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Oncology Early Stage Clinical Scientist Senior Manager

2-6 years years
$135,100 - $225,100
10 Sept. 4, 2025
Job Description
Job Type: Full Time Education: PhD/PharmD with 2+ years clinical scientist experience, OR MA/MBA/MS with 5+ years clinical development including 2 years clinical scientist role with proven oncology development success, OR BA/BS/B Skills: Causality Assessment, Clinical SAS Programming, Communication Skills, CPC Certified, GCP guidelines, ICD-10 CM Codes, CPT-Codes, HCPCS Codes, ICD-10 CM, CPT, HCPCS Coding, ICH guidelines, ICSR Case Processing, Interpersonal Skill, Labelling Assessment, MedDRA Coding, Medical Billing, Medical Coding, Medical Terminology, Narrative Writing, Research & Development, Technical Skill, Triage of ICSRs, WHO DD Coding

Oncology Early Stage Clinical Scientist Senior Manager (Two Positions)

Locations:

  • La Jolla, California, USA

  • Bothell, Washington, USA

  • Groton, Connecticut, USA

  • Collegeville, Pennsylvania, USA

  • New York City, New York, USA

Employment Type:

  • Full-time

Posted:

  • 23 Days Ago

Job ID:

  • 4939685


Our Purpose

We’re in relentless pursuit of breakthroughs that change patients’ lives. We innovate every day to make the world a healthier place.

Our Values

To fully realize Pfizer’s purpose — Breakthroughs that change patients’ lives — we have clear expectations about what to achieve for patients and how to achieve those goals.

Pfizer Research & Development

Pfizer R&D is the heart of Pfizer's innovative product pipeline, focused on bringing life-changing medicines to the world.

Benefits

Pfizer offers competitive compensation and benefits designed to meet the diverse needs of our colleagues.


Position Summary

Collaborate with the Global Development Lead (GDL) and the development team to establish, lead, coordinate, and execute early oncology clinical development plans for novel biological or small molecule therapies. Support studies from first-in-human (FIH), proof of mechanism (POM), early signals of efficacy (ESOE), to proof of concept (POC). May receive mentoring from senior clinicians. Depending on experience, may lead clinical protocol development and contribute as an individual contributor on study teams.


Key Responsibilities

  • Support GDL in executing clinical development strategy for assigned molecules/indications.

  • Lead or support preparation of clinical protocols and critical documents (protocol amendments, investigator brochures, regulatory documents).

  • Collaborate with Clinical Operations to ensure timely, high-quality execution of FIH programs through proof-of-concept with innovative designs.

  • Participate in safety assessments and interpretation of clinical study results.

  • Regularly review individual and cumulative safety data with Safety Risk Lead and GDL.

  • Support transitioning early development programs to late-stage development when appropriate.

  • Prepare presentations on strategy and data; assist in authoring clinical sections of regulatory documents (Investigator Brochures, Annual Reports, IND sections, Clinical Study Reports).

  • Support development of publications, abstracts, and presentations.

  • Interface with safety sciences, statistics, PK/PD, regulatory, outcomes research, development operations, governance, external experts, and regulators fostering transparency and trust.

  • Support collaboration with project leaders and team members.

  • Partner with Translational Oncology and Biomarkers to ensure biomarker strategies support efficacy, proof of concept, and patient stratification.

  • Help build relationships with external experts, consultants, key opinion leaders, regulators, and investigator networks to integrate latest clinical guidelines and support study management.

  • May mentor others and review their work without formal managerial title.

  • Perform other clinical program duties as assigned.


Minimum Qualifications / Skills

  • PhD/PharmD with 2+ years clinical scientist experience, OR

  • MA/MBA/MS with 5+ years clinical development including 2 years clinical scientist role with proven oncology development success, OR

  • BA/BS/BSN with 7+ years clinical development including 2 years clinical scientist role with proven oncology development success.

  • Experience in early oncology drug development.

  • Familiarity with Biostatistics, Regulatory, Pre-Clinical Pharmacology, Pharmaceutical Sciences.

  • Strong scientific writing and communication skills.

  • Experience with GCP, Pfizer policies, and SOPs.

  • Proven ability to build consensus and drive change across all organizational levels.

  • Experience reviewing clinical data listings.

  • Ability to work collaboratively in fast-paced matrix teams and independently.

  • Experience with complex data analysis tools (JReview, SpotFire, SOCs-PRO, or similar).


Preferred Qualifications

  • Experience applying Pfizer policies and SOPs.

  • Demonstrated leadership in influencing, collaborating, coaching, overseeing, and guiding colleagues toward impactful outcomes.


Physical / Mental Requirements

  • Ability to perform complex data analysis.


Work Schedule and Travel

  • 5-10% Travel.

  • Hybrid work location.


Compensation & Benefits

  • Annual base salary range: $135,100 - $225,100.

  • Eligible for Pfizer’s Global Performance Plan with 17.5% bonus target.

  • Eligible for share-based long-term incentives.

  • Comprehensive benefits including 401(k) with matching, retirement contributions, paid vacation, holidays, personal days, caregiver/parental leave, and health coverage.


Additional Information

  • Relocation assistance may be available.

  • Compliance with Sunshine Act reporting requirements.

  • Equal Opportunity Employer.

  • Requires permanent U.S. work authorization.

  • Accessibility accommodations available via disabilityrecruitment@pfizer.com.


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