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Global Development Lead, Medical Director, Oncology Early Development

2+ years
$219,800 – $366,400 annually
10 Sept. 4, 2025
Job Description
Job Type: Hybrid Education: MD or MD‑PhD Skills: Causality Assessment, Clinical SAS Programming, Communication Skills, CPC Certified, GCP guidelines, ICD-10 CM Codes, CPT-Codes, HCPCS Codes, ICD-10 CM, CPT, HCPCS Coding, ICH guidelines, ICSR Case Processing, Interpersonal Skill, Labelling Assessment, MedDRA Coding, Medical Billing, Medical Coding, Medical Terminology, Narrative Writing, Research & Development, Technical Skill, Triage of ICSRs, WHO DD Coding

Position Overview

Title: Global Development Lead, Medical Director, Oncology Early Development
Locations (USA):

  • California – La Jolla

  • California – South San Francisco

  • Washington – Bothell

  • Pennsylvania – Collegeville

  • New York – New York City

  • Massachusetts – Cambridge

  • Connecticut – Groton
    Employment Type: Full-time
    Work Model: Hybrid
    Posting Age: Posted more than 30 days ago
    Job ID: 4939075
    Pfizer


Role Summary

  • Lead and support early clinical development of oncology assets—from first-in-human through proof-of-concept.

  • Shape clinical development plans, including combination strategies and predictive/pharmacodynamics biomarker considerations.

  • Provide clinical expertise to project teams, including medical monitoring of trials.

  • Oversee transition of assets from early R&D to late-stage (typically phase III) oncology clinical development.
    PfizerTeal


Key Responsibilities

  • Strategize and execute development for early-stage oncology assets across multiple indications.

  • Manage at least two clinical programs and support additional research projects.

  • Collaborate across multifunctional teams (e.g., Product, Clinical Pharmacology, Regulatory Strategy).

  • Oversee preparation and review of:

    • Clinical protocols and amendments

    • Investigator brochures

    • Clinical study reports

    • Statistical analysis plans

    • Regulatory documents

  • Lead early-stage clinical scientists in a matrixed environment with colleagues from various disciplines.

  • Implement innovative trial designs, including PK-guided dose escalation and early combination strategies.

  • Evaluate safety, pharmacology, and efficacy data from both ongoing and completed studies.

  • Manage scientific communications—manuscripts, abstracts, presentations—for conferences and advisory boards.

  • Conduct literature reviews and support development programs with summaries.

  • Serve as a medical resource for clinical/preclinical program interpretation.

  • Coordinate interactions (quarterly or as needed) with clinical trial networks and KOL advisory boards for feedback integration.

  • Drive early clinical development innovation, with emphasis on translational oncology and precision medicine.

  • Translate preclinical discoveries into therapeutic candidates through cross-functional collaboration.

  • Partner with business development to forge external collaborations and new research initiatives.
    PfizerTeal


Basic Qualifications

  • MD or MD‑PhD, with ≥2 years of industry experience in oncology drug development (especially early-phase).

  • Board certification in oncology preferred.

  • Demonstrated leadership in clinical, translational, or biomedical research areas.

  • Strong understanding of biostatistics, regulatory affairs, preclinical pharmacology, and pharmaceutical sciences.

  • Proven scientific productivity (publications, abstracts).

  • Excellent scientific writing and communication skills.

  • Leadership presence and ability to defend clinical plans in governance settings.

  • Adaptable to fast-paced, changing environments.

  • Effective in cross-functional, matrixed team leadership and alignment.

  • Passionate about oncology science and improving patient outcomes.
    TealPfizer


Preferred Qualifications

  • Strong leadership presence and ability to collaborate effectively with clinical and scientific peers.

  • Team-oriented, both as a leader and contributor.

  • Globally minded and capable of navigating diverse cultures, backgrounds, and geographies effectively.
    Teal


Compensation & Benefits

  • Base Salary Range (USD): $219,800 – $366,400 annually.

  • Performance Bonus: Target of 25% of base salary via Pfizer’s Global Performance Plan.

  • Long-Term Incentives: Eligibility for share-based programs.

  • Benefits Include:

    • 401(k) plan with matching and additional company contributions

    • Paid time off (vacation, holidays, personal days)

    • Paid caregiver/parental and medical leave

    • Health coverage (medical, prescription drug, dental, vision)

  • Relocation Support: May be available depending on business needs and eligibility.
    TealEchoJobs.io


Compliance & Legal

  • Under the Sunshine Act, reimbursements for recruiting expenses for licensed physicians could be considered reportable transfers of value. If you incur reimbursed recruiting expenses, your information may be publicly disclosed. Contact your Talent Acquisition representative for details.
    EchoJobs.io

  • Pfizer is an Equal Opportunity Employer, adhering to nondiscrimination and employment eligibility laws (including E-Verify).
    Pfizer


Summary Table

Category

Details

Role

Global Development Lead, Medical Director (Oncology Early Development)

Locations

Multiple U.S. sites (e.g., La Jolla, New York, Cambridge)

Core Focus

Early-stage oncology clinical development (F1H → Proof-of-Concept)

Min Qualifications

MD or MD‑PhD, industry experience, board cert., leadership, scientific output

Bonus & Incentives

25% bonus target, share-based incentive eligibility

Benefits

Comprehensive health, retirement, leave, relocation assistance

Legal Note

Sunshine Act compliance, EEO policies