Job Title: R&D Scientist
Job ID: 290285
Location: Madison, Wisconsin, United States
Job Type: Full-time
Company: MilliporeSigma (Mirus Bio)
About the Company
For over 25 years, Mirus Bio, part of MilliporeSigma, has pioneered the manufacture of transfection reagents and proprietary technologies for nucleic acid delivery applications. With a focus on research and GMP-grade products, the company supports researchers in the cell and gene therapy space.
Mission: Empower Discovery. Enable Innovation. Improve Life.
Position Summary
The R&D Scientist will join the R&D Chemistry Team to develop the next generation of transfection reagents, enhancers, and related products. This role involves hands-on polymer synthesis work and reports directly to the Director of Chemistry.
Key Responsibilities
Independently design, execute, and analyze laboratory experiments for new/existing transfection technologies and products.
Contribute new product ideas and assess their technical feasibility.
Perform organic and polymer chemistry reactions (including under inert conditions using Schlenk line and reflux).
Synthesize and characterize novel compounds; prepare samples and conduct routine analytical testing.
Apply analytical techniques: TLC, GPC, HPLC, NMR, FTIR, UV, DLS, MS, pH meter.
Utilize purification and separation methods: extraction, distillation, precipitation, recrystallization, chromatography.
Maintain a detailed laboratory notebook and track synthesized materials in compliance with Good Documentation Practices.
Collaborate with Production, Quality, and Operations teams to ensure alignment.
Present findings in R&D meetings and participate in knowledge-sharing sessions.
Perform additional duties as assigned by the Director of Chemistry.
Qualifications
Minimum Requirements
Ph.D. in Polymer Chemistry.
Experience synthesizing and characterizing polymers for biomedical applications (e.g., nucleic acid or drug delivery).
Preferred Requirements
2+ years designing, synthesizing, and characterizing polymers for nucleic acid delivery.
Industrial R&D experience under GxP guidelines and regulations.
Strong organizational skills with ability to manage multiple priorities.
Ability to work independently and in multi-disciplinary teams.
Proficiency in Microsoft Office (Excel, Word, PowerPoint).
Travel Requirements
Up to 5% travel, including overnight.
Location Requirements
Onsite role at Madison, WI facility.
Compensation & Benefits
Salary Range: $76,600 – $107,200 (based on skills, experience, and location).
Benefits may include:
Medical, vision, and dental insurance
Life and disability insurance
401(k) matching program
Paid time off and holidays
Short- and long-term incentive compensation (e.g., cash bonuses)
Work Culture & Values
Inclusive environment with diverse perspectives driving innovation.
Opportunities for professional development and growth.
Culture of creativity, initiative, responsibility, and respect.
Commitment to equity, inclusion, and belonging.
Equal Employment Opportunity (EEO)
The Company is an Equal Opportunity Employer. Applicants and employees are considered without discrimination based on race, color, religion, age, sex, sexual orientation, national origin, ancestry, disability, veteran status, genetic information, gender identity, marital status, or any other protected classification.
Reports of discrimination can be made to HR, Legal, or Compliance. Retaliation for good-faith reports is prohibited.
Additional Notices
Work Authorization: This role does not offer sponsorship. Applicants must be legally eligible to work in the U.S.
North America Disclosure: Residents of certain states (CA, CO, HI, MD, NY, WA, DC) can request additional compensation/benefits details.
Massachusetts Disclosure: Employers may not require or administer lie detector tests as a condition of employment.
Fraudulent Job Offers: Beware of unauthorized third parties offering fake job opportunities.
What We Offer
Beyond financial rewards, MilliporeSigma provides a wide range of benefits and opportunities to help employees work their magic, spark discovery, and elevate humanity.
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