Job Title: Medical Director, Clinical Science – Solid Tumor
Location: Boston, Massachusetts, USA
Department: Clinical Science / Global Development Organization (GDO)
Job Level: Senior
Employment Type: Full-Time, Exempt
Travel: Minimal (15–25%)
Salary Range: $228,200 – $358,600 annually
Role Overview:
Takeda is seeking a Medical Director, Clinical Science – Solid Tumor to lead global clinical development programs for innovative oncology therapies. This senior role will oversee clinical strategy, study design, and execution across multiple regions (US, EU, Japan) while integrating medical, scientific, regulatory, and commercial perspectives. The position requires strong leadership of multi-disciplinary teams and direct collaboration with internal and external stakeholders, including regulatory authorities and key opinion leaders.
Key Responsibilities:
Lead global clinical development teams, providing strategic guidance for assigned solid tumor compounds.
Develop and execute comprehensive clinical development plans, including protocols, synopses, and regulatory submissions.
Oversee study execution, data interpretation, and integration into overall compound strategy.
Monitor patient safety and clinical trial conduct in collaboration with pharmacovigilance and clinical teams.
Make high-impact “go/no-go” and development plan decisions that influence regulatory approvals and commercial viability.
Serve as medical and scientific liaison for regulatory authorities, key opinion leaders, and alliance partners.
Participate in due diligence, business development, and alliance projects related to clinical development strategies.
Mentor, manage, and develop team members, promoting a culture of excellence, collaboration, and innovation.
Contribute to process improvements and adoption of AI/digital solutions for clinical trial innovation.
Qualifications & Experience:
MD, MD/PhD, or internationally recognized equivalent with ≥5 years of clinical research experience in oncology or biomedical/clinical research.
Strong expertise in solid tumor malignancies and late-phase clinical development.
Experience leading multi-regional, matrix clinical development teams.
Familiarity with immune-based therapies, antibody-drug conjugates, and NDA/MAA submission processes is preferred.
Knowledge of GCP, ICH guidelines, and global regulatory requirements.
Exceptional communication, leadership, and decision-making skills, with the ability to influence stakeholders at all levels.
Proven track record in strategic clinical planning and operational execution.
Why Join Takeda:
Takeda is committed to creating better health for people worldwide through innovative therapies. Certified as a Global Top Employer, Takeda provides a collaborative, inclusive, and values-driven workplace with opportunities for professional growth, competitive compensation, and comprehensive benefits, including medical, dental, vision, retirement plans, paid time off, and well-being programs.
Equal Opportunity Statement:
Takeda is an Equal Opportunity Employer, committed to diversity, equity, and inclusion. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, veteran status, or other legally protected characteristics.
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