Clinical Operations Therapeutic Area Leader – Cardiovascular, Renal & Metabolism (Cvrm)

10-15 years

$227,600 – $422,600,

Remote

10 Nov. 20, 2025

Job Description

Job Type: Full Time Education: B.Sc./ M.Sc./ M.Pharm/ B.Pharm/ Life Sciences Skills: Causality Assessment, Clinical SAS Programming, Communication Skills, CPC Certified, GCP guidelines, ICD-10 CM Codes, CPT-Codes, HCPCS Codes, ICD-10 CM, CPT, HCPCS Coding, ICH guidelines, ICSR Case Processing, Interpersonal Skill, Labelling Assessment, MedDRA Coding, Medical Billing, Medical Coding, Medical Terminology, Narrative Writing, Research & Development, Technical Skill, Triage of ICSRs, WHO DD Coding

Clinical Operations Therapeutic Area Leader – Cardiovascular, Renal & Metabolism (CVRM)
Locations: Available in 4 Global Locations | Category: Research & Development | Job ID: 202504-108216

About the Role
Roche/Genentech Pharma Product Development Global Clinical Operations (PDG) is committed to transforming drug development and delivering 20 transformative medicines by 2029. As part of this mission, we are seeking a Clinical Operations Therapeutic Area Leader – Cardiovascular, Renal & Metabolism (CVRM). This senior leadership role carries strategic and operational oversight for the clinical development portfolio across CVRM, with significant influence across the global Roche enterprise.

This position is designed for an experienced leader ready to drive global clinical operations strategy, portfolio execution, stakeholder alignment, and innovative delivery models across high-impact therapeutic areas.

Key Responsibilities

Strategic Portfolio Leadership

Define, evolve, and oversee the global clinical operations strategy for the CVRM portfolio.
Ensure alignment with the Clinical Development Plan (CDP) and Roche’s One Pharma Strategy.
Prioritize portfolio activities based on scientific, operational, and strategic considerations.

Operational Oversight and Risk Management

Maintain continuous visibility across studies and assets to monitor progress, risks, and dependencies.
Implement effective mitigation strategies to ensure seamless global trial execution.

Cross-Functional and Enterprise Collaboration

Drive collaboration across PDG, APO, COEs, early/late-stage development teams, and additional enterprise partners.
Provide strategic operational leadership to influence decision-making and optimize development timelines and outcomes.

Innovation in Clinical Operations

Leverage analytics and data-driven insights to improve quality, efficiency, and probability of technical success (PTS).
Champion patient-centric approaches and promote innovative methodologies across the clinical operations framework.

Enterprise Representation and External Engagement

Serve as the senior PDG representative for CVRM, partnering with internal leadership, regulatory agencies, vendors, and patient advocacy groups to support strategic goals.

People Leadership and Team Development

Lead a matrixed global team of approximately 150 employees, including 10–12 direct reports.
Build a high-performing, inclusive culture emphasizing collaboration, accountability, and scientific excellence.

Organizational Leadership

Represent CVRM within the Portfolio Delivery Leadership Team, contributing to broader PDG and PD initiatives.
Oversee administrative responsibilities, performance management, and development planning for team members.

Who You Are – Experience & Qualifications

Required Experience

15+ years of pharmaceutical clinical operations experience, with at least 10 years in global clinical operations strategy leadership.
Deep expertise in Cardiovascular, Renal, and Metabolism therapeutic areas, including global development trends, regulatory expectations, and operational challenges.
Comprehensive understanding of international clinical development, including large-scale endpoint-driven trials.
Proven track record in:
- Strategic planning and execution
- Data-driven decision-making
- Improving access and trial inclusivity
- Achieving ambitious portfolio goals
Experience leading and developing large matrixed organizations with multiple layers of direct and indirect reporting.
Strong stakeholder management capabilities and ability to influence senior leaders across complex global environments.
Fluency in English; additional language skills are an asset.
Ability to travel frequently nationally and internationally.

Preferred Characteristics

Experience collaborating with regulatory authorities and global health agencies.
Demonstrated success driving organizational transformation and operational innovation.

Location & Compensation

This position may be based in one of the following Roche sites:

Basel, Switzerland
South San Francisco, United States
Welwyn Garden City, England
Mississauga, Canada

On-site presence is required in alignment with local policies. Relocation benefits are available.

California Salary Range:
$227,600 – $422,600, depending on experience, location, and qualifications.
A discretionary annual bonus may be available based on individual and company performance.
Comprehensive Roche benefits apply.

About Roche
With more than 100,000 employees worldwide, Roche is dedicated to advancing science, accelerating medical innovation, and ensuring global access to healthcare. Our medicines reach over 26 million people, and our diagnostics solutions support more than 30 billion tests annually. We foster a culture that encourages creativity, collaboration, and ambition to drive meaningful impact.

Apply Now
Join Roche in shaping the future of clinical development across high-impact therapeutic areas and advancing groundbreaking medicines for patients worldwide.

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Clinical Operations Therapeutic Area Leader – Cardiovascular, Renal & Metabolism (Cvrm)

Job Description

Who You Are – Experience & Qualifications

Location & Compensation

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