Senior Director – Gene Therapy Medical Affairs
Location: Indianapolis, Indiana, USA
Category: Medical
Job Type: Full Time – Regular
Job ID: R-95063
About Lilly
Lilly is a global healthcare leader focused on discovering and delivering life-changing medicines, advancing disease understanding, and improving patient outcomes worldwide. The company is committed to scientific innovation, compassionate care, and community impact.
Role Overview
The Senior Director, Gene Therapy Medical Affairs will provide strategic and scientific leadership across Lilly’s gene therapy portfolio, including sensory disorders, rare diseases, and neurodegenerative conditions.
This leader will be the primary interface with key opinion leaders, treatment centers of excellence, and global experts, ensuring exceptional customer experiences and supporting gene therapy adoption.
The role requires identifying unmet medical needs, reducing diagnostic barriers, and developing comprehensive medical strategies, while collaborating internally with clinical, commercial, regulatory, legal, compliance, and other functions.
Key Responsibilities
1. Scientific & Strategic Leadership
Serve as the scientific expert for gene therapy and related therapeutic areas.
Stay updated on advances in genetics, rare diseases, and gene therapy science.
Lead cross-functional collaboration to shape launch strategies and medical plans.
2. KOL & Stakeholder Engagement
Build and maintain strong relationships with:
Key opinion leaders (KOLs)
External scientific experts
Patient advocacy leaders
Identify scientific trends, unmet needs, and external opportunities.
Provide accurate scientific and medical education to external stakeholders.
3. Gene Therapy Centers of Excellence Support
Provide scientific training and education to treatment center staff.
Help remove site-specific barriers to gene therapy administration.
Support center readiness and address medical/scientific challenges.
4. Field Insights
Collect, interpret, and communicate actionable clinical insights from the field.
Share insights to shape medical, commercial, and patient-focused strategies.
5. Education & Communication
Develop and review scientific content for internal and external presentations.
Educate healthcare professionals, patients, and families on genetic testing and gene therapy.
Contribute to medical education initiatives and internal knowledge building.
6. Clinical Support
Support clinical study teams by driving trial awareness.
Provide patient and healthcare professional insights to improve trial execution.
7. Compliance & Governance
Ensure strict compliance with all internal/external regulations.
Demonstrate sound judgment and ethical decision-making at all times.
Basic Qualifications
Education & Experience
One of the following:
Option 1:
PharmD or PhD in a medically or scientifically related field
8+ years of relevant industry experience
Option 2:
Master’s degree in a medically/scientifically related field
10+ years of industry experience in relevant therapeutic areas
Required Experience
Medical Affairs or Patient Advocacy experience
Background in genetics, gene therapy, or rare diseases
Additional Preferences
High learning agility, with the ability to absorb and communicate complex science.
Strong self-management and multitasking ability.
Advanced presentation and computer proficiency (including literature research).
Strong interpersonal skills with proven networking and relationship-building ability.
Experience handling complex scientific customer questions.
Field-based work experience is highly valued.
Ability to travel ~40%, including weekends and potential international travel.
Compensation & Benefits
Salary Range
$154,500 – $226,600
(Actual compensation depends on experience, skills, and location.)
Eligible Benefits Include:
Annual company bonus
401(k) participation & pension
Medical, dental, vision, and prescription benefits
Flexible spending accounts
Life insurance and death benefits
Vacation and leave programs
Employee assistance programs, wellness benefits, activities & clubs
Lilly may modify or terminate benefits at its discretion.
Diversity, Equity & Inclusion
Lilly is an Equal Employment Opportunity (EEO) employer and prohibits discrimination based on:
Age, race, sex, religion, gender identity, gender expression, sexual orientation, genetics, disability, veteran status, ancestry, or any legally protected status.
Employee Resource Groups (ERGs) include:
Africa, Middle East, Central Asia Network
Black Employees at Lilly
Chinese Culture Network
JILN (Japanese International Leadership Network)
Lilly India Network
OLA (Organization of Latinx at Lilly)
PRIDE (LGBTQ+ Allies)
Veterans Leadership Network
WILL (Women’s Initiative for Leading at Lilly)
enAble (for employees with disabilities)
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