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Senior Research Associate

2-3 years
Not Disclosed
10 Jan. 28, 2025
Job Description
Job Type: Full Time Education: B.Sc,M.Sc,B.Pharma,M.Pharma,LifeScience Graduates Skills: Causality Assessment, Clinical SAS Programming, Communication Skills, CPC Certified, GCP guidelines, ICD-10 CM Codes, CPT-Codes, HCPCS Codes, ICD-10 CM, CPT, HCPCS Coding, ICH guidelines, ICSR Case Processing, Interpersonal Skill, Labelling Assessment, MedDRA Coding, Medical Billing, Medical Coding, Medical Terminology, Narrative Writing, Research & Development, Technical Skill, Triage of ICSRs, WHO DD Coding

Job Title: In Vivo PK Scientist
Date: 22 Jan 2025
Job Location: Bengaluru


About Syngene

Syngene International Ltd. (BSE: 539268, NSE: SYNGENE) is an innovation-driven contract research, development, and manufacturing organization offering integrated scientific services across the entire product lifecycle—from early discovery to commercial supply. At Syngene, safety is at the core of our operations, with a commitment to adhering to safety guidelines, procedures, and SOPs to ensure the well-being of our team and the integrity of our work.

For more information, visit www.syngeneintl.com.


Role Overview

The In Vivo PK Scientist will be responsible for conducting in vivo pharmacokinetic studies in rodents, specifically focusing on the collection of various biological samples, surgical procedures, and data analysis to support pharmacokinetics and toxicology studies. The individual will work within a dynamic team environment while adhering to safety guidelines and regulations.


Core Purpose of the Role

  • Conduct in vivo pharmacokinetic studies in rodents.
  • Manage and document experimental data in lab notebooks and through compound management systems.
  • Ensure adherence to safety protocols and environmental, health, and safety (EHS) measures in the workplace.

Key Responsibilities

Pharmacokinetic Studies and Surgical Procedures:

  • Perform pharmacokinetic studies in rodents, including cannulation procedures (e.g., jugular, femoral, portal vein) and chronic bile duct cannulations.
  • Collect vital organs during tissue distribution studies and various biological fluids (e.g., cerebrospinal fluid, bile, urine, synovial fluid) for analysis.
  • Understand and manage formulations used in pharmacokinetic, efficacy, and toxicity studies.

Data Management and Documentation:

  • Document all experimental data in lab notebooks, following Syngene’s documentation standards.
  • Utilize data analysis tools such as Phoenix WinNonlin for pharmacokinetic data analysis.
  • Manage compound inventory and ensure proper tracking.

Safety and Compliance:

  • Follow all environment, health, and safety (EHS) protocols to ensure the safety of yourself, team members, and the laboratory environment.
  • Ensure that EHS measures are trained and adhered to within the team.
  • Report any safety incidents or deviations promptly.

Educational Qualifications and Experience

  • Education:

    • M. Pharm or M.V. Sc. in Pharmacology or Toxicology.
  • Experience:

    • 2-3 years of post-qualification experience in conducting in vivo pharmacokinetic studies.

Skills and Capabilities

Technical Skills:

  • Expertise in surgical procedures (e.g., cannulation of jugular, femoral, portal vein) in rodents.
  • Experience with chronic bile duct cannulations and tissue distribution studies.
  • Proficient in the collection of biological fluids (e.g., CSF, bile, urine) for pharmacokinetic studies.
  • Knowledge of pharmacokinetic data analysis using Phoenix WinNonlin and other relevant software.
  • Understanding of formulations used in pharmacokinetics and toxicology studies.
  • Knowledge of regulatory guidelines for drug metabolism and pharmacokinetics is desirable.

Behavioral Skills:

  • Strong communication skills, with the ability to effectively collaborate in a team environment.
  • Enthusiastic, committed, and able to work with deadlines.
  • Ability to troubleshoot and think creatively to solve problems.
  • Good interpersonal skills and the ability to work professionally with colleagues.

Equal Opportunity Employer

Syngene is an equal opportunity employer and is committed to providing equal employment opportunities to all individuals regardless of age, color, national origin, citizenship status, disability, race, religion, gender, sexual orientation, gender identity, genetic information, marital status, veteran status, or other protected characteristics under applicable laws. Reasonable accommodations will be provided for qualified individuals with disabilities.

For more details, visit www.syngeneintl.com.