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Medical Director Pharmacovigilance

8+ years
Not Disclosed
10 Nov. 22, 2024
Job Description
Job Type: Full Time Education: B.Sc./ M.Sc./ M.Pharm/ B.Pharm/ Life Sciences Skills: Causality Assessment, Clinical SAS Programming, Communication Skills, CPC Certified, GCP guidelines, ICD-10 CM Codes, CPT-Codes, HCPCS Codes, ICD-10 CM, CPT, HCPCS Coding, ICH guidelines, ICSR Case Processing, Interpersonal Skill, Labelling Assessment, MedDRA Coding, Medical Billing, Medical Coding, Medical Terminology, Narrative Writing, Research & Development, Technical Skill, Triage of ICSRs, WHO DD Coding

Position Title: Medical Director - Pharmacovigilance

Location: Cambridge, MA
Job Type: Contract


Company Description

Katalyst Healthcares & Life Sciences specializes in contract research for clinical trials involving drugs, biologics, and medical devices. The company collaborates with university hospitals, pharmaceutical companies, and recruiting partners to provide expertise in Drug Safety, Pharmacovigilance, and Clinical Research.


Job Responsibilities

Developmental Program Support

  • Contribute to early and late-stage development programs as required.

  • Oversee signal detection and risk management activities for designated global/regional products.

  • Support Therapeutic Lead in safety-related initiatives.

Team Management

  • Provide line management for junior physicians and scientists.

  • Train and mentor Pharmacovigilance Physicians and Specialists.

Leadership Responsibilities

  • Serve as the Global Safety Lead (GSL) for compounds in development and marketed products.

  • Act as a companywide safety expert for assigned compounds.

  • Lead strategic safety programs and initiatives.

Regulatory Documentation and Negotiation

  • Develop and review regulatory documents such as safety summaries, MAAs, NDAs, and Integrated Analyses of Safety (IAS).

  • Negotiate safety-related matters with regulatory authorities.

  • Author executive summaries and risk/benefit profiles for compounds.

Global Pharmacovigilance Physician Activities

  • Review and oversee clinical and non-clinical safety data.

  • Provide input and sign-off on study protocols, statistical analysis plans (SAPs), clinical study reports, IBs, and regulatory submission documents.

  • Interact with external experts, regulatory agencies, and co-development partners.

  • Lead safety data analysis and prepare risk management plans and safety monitoring plans.

  • Direct safety procedures and develop safety exchange agreements for co-development projects.


Required Qualifications

Education

  • Qualified physician (License preferred, e.g., GMC registered).

  • Knowledge of epidemiology and statistics.

Experience

  • Minimum of 8 years in pharmacovigilance, clinical research, or clinical development.

  • 2-3 years of clinical experience post-graduate training with substantial knowledge of general medicine.

Skills

  • Strong critical thinking, analytical, and decision-making skills.

  • Proficiency in Microsoft applications and statistical analysis tools.

  • Excellent written and verbal communication skills, including presenting to large internal and external groups.

  • Exceptional organizational and project management capabilities.


Additional Skills

  • Professional interpersonal skills to collaborate with senior executives, contractors, and colleagues.

  • Thorough analytical and numerical skills for multi-tasking and prioritizing.

  • Experience in leading cross-functional teams and regulatory negotiations.


Key Competencies

  • Strategic and proactive leadership in safety programs.

  • Expertise in safety signal detection and risk management.

  • Ability to train, mentor, and lead diverse teams effectively.