Therapeutic Area Head, General Medicine

Syneos Health

15 years

preferred by company

London United Kingdom

10 Feb. 6, 2026

Job Description

Job Type: Full Time Education: B.Sc./ M.Sc./ M.Pharm/ B.Pharm/ Life Sciences Skills: Causality Assessment, Clinical SAS Programming, Communication Skills, CPC Certified, GCP guidelines, ICD-10 CM Codes, CPT-Codes, HCPCS Codes, ICD-10 CM, CPT, HCPCS Coding, ICH guidelines, ICSR Case Processing, Interpersonal Skill, Labelling Assessment, MedDRA Coding, Medical Billing, Medical Coding, Medical Terminology, Narrative Writing, Research & Development, Technical Skill, Triage of ICSRs, WHO DD Coding

Therapeutic Area Head – General Medicine

Updated: February 3, 2026
Location: London, United Kingdom
Job ID: 25105080

About Syneos Health

Syneos Health® is a global, fully integrated biopharmaceutical solutions organization dedicated to accelerating the delivery of innovative therapies from development to commercialization. By combining clinical development, medical affairs, and commercial expertise, Syneos Health partners with life sciences companies worldwide to address complex market and patient needs. With more than 29,000 employees across 110 countries, the organization is recognized for its scientific leadership, operational excellence, and patient-centric approach.

Role Overview

The Therapeutic Area Head – General Medicine is a senior executive leadership role responsible for providing strategic, scientific, and operational oversight across a global General Medicine portfolio. This portfolio includes Infectious Disease, Vaccines, Respiratory, Cell & Gene Therapy (CGT), and selected Medical Device and Diagnostics (MD&D) programs.

Following the strategic separation of Cardiometabolic and Intensive Care, this role ensures focused leadership across therapeutic areas with the greatest growth potential and strategic importance to Syneos Health. As a key member of the Global Project Management Leadership Team, the role drives delivery excellence, portfolio expansion, and long-term value creation while positioning Syneos Health as a preferred partner in General Medicine clinical research.

Key Responsibilities

Strategic and Therapeutic Leadership

Define and execute the global strategy for General Medicine clinical delivery, aligned with corporate objectives and long-range growth plans.
Lead the evolution of go-to-market and delivery models, including modernization of Therapeutic Center of Excellence (TCOE) capabilities and global engagement strategies.
Monitor emerging scientific, regulatory, and competitive trends across infectious disease, vaccines, respiratory medicine, CGT, and MD&D to strengthen market positioning.
Partner with senior enterprise leaders to ensure scalable, efficient, and future-ready operating models.

Scientific Authority and External Engagement

Maintain deep scientific expertise across General Medicine therapeutic domains, including immunology, respiratory medicine, vaccines, and advanced therapies.
Serve as a trusted scientific and strategic advisor to senior clients, regulators, and industry stakeholders.
Represent Syneos Health at global scientific forums, conferences, and industry associations to enhance thought leadership and brand credibility.
Support client strategy development by integrating scientific evidence, commercial insights, and global regulatory considerations.

Global Portfolio Oversight

Provide executive oversight of General Medicine clinical programs across Phases I–IV, ensuring delivery excellence, quality, and client satisfaction.
Guide portfolio prioritization and resource allocation to support global growth initiatives across Europe, APAC, and other key regions.
Establish governance frameworks to track performance, manage risk, and drive continuous improvement across global delivery teams.
Collaborate with operations, data science, and technology leaders to modernize delivery through analytics, AI-enabled risk management, and evidence-based decision-making.

Client Leadership and Business Growth

Act as the senior executive sponsor for strategic General Medicine clients.
Partner with Business Development, Medical Affairs, and Operations to identify growth opportunities and strengthen client value propositions.
Support high-impact client engagements, including bid defenses, RFIs, and strategic partnerships.
Build and sustain long-term client relationships grounded in scientific credibility and operational excellence.

Financial and Operational Accountability

Own full financial accountability for the General Medicine portfolio, including forecasting, profitability, and resource optimization.
Drive operational efficiency and predictability through data-driven performance management.
Partner with Finance and Operations to ensure scalable business models that support sustained global growth.

Leadership, Talent, and Culture

Lead and mentor a global leadership team (Vice President level and below), fostering a high-performance, inclusive culture.
Develop talent pipelines and succession plans for future scientific and operational leaders.
Promote collaboration, accountability, and innovation across therapeutic and geographic boundaries.

Quality and Compliance

Ensure adherence to ICH/GCP guidelines, global regulatory requirements, and internal quality standards.
Partner with Quality leadership to maintain inspection readiness and consistent delivery quality.
Lead continuous improvement initiatives to enhance scalability, resilience, and client satisfaction.

Experience and Qualifications

Advanced degree required (MS, PharmD, MD, PhD, or equivalent) in Life Sciences, Medicine, Pharmacy, or a related scientific discipline.
Minimum 15 years of experience in clinical research, clinical operations, or project management within a CRO, pharmaceutical, or biotechnology organization.
Proven leadership experience overseeing complex global clinical development programs in infectious disease, vaccines, respiratory medicine, or advanced therapies; MD&D experience is advantageous.
Demonstrated ability to lead large, multi-regional portfolios and senior leadership teams.
Strong business acumen with experience in financial forecasting, portfolio management, and growth strategy.
Expert knowledge of drug development processes, GCP/ICH standards, and global regulatory environments.
Exceptional executive presence with the ability to influence C-suite stakeholders and senior clients.
Willingness to travel internationally as required (approximately 30–35%).

Compensation and Benefits

Syneos Health offers a competitive executive compensation package, including base salary, performance-based incentives, and comprehensive benefits. Salary range for this role is USD 245,600 – 454,300, with final compensation determined by experience, qualifications, and geographic location.

Why Join Syneos Health

At Syneos Health, employees are empowered to thrive professionally while making a meaningful impact on global healthcare. The organization fosters a collaborative, inclusive culture and provides opportunities to lead transformative clinical programs that improve patient outcomes worldwide.

Over the past five years, Syneos Health has supported the majority of novel FDA and EMA approvals, working across thousands of clinical sites and patient populations globally.a

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Therapeutic Area Head, General Medicine

Job Description

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