Scientific Associate Director, Gi, Inflammation, & Neuroscience, In Vitro Pharmacology

15+ years

149,100.00 - 234,300.00

Boston

10 Dec. 31, 2024

Job Description

Job Type: Full Time Education: PHD/MS/BS Skills: Causality Assessment, Clinical SAS Programming, Communication Skills, CPC Certified, GCP guidelines, ICD-10 CM Codes, CPT-Codes, HCPCS Codes, ICD-10 CM, CPT, HCPCS Coding, ICH guidelines, ICSR Case Processing, Interpersonal Skill, Labelling Assessment, MedDRA Coding, Medical Billing, Medical Coding, Medical Terminology, Narrative Writing, Research & Development, Technical Skill, Triage of ICSRs, WHO DD Coding

The job description you provided is for an Associate Director, In Vitro Pharmacology at Takeda in Boston, Massachusetts. This position is within Takeda's Global Biologics (GB) division, which focuses on advancing biologic therapeutics for oncology, gastroenterology (GI), inflammation, and neuroscience. Below is a summary of the key details:

Position Overview:

The Associate Director, In Vitro Pharmacology will lead a team responsible for designing and optimizing in vitro assays to evaluate biologic therapies targeting GI diseases, inflammation, and neurological disorders. This role involves applying state-of-the-art technologies to assess therapeutic candidates, managing complex scientific projects, and contributing to the strategic objectives of Takeda's biologics discovery programs.

Key Responsibilities:

Functional Leadership:
- Lead the design, development, and execution of in vitro pharmacology assays to evaluate the biological activity and efficacy of biologic therapies.
- Use advanced technologies (e.g., cell-based assays, 3D organoid models) to assess inflammatory pathways, neuronal signaling, and gut-brain axis interactions.
- Innovate and stay current with scientific advancements to improve therapeutic candidate evaluation.
Program Leadership:
- Spearhead biologics discovery programs in GI, inflammation, and neuroscience from lead identification to preclinical development.
- Oversee screening and profiling of biologic candidates in relevant in vitro models (e.g., inflammation assays, immune cell-based assays, neuronal models, GI organoid systems).
- Conduct mechanism-of-action studies to elucidate therapeutic activity, focusing on immune cell activation, neuronal signaling, and inflammatory pathways.
Cross-Functional Collaboration:
- Collaborate with biologics engineering, translational scientists, preclinical development teams, and other departments to align research efforts with strategic goals.
- Contribute to regulatory documents such as study reports and INDs to support therapeutic advancement.
Mentoring and Team Development:
- Mentor junior scientists and lead a team in assay development, data analysis, and experimental troubleshooting.
- Foster a culture of continuous learning, innovation, and scientific rigor within the team.

Minimum Requirements:

Education:
- PhD in immunology, neuroscience, cell biology, or related fields with a focus on GI, inflammatory diseases, or neurological disorders.
- Alternatively, MS with 13+ years of experience or BS with 15+ years of experience.
Experience:
- At least 6 years of experience in biologics research in Gastroenterology, Inflammation, or Neuroscience.
- Proven track record in leading in vitro pharmacology efforts, including assay development, screening, and mechanism of action studies.
Technical Expertise:
- Expertise in in vitro techniques such as cell-based assays, flow cytometry, and high-content imaging, particularly in inflammatory, GI, and neuronal models.
- Strong understanding of drug discovery processes, including lead identification, candidate selection, and preclinical development.
Leadership:
- Demonstrated leadership and mentoring experience in managing scientific teams and direct reports.
- Ability to lead cross-functional teams and influence project direction with scientific insights.
Communication Skills:
- Excellent communication and interpersonal skills for collaboration in a matrixed organization.
Regulatory Knowledge:
- Knowledge of regulatory requirements and guidelines for biologic drug discovery and development.

Compensation and Benefits:

Salary Range: $149,100 - $234,300 (based on experience and qualifications).
Benefits:
- Health insurance (medical, dental, vision).
- 401(k) with company match.
- Paid vacation, sick time, and holidays.
- Tuition reimbursement and wellness benefits.

Work Environment:

This position is onsite in Boston, MA, and is classified as full-time.

About Takeda:

Takeda is a global leader in R&D-driven pharmaceuticals, focusing on transformative biologics therapies in oncology, gastroenterology, and neuroscience. The company is committed to delivering innovative therapies for patients worldwide. Takeda offers a collaborative and inclusive workplace, fostering growth and career development.

This role provides an exciting opportunity to lead innovative research strategies in biologics and make a meaningful impact in the development of novel therapies for GI, inflammatory diseases, and neurological disorders.

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Scientific Associate Director, Gi, Inflammation, & Neuroscience, In Vitro Pharmacology

Job Description

Position Overview:

Key Responsibilities:

Minimum Requirements:

Compensation and Benefits:

Work Environment:

About Takeda:

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