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Senior Clinical Team Manager (Prin.) - Hemonc

0-2 years
Not Disclosed
10 Nov. 13, 2025
Job Description
Job Type: Full Time Education: B.Sc/M.Sc/M.Pharma/B.Pharma/Life Sciences Skills: Causality Assessment, Clinical SAS Programming, Communication Skills, CPC Certified, GCP guidelines, ICD-10 CM Codes, CPT-Codes, HCPCS Codes, ICD-10 CM, CPT, HCPCS Coding, ICH guidelines, ICSR Case Processing, Interpersonal Skill, Labelling Assessment, MedDRA Coding, Medical Billing, Medical Coding, Medical Terminology, Narrative Writing, Research & Development, Technical Skill, Triage of ICSRs, WHO DD Coding

osition Title:

Senior / Principal Clinical Team Manager (HemOnc)

Location: Remote – North Carolina, USA
Company: Thermo Fisher Scientific Inc. (PPD® Clinical Research Division)
Job ID: R-01327955
Job Type: Full-time
Category: Clinical Research
Work Schedule: Standard (Mon–Fri)
Work Environment: Office / Fully Remote


About the Role

Join the world’s leading global CRO under Thermo Fisher Scientific, where our Clinical Research Services team drives innovation in developing life-changing therapies. As a Senior/Principal Clinical Team Manager (CTM), you will lead regional or global teams in hematology and oncology (HemOnc) trials, ensuring that our clinical research achieves the highest standards in quality, efficiency, and compliance.

This is an opportunity to manage impactful, high-complexity projects in therapeutic areas including:

  • Ovarian Cancer

  • Sickle Cell

  • Non-Hodgkin’s Lymphoma

  • Multiple Myeloma

  • Glioma

  • Head & Neck

  • Pancreas

  • Prostate

  • Non-Small Cell Lung

  • Breast

  • Colorectal

  • Radiopharmaceuticals

  • Cell & Gene Therapy / CAR-T


Key Purpose

Responsible for achieving final clinical deliverables—clean, evaluable data within agreed timelines and budgets—while ensuring compliance with ICH-GCP and client expectations. The CTM leads clinical teams, manages operational delivery, and maintains profitability through effective project and team management.


Essential Responsibilities

1. Clinical Operations Leadership

  • Lead all operational and quality aspects of moderate to high-complexity clinical studies.

  • Develop and implement clinical monitoring tools (e.g., Monitoring Plan, Guidelines).

  • Oversee setup, organization, and maintenance of Trial Master File (TMF).

  • Ensure timely regulatory submissions and ethics committee responses.

2. Project Management & Delivery

  • Partner with the Project Manager to oversee timelines, deliverables, and budgets.

  • Conduct regular team meetings to ensure alignment, resource management, and performance tracking.

  • Monitor project metrics, CRF collection, query resolution, and clinical data quality.

  • Implement corrective actions when deliverables are at risk.

3. Cross-functional Collaboration

  • Work closely with Project Management, Data Management, and Regulatory teams to ensure integrated delivery.

  • Contribute to protocol design, CRF and consent form development.

  • Represent the clinical team in client meetings, bid defenses, and project hand-offs.

4. People Management

  • Mentor, train, and motivate clinical team members to achieve project and personal growth objectives.

  • Conduct accompanied field visits (AFVs) and performance evaluations.

  • Allocate resources effectively and forecast clinical activity requirements.

5. Compliance and Quality Oversight

  • Ensure adherence to global and regional regulatory guidelines (ICH-GCP, FDA, EMA).

  • Implement standardized monitoring processes and ensure timely archiving of study materials.

  • Maintain high ethical standards aligned with company and sponsor policies.


Qualifications & Experience

Education

  • Bachelor’s degree in Life Sciences, Medicine, Pharmacy, or a related field (required).

  • Advanced degree (Master’s / Ph.D.) preferred.

Experience

  • Minimum 8+ years of experience in clinical research.

  • Proven leadership in managing global or regional clinical teams in Hematology/Oncology studies.

  • Strong experience in managing trials across multiple therapeutic areas listed above.


Knowledge, Skills & Abilities

  • Excellent leadership and mentoring skills; ability to motivate and integrate teams.

  • Strong project management, organizational, and prioritization abilities.

  • Deep understanding of clinical monitoring practices and GCP regulations.

  • Sound financial acumen: budgeting, forecasting, and fiscal management.

  • Effective decision-making, risk management, and escalation handling.

  • Strong written and verbal communication (English proficiency required).

  • Proficient in MS Office (Word, Excel, Outlook) and clinical systems.


Working Environment

  • Work in a remote/office environment with standard working hours.

  • May involve travel up to 20% (automobile, air, or train).

  • Ability to work under pressure and manage multiple priorities.

  • May occasionally encounter healthcare or lab-based environments.


Our Values – The 4i Culture

  • Integrity

  • Innovation

  • Intensity

  • Involvement

If you’re passionate about accelerating the delivery of safe and effective therapeutics and share our 4i values, we invite you to apply and become part of our mission to make the world healthier, cleaner, and safer.