Postdoctoral Fellow – NMR/HDX-MS | Drug Discovery
Location: Emeryville, California, USA
Start Date: September 2025
Salary: $87,000 per year
Job Type: Full-time | Fellowship (up to 3 years, extendable)
Work Mode: On-site
Job Summary
Novartis is seeking a Discovery Postdoctoral Fellow with expertise in NMR spectroscopy and HDX-MS to drive drug discovery initiatives targeting cellular surface receptors. Based in Emeryville, California, this role is ideal for PhDs passionate about cutting-edge biophysics, molecular interaction studies, and interdisciplinary pharmaceutical research. This prestigious program fosters scientific innovation and provides training in radioligand therapies, siRNA, and antibody-drug conjugates.
Key Responsibilities
Design and implement biophysical experiments to study protein-ligand interactions on living cells
Establish workflows using on-cell NMR and HDX-MS to support drug discovery pipelines
Validate findings with orthogonal techniques and in-vitro models
Collaborate with interdisciplinary teams across discovery science and disease areas
Disseminate research through publications, presentations, and internal reports
Engage in Novartis Postdoctoral community programs, seminars, and collaborative learning
Explore fundamental scientific questions while advancing industry-relevant skillsets
Required Skills & Qualifications
PhD in Structural Biology, Biochemistry, Biophysics, or related field
Extensive experience in BioNMR (Ligand-Observed and Protein-Observed techniques)
Familiarity with HDX-MS and/or cell culture is highly desirable
Strong record of scientific publications or equivalent achievements
Passion for exploratory science, critical thinking, and method development
Excellent organizational, presentation, and communication skills
Must have received PhD on or after May 2023 or be in final year of thesis work
Perks & Benefits
Starting salary: $87,000/year
Comprehensive health, life, and disability insurance
401(k) plan with company contribution and matching
Generous time-off package: vacation, personal days, and holidays
Access to Novartis Life Handbook for rewards and benefits
Postdoc Practicum opportunities in labs or business functions
Professional development, global networking, and mentorship
Option to extend fellowship up to 4 years
Company Description
Novartis Institutes for BioMedical Research (NIBR) is the innovation engine of Novartis, driving transformative drug discovery. Located in Emeryville, CA, the Structural BioAnalytics team empowers novel therapeutics through advanced biophysical tools and interdisciplinary collaboration.
Work Mode
On-site – Emeryville, California, USA
Call to Action
Are you ready to reimagine medicine and shape the future of drug discovery? Apply now to become a Discovery Postdoctoral Fellow at Novartis.
Submit your CV and cover letter by August 1st, 2025 and accelerate your scientific journey in a world-class pharmaceutical research environment.
Apply now on ThePharmaDaily.com
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