Medical Lead – Oncology, Medical Affairs (MA-US)
Location: Northbrook, IL – Hybrid / Field-Based
Department: Medical Affairs – US
Job Type: Full-Time
Salary Range: $215,600 – $338,800 (based on experience and qualifications)
Company Overview
Astellas Pharma Inc. is a leading global pharmaceutical company operating in over 70 countries, dedicated to transforming innovative science into impactful medical solutions. Focused on unmet medical needs and guided by ethics and integrity, Astellas advances patient health worldwide. Learn more at www.astellas.com.
This role is based in Northbrook, Illinois. Remote work from eligible states may be considered under Astellas’ Responsible Flexibility Guidelines.
Position Summary
The Medical Lead – Oncology, MA-US is responsible for developing and executing medical and scientific strategies for assigned products within the Therapeutic Area (TA). This includes oversight of regional Medical Affairs activities, strategic planning, evidence generation, and scientific engagement with internal and external stakeholders.
This role requires collaboration across Medical, Clinical, Regulatory, HEOR, Commercial, and other cross-functional teams to ensure alignment with global medical strategies and support for business objectives in the US region.
Key Responsibilities
Strategic Leadership
Develop and implement robust medical and scientific plans for assigned oncology products
Oversee and execute MA-sponsored clinical studies, including HEOR research and investigator-sponsored studies
Lead medical advisory boards and provide input for clinical development and product lifecycle strategies
Guide cross-functional product teams in aligning medical strategy with business needs
Represent MA-US within the Medical Affairs Team (MAT) and ensure execution of global Core Medical Plan (CMP) tactics
Scientific Expertise & Communication
Provide medical and scientific expertise for promotional and non-promotional materials, including presentations, dossiers, and educational content
Collaborate with MSL teams to translate field insights into regional and global strategies
Review investigator-sponsored research proposals and chair committees as applicable
Support product labeling and periodic safety reporting in collaboration with Regulatory Affairs and Pharmacovigilance
Maintain up-to-date knowledge of disease states, therapeutic trends, and US healthcare environment
Stakeholder Engagement
Engage external experts, healthcare providers, and key stakeholders to gather insights and inform medical strategy
Serve as a trusted scientific advisor within the US region
Facilitate alignment and collaboration across multiple functions to achieve business and medical objectives
Required Qualifications
Education: MD, DO, or PharmD
Experience:
Minimum 2 years in Medical Affairs within the pharmaceutical industry
Proven experience collaborating in matrix organizations across Medical, Clinical, Regulatory, HEOR, Epidemiology, Medical Information, and Commercial teams
Strong analytical, strategic, and project management skills
Expertise in clinical trial design, evaluation, and medical evidence generation
Excellent communication and presentation skills (written and verbal, English)
Ability to lead cross-functional teams and engage internal and external stakeholders effectively
Approximately 20% travel required
Preferred Qualifications
Postgraduate specialization in Oncology or relevant therapeutic area
Experience with US healthcare systems, policy, and market access dynamics
Proven ability to support product launches and lifecycle management
Work Environment
Hybrid model combining office-based collaboration and flexible remote work
Field travel for congresses, advisory boards, and strategic meetings (~20%)
Compensation & Benefits
Competitive salary range: $215,600 – $338,800
Medical, dental, and vision insurance
Generous PTO including vacation, sick leave, and national holidays
401(k) match and annual company contribution
Company-paid life insurance
Annual corporate bonus and quarterly incentives (eligible positions)
Long-term incentive plan (eligible positions)
Company fleet vehicle (eligible positions)
Employee referral bonus program
Why Join Astellas?
Lead innovative oncology medical strategies and scientific programs
Collaborate with cross-functional teams and top healthcare experts
Contribute to the development of therapies that improve patient outcomes globally
Thrive in a flexible and inclusive work environment
Astellas is an equal opportunity employer, including Disability and Protected Veterans.
Apply Now
Qualified candidates will be reviewed by our recruitment team and contacted with next steps.
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