Location: Global
Department: Formulation Development
Experience Required: 5–7+ Years (depending on degree)
Industry: Pharmaceuticals / Biotechnology
The Senior Scientist I (Formulations) plays a key role in early- and late-stage drug product development, with a focus on small-molecule oral solid dosage forms. This role is responsible for formulation design, process development, optimization, scale-up, and technology transfer. The position supports clinical trial material (CTM) manufacturing and collaborates with internal and external teams across fast-paced programs.
The ideal candidate brings strong technical expertise, problem-solving capability, hands-on experience in high-potency labs, and the ability to lead by example while communicating effectively with cross-functional stakeholders and senior leadership.
Develop oral solid dosage formulations for oncology products using modern formulation technologies.
Design lab-scale and scale-up manufacturing processes for small-molecule oral dosage forms.
Identify critical quality attributes (CQAs) and critical process parameters (CPPs), implementing robust process controls.
Conduct troubleshooting for formulation and process challenges.
Apply systematic approaches to excipient selection, vehicle optimization, and evaluation of enabling technologies.
Utilize statistical design of experiments (DoE) to refine formulations and scale-up processes.
Operate in a high-potency laboratory environment using PAPR and required safety procedures.
Work with advanced formulation technologies such as solid dispersion, lipid-based systems, microemulsions, and oral liquids.
Support non-clinical, early-stage, and late-stage development programs.
Participate in internal and external project teams.
Contribute to the preparation and review of CMC and regulatory documentation.
Present technical data and development updates to leadership teams.
Support technology transfer, process validation, and commercialization activities.
This role does not include direct supervisory responsibilities.
BS/BA in Pharmaceutics, Pharmaceutical Sciences, Bioengineering, Biophysics, or Chemical Engineering with 7+ years of relevant experience, or
MS/MA in related fields with 5+ years of relevant experience, or
PhD in related fields with 0–2+ years of relevant experience, or
Equivalent combination of education and experience.
Experience within the Pharmaceutical/Biotech industry preferred.
Proven experience in solid oral drug product formulation development is required.
Hands-on expertise in:
High shear granulation
Roller compaction
Direct compression
Aqueous and solvent-based coating
Experience with statistical tools for experimental design preferred.
Background in controlled-release or advanced delivery systems is a plus.
Experience with analytical instrumentation such as HPLC, FTIR, TGA, and DSC desirable.
Strong understanding of formulation development and scale-up of oral solid dosage forms.
Working knowledge of GMP, ICH guidelines, and drug development phases.
Proficiency in MS Office and scientific software applications.
Strong analytical, verbal, and written communication skills.
Ability to develop new methodologies and implement best practices.
Demonstrated creativity, technical depth, and cross-disciplinary understanding.
Ability to evaluate complex technical challenges and recommend innovative solutions.
Work involves complex technical problems requiring in-depth analysis.
Exercises judgment within broadly defined practices and policies.
Applies professional concepts to develop practical, effective solutions.
Collaborates with technical experts across multiple disciplines.
Primarily office-based with laboratory collaboration as needed.
Up to 10% domestic/international travel may be required.
Base Salary Range:
USD $116,000 – $165,500 annually
(Adjusted based on geographic region, experience, skills, and internal equity.)
Total Rewards Package Includes:
Comprehensive medical, dental, and vision plans
401(k) with company contributions
Life and disability insurance
Flexible spending accounts
Annual bonus eligibility
Employee stock purchase plan and long-term incentives
15 vacation days (first year)
17 paid holidays, including a winter shutdown
Up to 10 sick days annually
We are an Equal Opportunity Employer and do not discriminate based on race, color, gender, age, national origin, religion, sexual orientation, gender identity, veteran status, disability, or any other protected category.
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