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Study Start-Up Project Manager

5+ years
Not Disclosed
10 Nov. 21, 2025
Job Description
Job Type: Full Time Education: B.Sc/M.Sc/M.Pharma/B.Pharma/Life Sciences Skills: Causality Assessment, Clinical SAS Programming, Communication Skills, CPC Certified, GCP guidelines, ICD-10 CM Codes, CPT-Codes, HCPCS Codes, ICD-10 CM, CPT, HCPCS Coding, ICH guidelines, ICSR Case Processing, Interpersonal Skill, Labelling Assessment, MedDRA Coding, Medical Billing, Medical Coding, Medical Terminology, Narrative Writing, Research & Development, Technical Skill, Triage of ICSRs, WHO DD Coding

Global Study Start-Up Project Manager

Location: Remote – United States
Job Category: Site Activation & Maintenance
Job ID: 10828


Job Summary

Medpace, a leading full-service Clinical Research Organization (CRO), is seeking an experienced Global Study Start-Up Project Manager to join our rapidly growing Clinical Operations team. This role is critical in accelerating clinical trial initiation and ensuring regulatory and operational compliance across global study sites.

This position offers remote work flexibility with performance-based incentives, including competitive bonuses, sign-on/relocation bonuses, and equity awards for eligible candidates.


Key Responsibilities

  • Lead global study start-up, maintenance, and close-out activities to ensure timely execution and regulatory compliance

  • Serve as the primary Sponsor contact for start-up and regulatory submission activities

  • Perform quality checks on submission documents and site essential documentation

  • Prepare, review, and approve Informed Consent Forms and other study documentation

  • Conduct regulatory reviews to develop proactive solutions for study start-up challenges

  • Prepare new business proposals and contribute to bid defenses, general capabilities meetings, and audits

  • Provide mentorship and development to departmental staff, supporting process improvements and system enhancements

  • Collaborate across matrix teams to ensure project deliverables align with study timelines and quality standards


Required Experience & Qualifications

  • Bachelor’s degree in Life Sciences or a related field; Advanced degree preferred

  • 5+ years of clinical research experience, ideally in a senior or lead Study Start-Up role within a CRO

  • Demonstrated project management skills and ability to develop and mentor team members

  • Strong oral and written communication skills

  • Minimal travel required


Why Medpace?

Medpace is a globally recognized mid-sized CRO delivering Phase I–IV clinical development services across biotechnology, pharmaceutical, and medical device industries. Our disciplined and scientific approach accelerates the global development of safe and effective therapeutics, leveraging local regulatory and therapeutic expertise across multiple therapeutic areas, including oncology, cardiology, metabolic disease, endocrinology, CNS, anti-viral, and anti-infective.

  • Headquartered in Cincinnati, Ohio, with over 5,000 employees in 40+ countries

  • Strong focus on employee career growth, training, and development


Perks & Benefits

  • Flexible, remote-friendly work environment

  • Competitive PTO packages, starting at 20+ days

  • Comprehensive compensation and benefits package

  • Company-sponsored employee appreciation events

  • Employee health and wellness programs

  • Structured career growth and professional development paths

  • Local discounts for shopping, fitness, and entertainment


Awards & Recognition

  • Named a Top Workplace in 2024 by The Cincinnati Enquirer

  • Recognized by Forbes as one of America’s Most Successful Midsize Companies (2021–2024)

  • Recipient of CRO Leadership Awards from Life Science Leader magazine for expertise, quality, and reliability


Next Steps

Qualified candidates will be reviewed by the Medpace recruitment team. Shortlisted applicants will be contacted with next steps for the selection process.