Job Title:
Associate Scientific Director, Translational Quantitative Pharmacology
📍 Location: Mumbai, Maharashtra, India
🕒 Job Type: Full-time
🔢 Job ID: 290678
Company Overview
At our company, we are curious minds driven by science and innovation to improve healthcare, life sciences, and electronics. We embrace diversity and inclusion, supporting our people to develop and grow while making a real impact on patients, customers, and the planet.
🌍 Global Presence: Operations across 6 continents
🏥 Healthcare Mission: Help create, improve, and prolong lives through intelligent devices, medicines, and technologies — focusing on Oncology, Neurology, and Fertility
Role Purpose
The Associate Scientific Director, Translational Quantitative Pharmacology (TQP) will be part of the Quantitative Pharmacology (QP) group within Clinical Measurement Sciences (CMS).
This scientific and cross-functional leadership role will:
Develop and execute Model-Informed Drug Development (MIDD) strategies
Oversee internal and external TQP activities (including CROs)
Drive innovation in mechanism-based PK/PD modeling, QSP, and PBPK
Influence decisions across discovery to early clinical development
Key Responsibilities
🔬 Scientific Leadership
Independently contribute to and advance the science of TQP
Mentor and guide junior scientists in modeling and simulation
Lead PK/PD model development from lead optimization to clinical PoC
📊 Modeling & Simulation
Design and analyze preclinical PK/PD experiments
Conduct human PK and DDI predictions
Apply models to predict FIM (First-in-Man) dosing
Use models to interpret and quantify toxicological signals (hepatic, cardiac, renal, dermal)
Utilize commercial tools or develop internal models for therapeutic index assessments
🤝 Cross-functional Collaboration
Interface with:
Research Units: Oncology, Neurology & Immunology
Functions: Clinical Pharmacology, Biostatistics, DMPK, Toxicology, Biomarkers, Pharmacometrics, Data Sciences
Present modeling outcomes at internal/external meetings and regulatory filings
Contribute to regulatory documentation (e.g., IBs, INDs, CTDs)
Strategic Impact
Provide scientific and technical expertise to implement and promote MIDD strategy
Contribute to decision-making tools that ensure the right dose to the right patient
Collaboration & Representation
🔄 Internal Interfaces:
Project teams across therapeutic areas
CMS and QP teams
🌐 External Interfaces:
Represent company in IQ consortia, academic collaborations
Present at conferences, publish in peer-reviewed journals
Candidate Profile
🎓 Education & Experience
Ph.D. in:
Pharmacokinetics, Pharmaceutical Sciences
Biomedical/Chemical Engineering
Applied Mathematics or related field
Minimum 5 years of industry or academic experience in TQP, QSP, or related disciplines
Fluent in English
🧪 Technical Expertise
Quantitative Systems Pharmacology (QSP)
Mechanism-based PK/PD modeling
Software/tools: MATLAB/SimBiology, NONMEM, R, Monolix
PBPK modeling: Simcyp, GastroPlus, MATLAB
Toxicology modeling tools (e.g., DILIsym, RenaSym) – highly desirable
Understanding of immunology, oncology, or immuno-oncology
💼 Professional Skills
Strong ability to mentor and educate across teams
Capability to translate biology into multi-scale models
Excellent communication and presentation skills
Independent and collaborative working style
Demonstrated publication record in peer-reviewed journals or conferences
What We Offer
💰 Financial Benefits
Generous 401(k) with company matching and discretionary contributions
Tax-advantaged accounts
Company-provided life and accident insurance
❤️ Health & Wellness
Medical, dental, vision plans
Virtual healthcare & Telehealth
Free counseling sessions (EAP)
💼 Voluntary Benefits
Additional insurance coverage options
Discount programs (auto, home, pet, personal loans)
🧘 Work-Life Support
Generous paid time off
Back-up day care services
Education assistance
Supportive, flexible work culture
Recruitment Process
Apply Online
Screening & Selection
Interview (Phone/Video/Onsite)
Mutual Agreement & Offer
Onboarding Begins – Work Your Magic!
Equal Opportunity Statement
We are proud to be an Equal Employment Opportunity (EEO) employer. We do not discriminate on any protected basis and encourage applicants from all backgrounds to apply.
Fraud Alert
⚠️ Beware of fraudulent job offers claiming to represent our company. If unsure, please verify through our official careers page.
How to Apply
👉 Apply Now via our Careers Portal
🔎 Not ready yet? Join our Talent Zone to stay informed about future opportunities.
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Brussels |Flemish Brabant :
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Canada |Ontario :
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