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Scientific Director - Peptide Process Chemistry – Smdd

7-12 years
$151,500 – $222,200
10 June 4, 2025
Job Description
Job Type: Remote Education: PhD Skills: Causality Assessment, Clinical SAS Programming, Communication Skills, CPC Certified, GCP guidelines, ICD-10 CM Codes, CPT-Codes, HCPCS Codes, ICD-10 CM, CPT, HCPCS Coding, ICH guidelines, ICSR Case Processing, Interpersonal Skill, Labelling Assessment, MedDRA Coding, Medical Billing, Medical Coding, Medical Terminology, Narrative Writing, Research & Development, Technical Skill, Triage of ICSRs, WHO DD Coding

 

Job Title:

Scientific Director – Peptide Process Chemistry – SMDD

Location:

Indianapolis, Indiana, United States
Job ID: R-86259
Category: Research & Development
Job Type: Full-Time, Regular


Company Overview:

Eli Lilly and Company is a global healthcare leader headquartered in Indianapolis, Indiana. We unite caring with discovery to bring life-changing medicines to patients worldwide and support communities through philanthropy and volunteerism.


Position Summary:

Join the Synthetic Molecule Design and Development (SMDD) division as a Scientific Director specializing in peptide process chemistry. Lead sustainable peptide development and commercialization projects in a collaborative, multi-disciplinary environment spanning the U.S., Asia, and Europe. Drive innovative, green chemistry approaches to peptide manufacturing at commercial scale.


Key Responsibilities:

  • Lead a team of peptide chemists in designing and optimizing sustainable synthetic peptide processes.

  • Oversee multi-kilogram peptide process development at contract manufacturing organizations (CMOs).

  • Educate CMOs on greener peptide synthesis best practices.

  • Collaborate with Lilly Development and Manufacturing teams to advance peptide manufacturing initiatives.

  • Present findings internally and externally; publish in peer-reviewed journals.

  • Utilize and promote Tag Assisted Liquid Phase Peptide Chemistry and hybrid SPPS/LPPS methodologies.


Basic Qualifications:

  • PhD in Chemistry or related field

  • 7+ years in pharmaceutical industry OR 12+ years in related industries or academia

  • Expertise in peptide synthesis including hybrid SPPS/LPPS

  • Proven leadership and team management skills


Preferred Skills:

  • Strong collaborative interpersonal skills

  • Flexibility and ability to prioritize competing demands

  • Track record of scientific innovation and publication

  • Familiarity with chromatography, mass spectrometry, optical spectroscopy, and peptide automation


Travel:

0 to 10%


Compensation:

  • Salary Range: $144,000 – $250,800

  • Bonus eligibility based on performance

  • Comprehensive benefits package including 401(k), pension, health, and wellness programs


Inclusion & Accessibility:

Lilly supports diversity and equal opportunity employment. For accommodation requests during the application process, please use this form:
👉
Workplace Accommodation Request


Employee Resource Groups:

Lilly offers ERGs including PRIDE, WILL, OLA, enAble, Veterans Leadership Network, and more to foster community and support.