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Manager – Regulatory Affairs (Cmc)

5 years
Not Disclosed
10 Nov. 25, 2025
Job Description
Job Type: Full Time Remote Education: B.Sc./ M.Sc./ M.Pharm/ B.Pharm/ Life Sciences Skills: Causality Assessment, Clinical SAS Programming, Communication Skills, CPC Certified, GCP guidelines, ICD-10 CM Codes, CPT-Codes, HCPCS Codes, ICD-10 CM, CPT, HCPCS Coding, ICH guidelines, ICSR Case Processing, Interpersonal Skill, Labelling Assessment, MedDRA Coding, Medical Billing, Medical Coding, Medical Terminology, Narrative Writing, Research & Development, Technical Skill, Triage of ICSRs, WHO DD Coding

Manager – Regulatory Affairs (CMC)

Location: Remote, India
Job Type: Full-Time
Category: Clinical Research
Work Mode: Fully Remote

About the Role

A leading global contract research organization (CRO), supporting the PPD® clinical research portfolio, is seeking an experienced Manager – Regulatory Affairs (CMC). This role requires advanced regulatory expertise to support global CMC submissions, lifecycle management, regulatory strategy, and cross-functional collaboration for complex biopharmaceutical programs.

As a senior member of the Regulatory Affairs team, you will lead CMC authoring activities, guide regulatory strategy, ensure compliance, and provide technical oversight across global markets.


Key Responsibilities

CMC Documentation & Submissions

  • Lead authoring and preparation of CMC packages for global post-approval lifecycle submissions, including variations, renewals, annual reports, and responses to Health Authority requests.

  • Conduct global change control assessments and confirm CMC requirements for submissions such as variations, renewals, and tender applications.

  • Align with internal and external clients to gather technical information and ensure timelines are met.

  • Prepare high-quality regulatory packages for internal review and finalize for publishing and QC.

Regulatory Strategy & Compliance

  • Act as a subject matter expert (SME) providing regulatory strategy, risk assessment, and technical guidance for projects of moderate to high complexity.

  • Provide up-to-date regulatory intelligence on global CMC guidelines, legislation, and emerging requirements.

  • Ensure full compliance with organizational SOPs, regulatory standards, and quality processes.

Cross-Functional Collaboration

  • Support Health Authority and partner requests by providing accurate responses and technical clarification.

  • Engage in launch meetings, project team reviews, and cross-functional collaborations to support regulatory alignment.

  • Work closely with business development teams for pricing, proposals, and client presentations.

Project Oversight & Leadership

  • Manage budgeting, forecasting, and resource planning for regulatory projects.

  • Identify out-of-scope activities and initiate contract modification processes.

  • Provide leadership, mentorship, and training to junior regulatory team members.

  • Ensure high-quality performance and timely delivery of regulatory milestones.

System Updates & Documentation

  • Maintain and update internal systems including RIMS (e.g., Veeva RIMS), eDMS (e.g., Documentum), publishing platforms, and change management systems.

  • Provide accurate documentation and ensure data integrity across systems.


Required Qualifications

Education

  • Bachelor’s or Master’s degree in Life Sciences, Pharmacy, or related health sciences.

  • A specialized degree in Regulatory Affairs is advantageous.

Experience

  • Minimum 5 years of experience in the biotechnology or pharmaceutical industry.

  • At least 5 years of hands-on Regulatory Affairs CMC experience supporting global submissions.

  • Strong background in biologicals, vaccines, small molecules, gene therapy, or plasma-related products.

  • Proven understanding of global regulatory frameworks for major regions including US, EU, Japan, Switzerland, Australia, China, and RoW.

  • Demonstrated expertise in CMC authoring, technical evaluation, and regulatory compliance.

  • Sound knowledge of Good Manufacturing Practices (GMP) and related regulatory expectations.


Technical Skills

  • Proficiency with regulatory systems including:

    • RIMS (e.g., Veeva RIMS)

    • eDMS (e.g., Veeva, Documentum)

    • Change Management systems (e.g., Trackwise)

  • Strong command of Microsoft Office tools.


Core Competencies

  • Exceptional communication and presentation skills.

  • Strong project management, problem-solving, and planning capabilities.

  • Ability to build collaborative relationships with cross-functional teams and senior stakeholders.

  • High attention to detail with strong organizational follow-through.

  • Ability to work independently with sound technical judgment.

  • Comfortable working in a global, multicultural environment.

  • Fluency in English and local language.