Principal Clinical Scientist
Locations Available: Santa Clara (CA), Temecula (CA), St. Paul (MN), Westford (MA)
Category: Medical and Clinical Affairs
Work Model: Onsite (Daily Onsite Presence Required)
About Abbott
Abbott is a global healthcare leader dedicated to advancing health through innovative diagnostics, medical devices, nutrition solutions, and branded generic medicines. With more than 114,000 employees across 160+ countries, Abbott delivers technologies that support healthier lives at every stage.
Role Overview
The Principal Clinical Scientist is a senior-level scientific leadership role within Abbott’s Vascular Division. This position is responsible for designing, executing, and directing clinical studies supporting regulatory submissions and strategic business needs. The role requires strong scientific expertise, cross-functional leadership, and the ability to drive clinical evidence generation for vascular medical devices.
This is a full-time onsite position at one of the listed Abbott Vascular locations.
Key Responsibilities
Clinical Study Design & Strategy
Design clinical trials and studies in collaboration with cross-functional teams including clinical operations, biostatistics, data management, medical affairs, and regulatory affairs
Support clinical strategies aligned with premarket approval (PMA), 510(k) submissions, and broader business objectives
Provide scientific and technical guidance to internal and external stakeholders, including steering committees, investigators, and regulatory partners
Scientific Leadership
Serve as Clinical Science Lead on study teams, providing justification for trial design and ongoing scientific analysis
Support generation of pre-protocol documentation and pre-submissions to regulatory authorities
Lead or contribute to clinical protocols, case report forms, study reports, informed consent forms, and related documentation
Data Analysis & Communication
Critically evaluate clinical data and present findings to clinicians, leadership teams, and regulatory bodies
Lead podium strategy, abstract submissions, manuscripts, and publications in collaboration with investigators and internal teams
Synthesize scientific literature and competitive intelligence across therapeutic areas
Regulatory Support
Prepare scientific documents for regulatory submissions and respond to queries from global regulatory authorities
Lead and present at FDA or other regulatory meetings
Ensure adherence to quality system requirements and regulatory guidelines
Process Improvement & Mentorship
Identify opportunities to optimize clinical processes and internal workflows
Support innovation initiatives with new ideas and scientific perspectives
Mentor and guide junior clinical science team members
Required Qualifications
Bachelor’s degree required; advanced degree (MS, PhD, MD, PharmD) strongly preferred
Minimum 8+ years of relevant experience in clinical research, medical device development, or a scientific/technical discipline
Strong expertise in a relevant technological field, preferably cardiovascular or vascular devices
Proven ability to work on complex problems requiring advanced scientific judgment
Experience operating in a regulated environment (FDA, ISO standards, quality systems)
Demonstrated leadership in cross-functional scientific teams
Preferred Qualifications
Proficiency in MS Office Suite
Experience in the medical device industry
Clinical trial design and execution experience
Background in vascular or cardiovascular therapeutic areas
Compensation
Base Salary Range: 112,000 USD – 224,000 USD
Actual compensation may vary based on location and candidate seniority. Hiring typically aligns with the midpoint of the range.
Why Join Abbott
Comprehensive career development with a globally recognized healthcare leader
Free medical coverage eligibility for employees through Abbott’s HIP PPO plan
Competitive retirement savings plan with high employer contribution
Tuition assistance, student debt support programs, and FreeU bachelor’s degree pathway
Recognized as one of the world’s most admired and inclusive employers
Apply Now
Interested candidates can apply through Abbott’s official career portal.
Abbott is an Equal Opportunity Employer committed to building a diverse and inclusive workforce.
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