Instagram
youtube
Facebook

Senior Director, Global Regulatory Affairs Cmc – Synthetic Molecules

3-10 years
$162,000 – $237,600 annually.
10 April 28, 2025
Job Description
Job Type: Full Time Education: B.Sc./M.Sc/B.Pharm/M.Pharm/Life Science Skills: Causality Assessment, Clinical SAS Programming, Communication Skills, CPC Certified, GCP guidelines, ICD-10 CM Codes, CPT-Codes, HCPCS Codes, ICD-10 CM, CPT, HCPCS Coding, ICH guidelines, ICSR Case Processing, Interpersonal Skill, Labelling Assessment, MedDRA Coding, Medical Billing, Medical Coding, Medical Terminology, Narrative Writing, Research & Development, Technical Skill, Triage of ICSRs, WHO DD Coding

 

Job Title

Senior Director, Global Regulatory Affairs CMC – Synthetic Molecules

Location

Indianapolis, Indiana, United States

Company

Eli Lilly and Company

Category

Research & Development

Job Type

Full Time | Regular

Job ID

R-82502

Position Summary

Eli Lilly is seeking a Senior Director for Global Regulatory Affairs CMC (GRA-CMC) to lead regulatory activities for global submissions related to synthetic molecules. This individual will manage the regulatory strategy for development and commercial products, supervise personnel, ensure on-time regulatory submission deliveries, and foster continuous improvement within the GRA-CMC organization. The Senior Director will provide scientific leadership and influence internal and external stakeholders while ensuring compliance with global CMC regulatory requirements.

Key Responsibilities

People Excellence - Supervision of Personnel:

  • Ensure staff have the necessary qualifications and align with leadership expectations.

  • Oversee recruitment and performance management for the team.

  • Develop and implement training curricula, ensuring appropriate resource allocation for projects.

Technical and Regulatory Functional Excellence:

  • Lead regulatory strategies and ensure they integrate scientific and technical principles.

  • Oversee preparation and finalization of CMC documents for global regulatory submissions (CTAs, MAAs, post-approval supplements).

  • Maintain knowledge of global CMC regulatory requirements and provide expertise to the team.

Oversight of CMC Project Deliverables:

  • Approve regulatory strategies for global CMC development and manufacturing changes.

  • Ensure on-time delivery of regulatory documents and manage submissions to health authorities.

  • Provide regulatory leadership and communicate strategies across teams to ensure compliance.

Internal and External Influence:

  • Mentor and influence internal teams, including cross-functional areas.

  • Participate in industry technical organizations and regulatory bodies to shape the external environment.

  • Influence internal governance committees and ensure departmental objectives are met.

Department Communications:

  • Stay informed of GRA initiatives and communicate information to the department.

  • Address and communicate issues to upper management as necessary.

Operational Excellence and Process Management:

  • Collaborate with other Senior Directors to evaluate and improve internal processes.

  • Ensure adherence to the Regulatory Quality System (RQS) and document key business practices.

Education Requirements

  • BS, MS, or PhD in Chemistry, Biology, Engineering, or a closely related science.

  • 10+ years of experience in CMC development and/or technical support for commercial products.

  • 3+ years of demonstrated team leadership experience.

  • Proven expertise in drug development, API, Drug Product, or Analytical areas.

Additional Skills/Preferences

  • In-depth knowledge of CMC regulatory experience.

  • Experience in synthetic molecule portfolio regulatory affairs.

  • Strong leadership, communication, and mentoring skills.

  • Familiarity with global regulatory processes and health authority interactions.

Compensation

  • Anticipated Salary Range: $162,000 – $237,600 annually.

  • Eligible for company bonus program (based on company and individual performance).

Benefits

  • 401(k) plan and pension

  • Vacation and paid time off

  • Medical, dental, vision, and prescription drug benefits

  • Flexible spending accounts (healthcare, dependent care)

  • Life insurance and death benefits

  • Wellness programs (EAP, fitness benefits, clubs and activities)

  • Other leave of absence benefits

Travel

  • 10-15% travel required.

On-Site Position

  • Located at Lilly Corporate Center in Indianapolis, Indiana.

Equal Opportunity Employer

Lilly is an equal opportunity employer dedicated to diversity and inclusion.

Employee Resource Groups (ERGs)

Includes groups such as Black Employees at Lilly, Organization of Latinx at Lilly (OLA), Lilly India Network, PRIDE (LGBTQ+ Allies), Women’s Initiative for Leading at Lilly (WILL), and others.

Accommodation

Applicants needing accommodations during the application process can request assistance via the Accommodation Request Form.