Global Head of Project Delivery Operations
Updated: Yesterday
Location: London, England, United Kingdom
Job ID: 25105074-OTHLOC-3526-2DR
Employment Type: Full-Time | Global Leadership Role
About Syneos Health
Syneos Health® is a leading, fully integrated biopharmaceutical solutions organization dedicated to accelerating customer success. By combining clinical development, medical affairs, and commercial expertise, Syneos Health delivers end-to-end solutions that help bring life-changing therapies to patients faster.
With a workforce of more than 29,000 professionals across 110+ countries, Syneos Health operates at the forefront of global clinical research and development, driven by its mission of Shortening the Distance from Lab to Life®.
Role Overview
The Global Head of Project Delivery Operations is a senior, enterprise-critical leadership role within Global Project Delivery. This position is responsible for defining the global operating framework and driving operational excellence across Project Management, Clinical Supply Trial Management, Central Services (bidding, budgeting, proposal data management), and Trial Master File (TMF) operations.
Reporting to the Head of Global Project Delivery, this role provides strategic direction, governance, and performance oversight across a complex global portfolio, ensuring consistent, high-quality delivery while enabling scalable and sustainable business growth.
Key Responsibilities
Global Project Delivery & Project Management Leadership
Provide strategic and operational leadership for the global Project Management function across regions and therapeutic areas
Establish and maintain global standards, governance frameworks, and best practices for project planning, execution, risk management, and reporting
Ensure effective oversight of study timelines, milestones, deliverables, and portfolio-level performance
Foster a culture of accountability, proactive risk management, and continuous improvement
Clinical Supply Trial Management Oversight
Lead and govern Clinical Supply Trial Management to ensure alignment with study requirements, timelines, and regulatory expectations
Partner with Clinical Operations, Supply Chain, and external vendors to ensure reliable, compliant, and timely delivery of clinical trial supplies
Integrate clinical supply planning into program- and study-level project plans
Central Services Leadership (Bidding, Budgeting & Proposals)
Oversee global Central Services supporting bid development, budgeting, and proposal data management
Ensure accuracy, consistency, and competitiveness of study budgets, pricing assumptions, and proposal inputs
Drive standardization of pricing tools, historical cost intelligence, and proposal data to support scalable business development
Collaborate closely with Sales, Finance, Proposals, and Operations teams to deliver high-quality, timely bid responses
Trial Master File (TMF) Strategy & Governance
Provide global oversight of TMF strategy, governance, and operational performance
Ensure TMF completeness, inspection readiness, quality, and compliance with global regulatory requirements
Lead continuous improvement initiatives across TMF processes, systems, metrics, and inspection preparedness
Financial & Operational Stewardship
Partner with Finance and executive leadership to ensure strong financial performance, forecasting accuracy, margin delivery, and cost control
Ensure project-level financial discipline, including budget adherence, change control, and revenue recognition support
Monitor portfolio-level KPIs and implement corrective actions as required
Stakeholder, Client & Executive Engagement
Act as a senior escalation point for complex delivery, operational, and client issues
Build strong, collaborative relationships across Clinical Operations, Quality, Regulatory, IT, Finance, and Commercial teams
Support client satisfaction, retention, and long-term growth through effective operational partnership
Talent, Capability & Organizational Development
Lead, develop, and inspire a global, multi-layered leadership organization
Drive talent strategy, succession planning, leadership development, and workforce scalability
Promote a culture of high performance, engagement, and accountability
Required Experience & Qualifications
15+ years of progressive experience in project delivery or project management leadership within a CRO, biopharmaceutical, or clinical research environment
Proven experience overseeing large, global, multi-study clinical portfolios
Demonstrated leadership across Project Management, Clinical Supply Trial Management, TMF operations, and proposal/bid support
Strong financial acumen with experience in budgeting, forecasting, portfolio management, and margin delivery
Proven ability to lead and influence senior leaders in a highly matrixed, global organization
Track record of driving operational transformation, standardization, and scalable growth
Bachelor’s degree required; advanced degree in Life Sciences, Business, or a related field preferred
Key Skills & Competencies
Enterprise-level leadership and operational integration
Strategic thinking combined with hands-on execution capability
Deep understanding of global clinical research operations and CRO delivery models
Excellent communication skills, executive presence, and stakeholder management
Strong change leadership and continuous improvement mindset
Compensation & Benefits
Salary Range: USD 204,600 – 378,600 (or local equivalent based on location)
Compensation will be determined based on experience, qualifications, and role alignment.
Syneos Health offers a competitive total rewards package, which may include executive-level benefits, performance-based incentives, flexible paid time off, health and wellness programs, and long-term growth opportunities.
Why Join Syneos Health
Over the past five years, Syneos Health has supported:
94% of all Novel FDA-approved drugs
95% of EMA-authorized products
200+ studies across 73,000 sites and more than 675,000 clinical trial patients
At Syneos Health, leaders are empowered to challenge the status quo, drive innovation, and deliver meaningful impact across the global clinical research landscape.
Additional Information
This job description is not exhaustive and may evolve based on business needs. Equivalent experience and qualifications may be considered. This posting does not constitute an employment contract. Syneos Health is an equal opportunity employer and complies with all applicable employment and accessibility regulations.
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