Job Title:
Scientific Director – Peptide Process Chemistry – SMDD
Location:
Indianapolis, Indiana, United States
Job ID: R-86259
Category: Research & Development
Job Type: Full-Time, Regular
Company Overview:
Eli Lilly and Company is a global healthcare leader headquartered in Indianapolis, Indiana. We unite caring with discovery to bring life-changing medicines to patients worldwide and support communities through philanthropy and volunteerism.
Position Summary:
Join the Synthetic Molecule Design and Development (SMDD) division as a Scientific Director specializing in peptide process chemistry. Lead sustainable peptide development and commercialization projects in a collaborative, multi-disciplinary environment spanning the U.S., Asia, and Europe. Drive innovative, green chemistry approaches to peptide manufacturing at commercial scale.
Key Responsibilities:
Lead a team of peptide chemists in designing and optimizing sustainable synthetic peptide processes.
Oversee multi-kilogram peptide process development at contract manufacturing organizations (CMOs).
Educate CMOs on greener peptide synthesis best practices.
Collaborate with Lilly Development and Manufacturing teams to advance peptide manufacturing initiatives.
Present findings internally and externally; publish in peer-reviewed journals.
Utilize and promote Tag Assisted Liquid Phase Peptide Chemistry and hybrid SPPS/LPPS methodologies.
Basic Qualifications:
PhD in Chemistry or related field
7+ years in pharmaceutical industry OR 12+ years in related industries or academia
Expertise in peptide synthesis including hybrid SPPS/LPPS
Proven leadership and team management skills
Preferred Skills:
Strong collaborative interpersonal skills
Flexibility and ability to prioritize competing demands
Track record of scientific innovation and publication
Familiarity with chromatography, mass spectrometry, optical spectroscopy, and peptide automation
Travel:
0 to 10%
Compensation:
Salary Range: $144,000 – $250,800
Bonus eligibility based on performance
Comprehensive benefits package including 401(k), pension, health, and wellness programs
Inclusion & Accessibility:
Lilly supports diversity and equal opportunity employment. For accommodation requests during the application process, please use this form:
👉 Workplace Accommodation Request
Employee Resource Groups:
Lilly offers ERGs including PRIDE, WILL, OLA, enAble, Veterans Leadership Network, and more to foster community and support.
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