Principal Scientist

Roche

6+ years

$117,700 - $218,500

Remote, USA Washington

10 Feb. 13, 2025

Job Description

Job Type: Remote Education: B.Sc./ M.Sc./ M.Pharm/ B.Pharm/ Life Sciences Skills: Causality Assessment, Clinical SAS Programming, Communication Skills, CPC Certified, GCP guidelines, ICD-10 CM Codes, CPT-Codes, HCPCS Codes, ICD-10 CM, CPT, HCPCS Coding, ICH guidelines, ICSR Case Processing, Interpersonal Skill, Labelling Assessment, MedDRA Coding, Medical Billing, Medical Coding, Medical Terminology, Narrative Writing, Research & Development, Technical Skill, Triage of ICSRs, WHO DD Coding

Job Title: Principal Scientist

Location: Seattle, Washington, United States of America
Category: Research & Development
Job ID: 202410-125730

Position Overview

At Roche, we advance science to create a healthier future for everyone. We are committed to advancing DNA sequencing technology through the acquisition of Stratos Genomics in 2020, which brought Sequencing by Expansion (SBX™) technology to the forefront. This unique chemistry revolutionizes nanopore sequencing by translating DNA sequences into measurable surrogates, significantly enhancing accuracy and throughput.

As a Principal Scientist, you will play a key role in the Molecular Engineering group, working on developing and synthesizing the building blocks for this groundbreaking technology. Your work will directly contribute to advancing DNA sequencing and improving patient outcomes. We're looking for someone with a deep technical background, leadership skills, and a passion for making SBX technology a success.

Key Responsibilities:

Research and Experimentation:
- Design and execute well-controlled experiments with high attention to detail.
- Lead innovative research and troubleshoot complex problems creatively.
- Contribute to the definition and achievement of project goals.
Leadership and Mentorship:
- Lead cross-functional teams, mentoring junior team members and ensuring they are equipped to perform at their best.
SOP Development and Reagent Production:
- Develop Standard Operating Procedures (SOPs) to streamline the production of reagents and starting materials.
- Participate in the production of reagents, ensuring quality and consistency.
Data Analysis & Protocol Development:
- Conduct thorough data analysis and support the development of lab protocols.
- Maintain accurate and reliable laboratory records.
Collaboration & Presentation:
- Present findings and progress at group or departmental meetings.
Lab Maintenance:
- Maintain the lab’s cleanliness, organization, and safety.
Process Improvement:
- Continuously propose and implement process improvements to enhance lab functions and outcomes.

Who You Are

Educational Qualifications:
- Bachelor’s Degree in Organic Synthesis, Chemistry, Chemical Engineering, Biochemistry, or a related field with 10+ years of experience.
- Master’s Degree in a related field with 9+ years of experience.
- PhD in a related field with 6+ years of experience.
Technical Expertise:
- 6+ years of laboratory experience in advanced nucleotide/heterocyclic chemistry, phosphorus chemistry, or complex/multi-step organic synthesis.
- Strong understanding and experience with the chemistry of nucleotides, phosphoramidites, heterocycles, amino acids, and bio-conjugations.
- Solid background in next-generation DNA sequencing (NGS).
- Experience working with HPLC, MS, NMR, automated DNA synthesizers, inert atmosphere chambers, and manual pipetting.
Preferred Experience:
- Familiarity with SBX technology, nanopore sequencing, and other emerging technologies in DNA sequencing.
Skills & Competencies:
- Strong leadership, mentorship, and team collaboration skills.
- Ability to work independently and thrive in a fast-paced, dynamic environment.
- Excellent problem-solving and troubleshooting abilities.
- Deep understanding of chemical and biochemical sample handling, reactivity, purification, and storage.

Why Roche?

Roche is at the forefront of advancing healthcare through science and technology. As a Principal Scientist, you will be working on pioneering SBX technology, contributing to the development of next-generation sequencing methods that can transform patient outcomes. This is a rare opportunity to make a significant impact on healthcare while working in a collaborative and innovative environment.

Additional Information:

Salary Range: $117,700 - $218,500 (based on experience, qualifications, geographic location, and other job-related factors).
Discretionary Annual Bonus: Available based on individual and company performance.
Relocation Benefits: Available for this position.

Note: Please include a cover letter outlining why you want to work with Roche, your specific technical interest in SBX technology, and how you would contribute to the team. This is an important part of the application process.

How to Apply

If you're ready to lead innovative research, contribute to the development of revolutionary technology, and be part of a world-class team, apply today for the Principal Scientist position at Roche. Join us in advancing DNA sequencing for a healthier tomorrow!

Recommended Jobs

Senior Research Director, Patient Experience – Coa Strategy Location: Wilmington, North Carolina, Usa (Fully Remote) Job Id: R-01325877 Job Type: Full-Time Category: Clinical Research Senior Research

Thermo Fisher Scientific

Remote

Pharma Jobs in India

Gujarat :

Maharashtra :

Haryana :

Andra Pradesh :

Tamil Nadu :

Himachal Pradesh :

Baddi | Solan |

Rajasthan :

Karnataka :

Punjab :

Madhya Pradesh :

Odisha :

Bhubaneswar | Rourkela |

Chhattisgarh :

Bilaspur | Eot Municipality | Raipur |

Uttarakhand :

Delhi :

Delhi | India | New Delhi | PAN-India |

Assam :

Dibrugarh | Diburghar | Guwahati |

West Bengal :

Digha | Kolkata | Mukundapur |

Uttar Pradesh :

Goa :

Goa | Panaji | Verna |

Bihar :

Hajipur | Patna |

Kerala :

Pondicherry (Puducherry) :

Pondicherry (Puducherry) |

Jharkhand :

Ranchi |

Sikkim :

Rangpo |

India :

Siliguri |

Pharma Jobs in United States

Illinois :

Maryland :

Texas :

California :

New York :

New Mexico :

Albuquerque | Farmington | Santa Fe | Tucumcari |

Pennsylvania :

Alaska :

Massachusetts :

Wisconsin :

United states :

Georgia :

Atlanta | Augusta | Rome |

Maine :

Bangor | Brewer |

New Jersey :

Ohio :

LA :

Baton Rouge | Monroe | New Orleans |

Washington :

Oregon :

Wyoming :

Big Piney | Cokeville |

Alabama :

Birmingham |

Virginia :

Blacksburg | Charlottesville | Falls Church | Mechanicsville |

Indiana :

Bloomington | West Lafayette |

Florida :

Idaho :

Boise |

Colorado :

Boulder | Denver | Westminster |

Connecticut :

North Caroline :

Arizona :

South Carolina :

Charleston |

Kansas :

North Carolina :

Concord | Lumberton | North Carolina |

Michigan :

Detroit | Houghton Lake | Macomb | Southfield |

North Dakota :

Dickinson |

Minnesota :

Kentucky :

Edgewood | Ft MItchell | Louisville | Shelbyville |

Arkansas :

Fort Smith |

Kington :

Frank Scottile Blvd |

Missouri :

Fulton | Milan | St. Louis |

United States :

Hawai | kentucky | Sylmar | Woonsocket |

Nebraska :

Hebron | Nebraska City |

Hawaii :

Hilo | Honolulu |

Tennessee :

Knoxville | Memphis | Nashville |

Louisiana :

Lake Charles | Shreveport |

Nevada :

Las Vegas | Tonopah | Tonopsh | Virginia |

New Hampshire :

Lebanon | Macon | Manchester |

Portugal :

Lisbon | Oeiras | Portugal |

WI :

Madison | Wausau |

Republic of Mexico :

Mexico |

northeastern :

New Hampshire |

Oklahoma :

Oklahoma City |

Puerto Rico :

San Juan |

Albama :

Tuscaloosa |

D.C :

Washington |

Delaware :

Wilmington |

Pharma Jobs in Germany

North Rhine Westphalia :

Munich :

Bavaria |

Bavaria :

Brandenburg :

Berlin |

Baden-Wurttemberg :

Hesse :

Darmstadt | Marburg |

Hessen :

Frankfurt | Harveysburg |

Germany :

Germany | GErmany |

Lower Saxony :

Gottingen | Hannover | Leipzig |

Saxony Anhalt :

Halle |

Rotherbaum :

Hamburg |

Rhineland Palatinate :

Ingelheim am Rhein | Mainz |

Schleswig Holstein :

Kiel |

Berlin :

Mitte |

Mecklenburg Vorpommern :

Rostock |

Saarland :

Saarbrucken |

Pharma Jobs in Europe

Switzerland :

Basel | Zurich |

Serbia :

Belgrade | Serbia |

Hungary :

Budapest |

BULGARIA :

Bulgaria | Vedant |

Denmark :

Copenhagen | Denmark |

Europe :

Finland :

Finland |

Istanbul :

Istanbul | Turkey |

Norway :

Norway | NOrway |

Romania :

Romania |

Belgium :

Wavre |

Pharma Jobs in Ireland

Tipperary :

Ballydine |

Cork :

Brinny | Ringaskiddy |

Carlow :

Carlow |

Republic of Ireland :

Cork | Dublin | Limerick | Waterford |

Ulster :

Donegal |

Meath :

Dunboyne |

Dún Laoghaire :

Dún Laoghaire |

Galway :

Galway |

County Dublin :

Swords |

Pharma Jobs in China

Republic of China :

Beijing |

China :

China | Quarry Bay |

Liaoning :

Dalian |

Zhejiang :

Hangzhou |

Tokiyo :

Osaka | Tokyo |

Shanghai Sai :

Shanghai Shi |

Hubei :

Wuhan |

Pharma Jobs in Netherland

Capital of Netherland :

Amsterdam |

North Brabant :

Breda |

Noord Holland :

Haarlem |

South Holland :

Leiden |

Netherlands :

Netherlands |

Pharma Jobs in Australia

Remote Australia :

Arkansas | Remote Australia |

New South Wales :

Ballina | Sydney |

Republic of Western Australia :

Nedlands |

Queensland :

Queensland |

Melbourne :

South Yarra |

Pharma Jobs in United Kingdom

Surrey :

Chessington | Pirbright |

Antrim :

Larne |

Cheshire :

Runcorn |

Hertfordshire :

Welwyn |

Pharma Jobs in England

United Kingdom :

North Yorkshire :

Harrogate |

South Yorkshire :

Sheffield |

Oxfordshire :

Witney |

Pharma Jobs in Canada & Belgium & South America & Greece & New Zealand & Austria & Spain & Philippines & Croatia & Estonia & Vietnam & Italy & Indonesia & Japan & Finland & Korea & Kazakhstan & Thailand & Israel & Remote & Colombia & Tennessee & Romania & Argentina & Egypt & Mexico & United Arab Emirates & Saudi Arabia & malaysia & Ukraine & Peru & France & South Afrcia & Serbia & Czechia & Chile & Bosnia and Herzegovina & Singapore & Bulgaria & Sweden & Taiwan & Poland

Ontario :

Canada :

Canada |

Quebec :

Montreal |

Brussels :

Brussels |

Antwerp :

Heist op den Berg |

Flemish Brabant :

Zaventem |

South America :

Peru | Argentina |

Brazil :

Sao paulo | Brazil |

Attica :

Athens | Koropi |

Greece :

Greece |

North Island :

Auckland |

New Zealand :

New Zealand |

Austria :

Austria |

Vienna :

Vienna |

Catalonia :

Barcelona |

Madrid :

Madrid |

Cebu Province :

Cebu City |

Philippines :

Manila |

Croatia :

Croatia |

Zagreb :

Zagreb |

Estonia :

Tartu | Estonia |

Harju County (Maakond) :

Tallinn |

Hà Nội :

Hà Nội | Hanoi |

Ho Chi Minh :

Ho Chi Minh City |

Italy :

Italy |

Lombardy :

Rho |

Jakarta :

Jakarta |

East Java :

Surabaya |

Japan :

Saitama | Japan |

Tokyo :

Otemachi |

North Ostrobothnia :

Oulu |

Southwest Finland (Varsinais-Suomi) :

Turku |

Remote Korea :

Remote Korea |

Republic of Korea :

Seoul |

Kazakhstan :

Almaty |

Republic of Thailand :

Bangkok |

Israel :

Remote :

Republic of Colombia :

Bogota |

Williamson :

Brentwood |

Bucharest :

Bucharest |

Buenos Aires :

Buenos Aires |

Republic of Egypt :

Cairo |

Mexico :

Ciudad de México | New Mexico |

Dubai :

Dubai |

Makkah :

Kuala Lumpur :

Kuala Lumpur |

Kyiv Oblast :

Kyiv |

Lima Region :

Lima |

France :

Lyon | Paris |

South Africa :

South Africa | Midrand |

Nišava District :

Niš |

Bohemia :

Prague |

Chile :

Santiago |

Bosnia and Herzegovina :

Sarajevo |

Singapore :

Singapore |

Sofia City :

Sofia |

Sweden :

Sweden |

Taipei :

Taipei |

Mazovia :

Warsaw |

Welcome Back

Create Account