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Qa Senior Manager

8-14 years
Not Disclosed
10 Feb. 17, 2025
Job Description
Job Type: Full Time Education: B.Sc./ M.Sc./ M.Pharm/ B.Pharm/ Life Sciences Skills: Causality Assessment, Clinical SAS Programming, Communication Skills, CPC Certified, GCP guidelines, ICD-10 CM Codes, CPT-Codes, HCPCS Codes, ICD-10 CM, CPT, HCPCS Coding, ICH guidelines, ICSR Case Processing, Interpersonal Skill, Labelling Assessment, MedDRA Coding, Medical Billing, Medical Coding, Medical Terminology, Narrative Writing, Research & Development, Technical Skill, Triage of ICSRs, WHO DD Coding

Job Title: QA Senior Manager

Location: India - Hyderabad
Work Location Type: On-Site
Date Posted: Feb. 04, 2025
Category: Quality


Job Summary:

Join Amgen’s mission to change the world! As a QA Senior Manager, you will play a critical role in ensuring all Quality Requirements are met, managing GMP inspections, and supporting inspection readiness activities. You’ll oversee Design History Files (DHF), contribute to design and development strategies, and collaborate cross-functionally to drive excellence in Combination Product Operations.


Key Responsibilities:

  • Provide Quality technical expertise, oversight, and serve as a single point of contact for Combination Product Operations activities.

  • Attend development program meetings as part of program working teams.

  • Guide documentation structures, ensuring GMP or Non-GMP phase-appropriate strategies and repositories for compliance.

  • Act as QA contact for change controls and review relevant Design Control documentation.

  • Create and maintain Design History File Index, Device Design Traceability Matrix, Quality Combination Product Plan, and EDO Control Plan.

  • Provide Quality oversight of Design Characterization, Verification, and Validation activities.

  • Contribute to regulatory submissions and respond to RTQs; support audits and inspections.

  • Ensure program alignment within Design and Development Plans, Risk Management Documentation, and EDO Control Plans.

  • Provide oversight for Human Factors Engineering (HFE) protocols and reports.

  • Participate in deviation, CAPA, and complaint investigations for commercial programs.

  • Support internal/external audits and inspections with preparedness and formal responses.

  • Act as an independent reviewer for combination product program design reviews.

  • Collaborate with CPO for management review topics and provide quality advice on regulatory strategies.

  • Manage program budgets and evidence-based resource planning.

  • Lead and develop highly qualified staff, ensuring operational excellence.


Basic Qualifications:

  • Doctorate degree and 2 years of quality and/or design space experience OR

  • Master’s degree and 8 to 10 years of quality and/or design space experience OR

  • Bachelor’s degree and 10 to 14 years of quality and/or design space experience OR

  • Diploma and 14 to 18 years of quality and/or design space experience


Preferred Qualifications:

  • Quality and manufacturing experience in biotech or pharmaceutical industries.

  • Expertise in NPI/NPD (New Product Introduction/Development).

  • Strong leadership skills with the ability to manage multiple complex projects.

  • Familiarity with GMP, GDP, and pharmaceutical regulations.

  • Experience in audit cycles and interfacing with regulators.

  • Knowledge of quality engineering, mechanical engineering, and applicable standards (e.g., MDR, ISO 14971, ICH Q9/Q8/Q10, ISO 13485, EU Annex 1, 21 CFR parts 4, 820, 210, 211).

  • Prior experience with combination product launch teams.

  • Effective negotiation, workload management, and decision-making skills.

  • Ability to travel up to 20% domestically and internationally.