Hiring: Oncology Early Stage Clinical Scientist (Director, Non-MD)
📍 Locations:
United States: California (La Jolla, South San Francisco), Massachusetts (Cambridge), Washington (Bothell), Connecticut (Groton), New York (New York City)
💼 Job Type: Full-time
🆔 Job ID: 4939684
📅 Posted: 3 Days Ago
🌐 Work Arrangement: Hybrid
✈️ Travel: 5–10%
About Pfizer
Pfizer is on a mission to create breakthroughs that improve patient lives. Pfizer Research & Development drives innovation across therapeutic areas, including Oncology, delivering novel therapies safely and efficiently.
Position Summary
The Oncology Early Stage Clinical Scientist (Director, Non-MD) leads and coordinates early-stage clinical development studies, including:
First-in-Human (FIH)
Proof-of-Mechanism (POM)
Early Signs of Efficacy (ESOE)
Proof-of-Concept (POC) studies
This role partners closely with the Global Development Lead (GDL) to execute the clinical development plan and ensures scientific, operational, and regulatory excellence across assigned oncology programs.
Key Responsibilities
Clinical Leadership & Study Execution
Lead scientific execution of clinical studies and innovative trial designs.
Ensure high-quality trial execution, safety assessment, and interpretation of clinical results.
Oversee FIH to proof-of-concept programs, ensuring operational feasibility and data integrity.
Data Review & Analysis
Set clinical data review strategy, monitor quality data, and review emerging trends.
Analyze trial data in collaboration with GDL, Clinical Safety, and Biostatistics.
Present and discuss relevant data with internal and external stakeholders.
Protocol & Documentation
Lead preparation of clinical protocols, development plans, INDs, annual reports, CSRs, Investigator Brochures, and statistical analysis plans.
Contribute to scientific publications, abstracts, and presentations.
Collaboration & Cross-Functional Partnerships
Partner with internal teams: Research Units, Biostatistics, Clinical Pharmacology, Precision Medicine, Digital Medicine, Translational Oncology, and Development Operations.
Coordinate with external experts, consultants, KOLs, regulators, and investigator networks.
Integrate biomarker strategies and patient stratification into early efficacy studies.
Leadership & Team Development
Foster transparent partnerships and trust across teams.
Support functional area priorities and departmental initiatives.
Build consensus and drive change across organizational levels, including senior management.
Minimum Qualifications / Key Skills
Education & Experience:
PhD or PharmD + 5 years relevant experience, OR
MS + 7 years relevant experience, OR
BA/BS + 10 years relevant experience in industry/CRO.
Clinical research experience in Phase 1 Oncology studies on the sponsor side.
Strong knowledge of clinical procedures, ICH guidelines, GCP, FDA/EMA/global regulations.
Expertise in scientific writing and clinical document preparation (protocol, ICD, IB, IND).
Experience with clinical data review, analysis, and complex data interpretation.
Ability to work collaboratively in a matrixed team environment and independently when needed.
Track record of scientific productivity (publications, abstracts, presentations).
Preferred Qualifications
Experience leading a team.
Demonstrated ability to influence, collaborate, coach, and guide colleagues to achieve meaningful outcomes.
Competencies
Critical thinking and problem-solving in complex clinical scenarios.
Strong communication skills, both written and verbal.
Leadership in driving clinical development strategy and execution.
Ability to adapt in a fast-paced, dynamic environment.
Compensation & Benefits
Salary Range: $169,700 – $282,900
Bonus: Pfizer Global Performance Plan (20% target)
Benefits: 401(k) with matching contributions, retirement savings, paid vacation/holidays, medical, dental, vision, parental leave, and more.
Relocation: Assistance may be available based on business needs and eligibility.
Equal Opportunity & Eligibility
Pfizer is an equal opportunity employer. Permanent U.S. work authorization is required. Pfizer complies with all laws regarding nondiscrimination, work authorization, and accessibility.
🔗 Apply Now: Pfizer Careers – Oncology Early Stage Clinical Scientist
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