Clinical Research Coordinator II (Hybrid) – Dallas & Euless, Texas | Syneos Health
Updated: November 14, 2025
Location: Dallas & Euless, Texas, USA
Job ID: 25103668
Employment Type: Hybrid (On-site + Remote)
About the Role
Syneos Health, in partnership with Illingworth Research Group, is seeking a Clinical Research Coordinator II (CRC II) to support and coordinate assigned clinical trials across multiple therapeutic areas. This hybrid role is based in Dallas and Euless, TX and involves planning, execution, monitoring, and close-out of clinical research studies in accordance with GCP, ICH guidelines, SOPs, and regulatory requirements.
Illingworth Research Group operates in over 45 countries, specializing in patient-centric clinical services including mobile research nursing, patient concierge, medical photography, and clinical research operations.
Key Responsibilities
Clinical Trial Planning & Start-Up
Review study protocols, ICFs, Investigator Brochures, and related documentation for accuracy and feasibility.
Prepare and maintain the Investigator Site File (ISF) and Trial Master File (TMF).
Participate in study start-up activities, timelines, investigator meetings, and sponsor discussions.
Coordinate clinic logistics, training, schedules, and study materials.
Collaborate with cross-functional teams on safety assessments, QC plans, monitoring procedures, pharmacy requirements, and study supplies.
Ensure all regulatory and contractual documents are complete before study initiation.
Support the Principal Investigator in delegation logs, task management, visit calendars, and monitor coordination.
Lead participant recruitment, advertising, and screening.
Clinical Conduct
Conduct study activities in compliance with GCP and regulatory standards.
Manage multiple clinical trials simultaneously.
Protect patient safety and confidentiality.
Collect and enter study data; ensure on-time submission of CRFs and other documentation.
Assist with informed consent procedures.
Coordinate screening, eligibility checks, dosing, randomization, and follow-up visits.
Supervise clinic visits and provide on-call support when necessary.
Review adverse events, serious adverse events, study logs, updates, and monitoring findings.
Maintain strong communication with participants and study teams to minimize protocol deviations.
Post-Clinic & Close-Out
Resolve QC issues, monitoring findings, and documentation queries.
Oversee study close-out processes including TMF updates, deviation reports, CRF sign-offs, and archiving.
Manage return of study supplies and IRB close-out requirements.
Prepare for sponsor, monitor, and QA audits.
Provide timely updates to Project Managers and sponsors.
Participate in process improvement, SOP revisions, and internal initiatives.
Work flexible hours including evenings and weekends when required.
Regulatory Compliance
Maintain protocol amendments, consents, and renewal submissions.
Report adverse events to appropriate authorities.
Maintain complete and accurate study files.
Travel up to 100% as needed.
Qualifications & Experience Required
Education
Registered Nurse (RN) and/or Bachelor’s degree in Science required.
Clinical Research Certification preferred.
Professional Experience
Minimum 1 year of clinical research experience required; 2+ years preferred.
Experience coordinating clinical research projects is strongly preferred.
Strong knowledge of ICH-GCP, regulatory guidelines, and privacy regulations.
Skills & Competencies
Excellent planning, problem-solving, and time-management capabilities.
Strong attention to detail and ability to handle multiple deadlines.
Effective communication and teamwork skills.
Knowledge of SOP development and documentation standards.
Ability to anticipate issues and deliver timely solutions.
Proficiency in MS Office tools (Word, Excel, PowerPoint).
Experience with EDC systems preferred.
Compensation & Benefits
Salary Range: USD 67,700 – 115,100
Actual salary is based on skills, experience, and qualifications.
Benefits may include:
Company car or car allowance
Comprehensive medical, dental, and vision coverage
401(k) with company match
Employee Stock Purchase Plan
Performance-based bonus/commission eligibility
Flexible paid time off (PTO) and paid sick time (state-specific compliance)
About Syneos Health
Syneos Health is committed to creating an inclusive and diverse workplace. Candidates whose experience does not perfectly align with every requirement are encouraged to apply. Transferable skills are valued, and professional growth is supported through training, mentorship, and internal career pathways.
Job Summary
The Clinical Research Coordinator II will coordinate and support clinical research studies while ensuring compliance with protocols, SOPs, and regulatory frameworks. This role requires a strong ability to manage complex workflows and collaborate across multidisciplinary teams.
Apply Now
If you are ready to advance your career in clinical research, submit your application today.
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