Job Title: Expert – Science & Technology (Oligonucleotides/Peptide Therapeutics)
Job ID: REQ-10069227
Location: Genome Valley, Hyderabad, India
Department: Global Analytical R&D, Technical Research & Development (TRD), Global Drug Development (GDD)
Employment Type: Full-time, Regular
Posted Date: January 19, 2026
Novartis is a global healthcare leader dedicated to developing innovative, patient-centric therapies that improve and extend lives. The Global Analytical R&D team, spanning four countries, drives the transformation of molecules into medicines by integrating analytical science with clinical performance. This role is part of the Technical Research and Development Organization (TRD) within GDD at Genome Valley, Hyderabad.
The Expert – Science & Technology (Oligonucleotides/Peptide Therapeutics) will lead analytical development initiatives for novel oligonucleotide and peptide therapeutics. You will perform method feasibility studies, develop and validate robust analytical methodologies, and support laboratory operations with adherence to global quality and regulatory standards.
This position requires deep expertise in chromatography and mass spectrometry applied to complex biological molecules, coupled with strong scientific judgment and operational excellence.
Develop, validate, and transfer analytical methods for oligonucleotide and peptide therapeutics, including chromatography (RP, IEX, HILIC) and mass spectrometry-based approaches.
Plan, execute, and document scientific experiments, including method development, validation, stability studies, formulation analytics, and release testing.
Maintain and submit raw data using appropriate data systems (e.g., LIMS), ensuring good documentation practices (GDP) and good laboratory practices (GLP).
Analyze results, support investigations of deviations, OOX events, change controls, and troubleshoot analytical issues.
Manage laboratory resources including chemicals, reagents, consumables, columns, glassware, and ensure efficient laboratory operations.
Implement and maintain lean, sustainable, and environmentally responsible laboratory practices.
Meet Key Quality Indicators (KQIs) and Key Performance Indicators (KPIs) for all assigned activities.
Support internal and external audits with zero critical findings.
Actively contribute to team and organizational goals, collaborating across boundaries.
Adhere to SOPs, GMP, GLP, QM, HSE, ISRM, and Novartis guidelines.
Required:
PhD in Analytical Chemistry or equivalent with 1–3 years of relevant pharmaceutical experience, OR M.Pharm/M.Sc. with minimum 8 years of analytical development experience.
Strong expertise in chromatography techniques (RP, IEX, HILIC).
GMP experience and knowledge of regulatory expectations.
Proficiency in scientific documentation, reporting, and presentation.
Competency in software and laboratory tools, including LIMS, Office Suite, and chromatography data systems (e.g., Chromeleon).
Preferred:
Experience with mass spectrometry for qualitative and quantitative analysis of biological molecules.
Participation in scientific exchange groups or collaborations within Novartis.
Opportunity to work with cutting-edge oligonucleotide and peptide therapeutics in a globally recognized R&D organization.
Exposure to advanced analytical technologies and method development processes.
Supportive, inclusive, and collaborative work environment focused on professional growth.
Comprehensive benefits covering health, well-being, career development, and work-life balance.
Learn more about Novartis culture and strategy: Novartis People & Culture
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