Global Development Product Lead – Executive Director (Oncology)
Locations:
United States – California, La Jolla
United States – Massachusetts, Cambridge
United States – Washington, Bothell
United States – California, South San Francisco
United States – New York, New York City
Employment Type: Full-Time
Posted: 20 Days Ago
Job Requisition ID: 4950064
Position Overview:
Pfizer is seeking a highly experienced Global Development Product Lead (Executive Director) to lead multiple oncology product teams across early-stage development programs. This role is responsible for driving cross-functional strategy from pre-clinical candidate nomination (CAN) through Phase 1-2 clinical development and proof-of-concept (POC) stages. The role requires a strategic leader capable of aligning scientific, clinical, and operational objectives to deliver successful development outcomes for oncology assets.
This position is ideal for a senior oncology professional with ≥10 years of industry experience in drug development, proven leadership in early clinical development, and the ability to influence complex, matrixed teams.
Key Responsibilities:
Strategic Leadership & Program Oversight
Lead 2-4 global oncology product teams, overseeing early clinical development assets from first-in-human studies to proof-of-concept.
Develop and execute integrated cross-functional product strategies, addressing near-term technical uncertainties and ensuring alignment with pivotal development and commercialization plans.
Identify program risks and implement mitigation strategies to ensure timely delivery of milestones within budget.
Collaborate with co-development partners to deliver shared global product strategies when applicable.
Oversee development of clinical protocols, amendments, investigator brochures, clinical study reports, statistical analysis plans, and regulatory submissions.
Cross-Functional Collaboration
Partner with clinicians, statisticians, translational biologists, regulatory specialists, and clinical pharmacologists to advance development programs.
Drive PK-guided dose escalation strategies, early combination approaches, and emerging innovations in oncology clinical trials.
Coordinate with external networks, key opinion leaders (KOLs), and advisory boards to gather feedback and integrate insights into development plans.
Contribute to translational oncology and precision medicine strategies to accelerate the transition from preclinical research to clinical candidates.
Scientific & Clinical Expertise
Provide scientific leadership and oversight on clinical and preclinical programs.
Ensure high-quality interpretation and reporting of efficacy, pharmacology, and safety data from early development studies.
Support manuscripts, abstracts, presentations, and advisory board discussions to communicate scientific findings effectively.
Lead innovations in early clinical development, integrating translational research and biomarker strategies to optimize program success.
Team Leadership & Development
Inspire and guide cross-functional teams in a matrixed environment.
Mentor early-stage clinical scientists, fostering collaboration, accountability, and high-performance culture.
Build strong relationships with internal leadership, external partners, and investigators to drive alignment and execution.
Promote organizational excellence, trust, transparency, and team cohesion while ensuring focus on patient-centric outcomes.
Minimum Qualifications:
MD or MD-PhD with ≥10 years of experience in oncology drug development, including early-phase clinical research.
Board certification in oncology preferred.
Extensive leadership experience in clinical, translational, or basic biomedical research relevant to drug development.
Proven track record of scientific productivity (publications, abstracts, presentations).
Strong scientific writing, communication, and executive presentation skills.
Ability to influence cross-functional teams and defend clinical strategies at governance meetings.
Experience navigating fast-paced, dynamic environments with multiple stakeholders.
Preferred Qualifications:
Demonstrated expertise in translational oncology, biomarker-driven clinical development, or precision medicine strategies.
Experience managing multiple global early development programs concurrently.
Demonstrated success in mentoring and leading cross-functional teams within matrix organizations.
Strong global mindset with the ability to work effectively across cultures, geographies, and teams.
Work Arrangement:
Hybrid role; requires ~2.5 days onsite per week with commuting proximity to office locations.
Compensation & Benefits:
Annual base salary: $295,900 – $478,800
Eligible for Pfizer Global Performance Plan (30% bonus target) and share-based long-term incentive programs.
Comprehensive benefits including 401(k) with company match, paid leave, parental leave, and medical, dental, and vision coverage.
Why Join Pfizer:
This role offers the opportunity to lead transformative early oncology programs, influence global product strategy, and work with world-class scientific teams to deliver life-changing therapies for patients with cancer.
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Siliguri |Illinois :
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