Job Title: Director – Neuroscience
Location: Indianapolis, Indiana, United States / Boston, Massachusetts, United States
Category: Research & Development / Neuroscience / Preclinical Drug Development
Job Type: Full-Time, Regular
Job ID: R-91461
Company Overview:
Lilly is a global healthcare leader headquartered in Indianapolis, Indiana, dedicated to improving patient lives through innovative medicines. Our multidisciplinary teams advance drug discovery, neuroscience research, and patient care while actively contributing to communities worldwide.
Role Overview:
We are seeking a highly motivated Director – Neuroscience to lead the Psychiatry, Pain, and Neuronal Health Team within Lilly’s Neuroscience Discovery Group. This role is ideal for a visionary laboratory leader with deep expertise in neuroscience, neurodevelopment, and neuronal plasticity. The successful candidate will guide cross-functional teams, develop preclinical biomarkers, and drive translational early-phase research across psychiatric and neurological disorders.
Key Responsibilities:
1. Leadership & Team Management:
Supervise a team of dedicated laboratory neuroscientists.
Lead cross-functional teams during preclinical drug development phases.
Mentor, coach, and develop laboratory staff and scientific talent.
2. Preclinical & Translational Research:
Identify, develop, and implement innovative approaches to enhance understanding of psychiatric and neurological disease biology.
Develop and translate preclinical in vivo biomarker assays (e.g., EEG) for early clinical development.
Provide robust, actionable data to support decision-making in novel neuroscience drug discovery.
3. Scientific Communication & Collaboration:
Present scientific findings to leadership, decision-makers, and cross-functional teams in a clear and compelling manner.
Collaborate across Lilly research sites and geographies to integrate translational and preclinical insights.
Contribute to regulatory documents and support investigational submissions.
Basic Qualifications:
Ph.D. in Biology, Biochemistry, Neuroscience, Neurophysiology, or related discipline with 10+ years of industry or academic experience beyond postdoctoral training.
OR
Master’s degree in Neuroscience, Neurophysiology, or related field with 20+ years of industry or academic experience, including laboratory leadership and discovery project management through preclinical development.
Preferred Skills & Competencies:
Strong understanding of pharmacology and measures of target engagement (ex vivo or in vivo) to inform human dose projections.
Proven ability to lead cross-functional teams and translate preclinical biomarkers into clinical development strategies.
Experience preparing scientific documents for regulatory filings.
Demonstrated track record of neuroscience research with peer-reviewed publications.
Excellent communication, presentation, and collaborative skills.
Additional Information:
Travel: 20–30%
On-site at Lilly Corporate Center, Indianapolis, IN and/or Lilly Seaport Innovation Center, Boston, MA
Compensation & Benefits:
Salary range: $144,000 – $250,800 depending on experience and education.
Eligible for company bonus based on performance.
Comprehensive benefits including 401(k), pension, medical, dental, vision, flexible spending accounts, life insurance, paid leave, and wellness programs.
Equal Opportunity & Inclusion:
Lilly is an EEO employer committed to providing equal opportunities and supporting individuals with disabilities in the workforce.
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