Senior Director – Gene Therapy Medical Affairs
Location: Indianapolis, Indiana, USA
Category: Medical Affairs
Job Type: Full-Time, Regular
Job ID: R-95063
About the Company
Lilly is a global healthcare leader committed to uniting scientific discovery with compassionate care. Headquartered in Indianapolis, the company focuses on developing life-changing medicines, advancing disease understanding, and improving global health. With a strong culture of innovation, Lilly empowers its teams to deliver meaningful impact for patients worldwide.
Position Overview
The Senior Director – Gene Therapy Medical Affairs will lead medical strategy across Lilly’s expanding gene therapy portfolio, including sensory disorders, rare diseases, and neurodegenerative conditions. This leader will serve as a key scientific interface with global experts, treatment centers of excellence, patient advocacy networks, and internal cross-functional teams.
The role requires deep expertise in gene therapy, strategic insight generation, cross-functional collaboration, and the ability to drive medical excellence across global markets.
Key Responsibilities
1. Scientific & Strategic Leadership
Act as the scientific authority for gene therapy across multiple therapeutic areas.
Stay updated on emerging science, competitive intelligence, and evolving treatment paradigms.
Lead development of medical strategies, launch plans, and evidence-generation roadmaps.
Collaborate with clinical development, commercial teams, regulatory affairs, ethics and compliance, and other internal partners.
2. Expert & Stakeholder Engagement
Build and maintain strong relationships with KOLs, clinicians, scientific societies, and patient organization leaders.
Identify knowledge gaps, unmet needs, diagnostic barriers, and emerging opportunities in global markets.
Deliver scientific education and support scientific exchange initiatives.
3. Gene Therapy Centers of Excellence
Provide training, scientific support, and operational guidance to treatment centers.
Support the removal of site-specific challenges related to gene therapy administration.
Strengthen partnerships to optimize patient access and clinical implementation.
4. Insights & Evidence Generation Support
Gather field insights to inform medical strategy, advocacy initiatives, clinical programs, and commercial planning.
Communicate consolidated insights across internal teams to guide decision-making.
5. Education & Scientific Communication
Oversee development and review of scientific content for internal teams, healthcare professionals, and patient communities.
Support educational initiatives on genetic testing, diagnostic pathways, and gene therapy mechanisms.
Provide scientific training to internal stakeholders.
6. Clinical Trial Support
Support trial awareness activities and provide feedback on patient and clinician perspectives.
Collaborate with clinical development to enhance trial feasibility and engagement.
7. Compliance & Governance
Ensure all activities adhere to internal policies, federal regulations, and industry guidelines.
Demonstrate sound judgment related to scientific interactions and dissemination.
Basic Qualifications
PharmD or PhD in a scientific/medical discipline with 8+ years of relevant industry experience;
OR a Master’s degree with 10+ years of experience in relevant therapeutic areas.
Experience in Medical Affairs or Patient Advocacy.
Background in genetics, gene therapy, or rare diseases.
Preferred Qualifications
Strong learning agility with the ability to interpret and communicate complex scientific concepts.
Excellent verbal and written communication skills.
Demonstrated ability to manage multiple priorities independently.
Advanced scientific presentation skills and expertise in literature evaluation.
Strong interpersonal skills and experience building professional networks.
Experience supporting customers with complex scientific inquiries.
Field-based medical experience is highly valued.
Willingness to travel approximately 40%, including international travel.
Compensation & Benefits
Anticipated Salary Range: USD $154,500 – $226,600
Actual compensation will vary based on experience, education, skills, and geographic location.
Eligible employees may also receive:
Annual company bonus
401(k) and pension benefits
Medical, dental, vision, and prescription coverage
Life insurance and disability benefits
Flexible spending accounts
Paid vacation and leave programs
Employee well-being and assistance programs
Fitness and wellness benefits
Participation in employee clubs and ERGs
Inclusion Commitment
Lilly is an Equal Opportunity Employer and does not discriminate on any legally protected status. The organization offers strong employee resource groups supporting cultural, medical, veteran, disability, and LGBTQ+ communities.
Applicants requiring accommodations for the application process may submit requests through the company’s official accommodation form.
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