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Clinical Genomics Variant Scientist

Ucla Health
UCLA Health
0-2 years
$105,700 – $234,500
10 Jan. 22, 2026
Job Description
Job Type: Full Time Education: B.Sc/M.Sc/M.Pharma/B.Pharma/Life Sciences Skills: Causality Assessment, Clinical SAS Programming, Communication Skills, CPC Certified, GCP guidelines, ICD-10 CM Codes, CPT-Codes, HCPCS Codes, ICD-10 CM, CPT, HCPCS Coding, ICH guidelines, ICSR Case Processing, Interpersonal Skill, Labelling Assessment, MedDRA Coding, Medical Billing, Medical Coding, Medical Terminology, Narrative Writing, Research & Development, Technical Skill, Triage of ICSRs, WHO DD Coding

Job Title: Clinical Genomics Variant Scientist

Location: Los Angeles, CA, USA
Department: Molecular Diagnostics Laboratory
Work Schedule: Monday – Friday, 8:00 AM – 5:00 PM
Employment Type: Full-Time, Career Staff
Salary Range: $105,700 – $234,500 annually

Role Overview:
UCLA Health is seeking an experienced Clinical Genomics Variant Scientist to join the Molecular Diagnostics Laboratory. In this key role, you will curate and interpret germline and somatic variants, prepare high-quality clinical reports, and contribute to precision medicine efforts across the UCLA Health network. This role involves collaboration with clinicians, genetic counselors, and laboratory staff to ensure accurate, timely, and clinically relevant results from exome and targeted cancer sequencing assays.

Key Responsibilities:

  • Review and assess patient clinical notes alongside sequencing data from high-complexity molecular assays, including Clinical Exome Sequencing, Solid Tumor Panels, and Hematologic Malignancy Panels.

  • Perform variant curation and interpretation using established guidelines and evidence-based resources.

  • Draft, review, and refine clinical reports, ensuring accuracy, clarity, and clinical relevance.

  • Develop and maintain SOPs for variant curation, interpretation, and reclassification workflows.

  • Submit curated variants to public databases (e.g., ClinVar) and contribute to quality improvement initiatives.

  • Collaborate with cross-functional teams to support accurate and timely reporting.

  • Participate in clinical research projects and support implementation of new molecular diagnostic assays.

Qualifications & Experience:

  • Advanced degree (MS, PhD, or equivalent) in Genetics, Molecular Biology, Bioinformatics, or related field.

  • Hands-on experience with germline and somatic variant curation and interpretation.

  • Familiarity with Clinical Exome Sequencing, Solid Tumor Panels, and Hematologic Malignancy Sequencing Panels.

  • Experience drafting clinical reports for molecular diagnostic testing.

  • Knowledge of variant databases and submission processes (e.g., ClinVar).

  • Strong communication, collaboration, and problem-solving skills.

Why Join UCLA Health:
This role offers the opportunity to advance precision medicine, directly impacting patient care while contributing to research and development of innovative molecular diagnostic assays. UCLA Health provides a supportive environment with resources for professional growth and continuous learning.

Equal Opportunity Statement:
UCLA Health is an Equal Opportunity Employer and encourages applications from candidates of all backgrounds, including individuals with disabilities and veterans.