigation strategies
Review clinical data and safety outputs to support ongoing study assessments
Ensure adherence to Good Clinical Practice (GCP), SOPs, and global regulatory requirements
Cross-Functional & Global Collaboration
Collaborate with global, cross-functional teams including Clinical Operations, Data Management, Biostatistics, and Regulatory Affairs
Participate in cross-program discussions to promote scientific and operational consistency across studies
Support engagement with external vendors, partners, and stakeholders
Required Qualifications & Experience
Bachelor’s degree in Life Sciences or a health-related field with minimum 5 years of clinical research experience
OR Master’s/MBA with 3+ years of experience
OR PharmD/PhD with 2+ years of experience
OR MD/DO with 1+ year of experience
Prior experience in a Clinical Scientist, Medical Scientist, or equivalent role
Demonstrated experience working on multinational clinical studies and cross-functional teams
Practical experience in epidemiologic and/or observational study design and conduct
Proven ability to independently manage multiple studies and competing priorities
Strong understanding of clinical trial processes, monitoring, regulatory operations, and GCP
Hands-on experience authoring clinical study protocols and study-related documentation
Working knowledge of statistics, clinical data analysis, and vendor management
Key Skills & Competencies
Excellent written and verbal English communication skills
Strong scientific writing and documentation capabilities
Ability to collaborate effectively in a global, matrixed environment
Strong analytical, organizational, and problem-solving skills
High attention to detail with a commitment to quality and compliance
Why Join Syneos Health
Sponsor-dedicated role with direct involvement in high-impact clinical programs
Exposure to global, multi-region clinical trials and innovative therapies
Structured career development and scientific growth opportunities
Collaborative culture aligned with the Total Self philosophy
Opportunity to contribute to trials supporting both FDA and EMA approvals
Syneos Health at a Glance
Supported 94% of novel FDA-approved drugs in the past five years
Contributed to 95% of EMA-authorized products
Delivered 200+ studies across 73,000 sites involving 675,000+ trial participants globally
Equal Opportunity & Compliance Statement
This job description is not exhaustive and may be amended as business needs evolve. Syneos Health is an equal opportunity employer and complies with all applicable employment laws, including the EU Equality Directive and the Americans with Disabilities Act (ADA). Reasonable accommodations will be provided where required.
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