Job Title:
Sr Medical Director / Global Medical Indication Lead – Rheumatology (Client Dedicated)
Location:
Remote, United States (Preferred: Eastern or Central Time Zones)
Job ID: R-01291332
Job Type: Full-time
Remote Status: Fully Remote
Work Schedule: Standard (Mon–Fri)
Company Overview:
At Thermo Fisher Scientific, through our PPD® clinical research portfolio, we are a leading global CRO dedicated to accelerating drug development and clinical innovation. Join a team that is helping to make the world healthier, cleaner, and safer—impacting lives through science and discovery across 100+ countries.
Position Summary:
As the Senior Medical Director / Global Medical Indication Lead – Rheumatology, you will lead the medical strategy and clinical development plans for client-dedicated rheumatology assets. You’ll drive cross-functional collaboration to translate the Target Product Profile (TPP) into actionable clinical strategy, ensuring regulatory compliance, scientific integrity, and strategic vision across all phases of drug development.
Key Responsibilities:
Strategic Clinical Leadership:
Lead the medical strategy and own the Clinical Development Plan (CDP) for assigned rheumatology assets.
Translate TPP into study design that meets time, quality, and budget goals.
Provide continuous strategic medical insight from early through late-stage clinical development.
Guide cross-functional collaboration with study teams, regulatory, safety, biostats, and clinical operations.
Team & Oversight:
Line manage and mentor global clinical trial physicians; set standards for high-quality medical input.
Ensure consistency and harmonization across studies within the indication.
Oversee real-time medical aspects of all indication studies and escalate issues to leadership as necessary.
Stakeholder & Regulatory Collaboration:
Serve as medical liaison with external stakeholders such as IRBs, regulatory authorities, and investigators.
Lead advisory boards and communicate key data across stakeholders and teams.
Ensure compliance with ICH/GCP, FDA, and internal company regulations.
Required Qualifications:
Education:
MD or equivalent degree required.
Specialty board certification in Rheumatology highly preferred.
Formal specialty training or fellowship required.
Experience:
Minimum 3–5 years experience in clinical development within pharma/biotech.
Demonstrated end-to-end involvement in drug development (Phase I–III/registration).
Experience leading global cross-functional teams and developing CDPs for immune/inflammatory diseases.
Knowledge, Skills, and Abilities:
Expertise in clinical trial design, medical safety evaluation, and data interpretation.
Strong leadership with the ability to coach and influence across matrix teams.
Excellent written and spoken English.
Skilled in stakeholder communication, negotiation, and conflict resolution.
Strong problem-solving orientation with a proactive mindset.
Ability to travel 10–20%, including international travel if needed.
Work Environment & Physical Requirements:
Office-based or remote with use of standard office equipment.
Must be able to remain in a stationary position for extended periods.
Occasional lifting of up to 20 lbs (e.g., laptop, documents).
Regular international and domestic travel as required by clinical or strategic needs.
Compensation & Benefits:
Estimated Salary Range (North Carolina): $200,000 – $278,900/year
Eligible for annual performance-based bonus.
Comprehensive Total Rewards package including:
Medical, dental, vision plans
401(k) retirement plan with match
Paid parental leave & PTO
Life and disability insurance
Tuition reimbursement
Employee Stock Purchase Plan (ESPP)
For more information: Thermo Fisher Total Rewards
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