Translational Science / Biomarker Operations Expert
Sponsor-Dedicated | Spain or United Kingdom
Updated: February 3, 2026
Location: United Kingdom (London) or Spain
Job ID: 25105448-OTHLOC-3526-2DR
Employment Type: Full-Time | Sponsor-Dedicated
Function: Translational Science | Biomarker Operations | Clinical Development
About Syneos Health
Syneos Health® is a leading fully integrated biopharmaceutical solutions organization committed to accelerating customer success. By combining expertise across clinical development, medical affairs, and commercial operations, Syneos Health transforms scientific insight into meaningful outcomes that address modern healthcare challenges.
With approximately 29,000 professionals across more than 110 countries, Syneos Health is united by a shared mission of Shortening the Distance from Lab to Life® through collaboration, innovation, and scientific excellence.
Role Overview
The Translational Science / Biomarker Operations Expert is a sponsor-dedicated role responsible for the operational execution of biomarker and translational science activities across clinical trials. This position serves as a key interface between Translational Science, Clinical Operations, Data Management, Biostatistics, laboratory vendors, and external partners to ensure high-quality biomarker sample collection, data integrity, and timely delivery of translational insights.
This role is critical in enabling precision medicine strategies and supporting regulatory-compliant biomarker operations across global clinical development programs.
Key Responsibilities
Translational Science & Biomarker Operations
Collaborate closely with Translational Science Leads, Clinical Operations, Biostatistics/Bioinformatics, and Data Management teams to support and execute translational science strategies within clinical trials.
Provide operational input into study protocols, lab manuals, sample management plans, and other study documentation to ensure biomarker activities align with GCP, ICH, and regulatory requirements.
Act as the primary point of contact for biomarker operations across internal functions, CROs, laboratories, and external collaborators.
Data & Vendor Management
Partner with Data Management teams to support biomarker-related database setup, data formats, transfer specifications, reconciliation, and delivery timelines.
Manage global laboratory vendors, including contracting support, oversight of timelines, data quality control, reporting, and issue resolution.
Support mutual data transfers with Companion Diagnostics (CDx) partners for regulatory submissions when required.
Sample Logistics & Oversight
Oversee clinical biomarker sample logistics, including site feasibility assessments, site training, sample shipment, and real-time sample tracking.
Ensure continuous sample reconciliation and provide oversight to support selection of samples for downstream analysis.
Monitor operational performance and proactively address risks related to sample integrity, timelines, and data completeness.
Analysis & Continuous Improvement
Support biomarker data analysis activities, including data processing, curation, integration, and development of tables, figures, and listings.
Share operational learnings across studies and programs, identifying best practices and opportunities for process improvement.
Contribute to a culture of collaboration, accountability, and continuous improvement across translational science initiatives.
Required Qualifications & Experience
Education
Bachelor’s degree in Life Sciences, Biomedical Sciences, Molecular Biology, or a related discipline.
Advanced degree (Master’s or PhD) is preferred.
Experience
Minimum 5–8 years of relevant industry experience in translational science, biomarker operations, or clinical drug development.
Hands-on experience with clinical laboratory sample processing and/or biomarker analysis in a clinical research environment.
Proven experience supporting precision medicine strategies and biomarker-driven clinical trials.
Skills & Competencies
Strong understanding of clinical drug development processes and biomarker integration across study phases.
Demonstrated experience managing global laboratory vendors and external partners.
Solid project management, planning, and organizational skills with the ability to manage multiple priorities independently.
Strong critical thinking, problem-solving, and attention to detail.
Proven ability to lead and collaborate within cross-functional, multicultural, and geographically dispersed teams.
Excellent verbal and written communication skills in a global professional environment.
Adaptive mindset with the ability to work in iterative cycles and support inclusive, high-performing teams.
Talent Pipeline Notice
This posting represents a potential upcoming opportunity rather than an active opening. Candidates expressing interest will be added to the Syneos Health talent pipeline and considered for future openings aligned to this role.
Why Join Syneos Health
Contribute to biomarker-driven precision medicine programs with global impact.
Work in a sponsor-dedicated model with deep scientific collaboration.
Access ongoing professional development, technical training, and career progression opportunities.
Be part of a diverse, inclusive organization committed to scientific excellence and innovation.
Compliance & Equal Opportunity Statement
This job description is not intended to be exhaustive. Syneos Health reserves the right to modify responsibilities as business needs evolve. Equivalent combinations of education, skills, and experience may be considered.
Syneos Health is an equal opportunity employer and complies with all applicable employment legislation, including the EU Equality Directive and the Americans with Disabilities Act (ADA). Reasonable accommodations will be provided where required.
SEO & AI Search Keywords
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