Position Title:
Senior Scientist – Research Computational Biology (ARIA)
Location: United States (Remote)
Job ID: R-227773
Category: Research
Work Type: Remote
Date Posted: October 14, 2025
Salary Range: USD 132,494 – 163,875
About Amgen
At Amgen, you’re part of something bigger — a shared mission to serve patients living with serious illnesses. Since 1980, Amgen has been a biotechnology leader focused on four therapeutic areas:
Oncology
Inflammation
General Medicine
Rare Disease
Our commitment to patients drives everything we do — from research and manufacturing to delivering innovative medicines that help people live longer, fuller, and happier lives.
Role Overview
The ARIA Computational Biology Team is seeking a talented Computational Biologist to advance Amgen’s therapeutic pipeline. You will combine expertise in data science and disease biology to accelerate the identification, prioritization, and validation of transformative therapeutic targets in a cross-functional research environment.
Key Responsibilities
Extract biological insights from multi-modal omics and screening data to characterize disease mechanisms, identify biomarkers, and test hypotheses.
Develop and apply computational platforms to discover, prioritize, and validate drug targets across diverse diseases and therapeutic modalities.
Collaborate closely with Amgen therapeutic area scientists on internal programs and external partnerships.
Partner with data science and IT teams to integrate computational tools into Amgen’s R&D platforms.
Basic Qualifications
Doctorate in Computational Biology, Bioinformatics, Data Science, or related discipline (post-doc experience preferred)
OR
Master’s degree + 3 years of relevant research experience
OR
Bachelor’s degree + 5 years of relevant research experience
Preferred Qualifications
Strong programming skills in Python, R, Linux/Unix; experience with cloud computing, HPC, and Git.
Proven record of creative computational strategy development for complex research challenges.
Expertise in single-cell omics data analysis and interpretation.
Excellent communication and presentation abilities for multidisciplinary audiences.
Background in cardiometabolic disease and/or immunology, especially in relation to single-cell data.
Experience using or fine-tuning transcriptional foundation models, LLMs, and biomedical knowledge graphs.
Familiarity with public data resources (DepMap, Human Cell Atlas, TCGA, GTEx, Tahoe-100M).
Experience deploying tools or pipelines via:
Interactive portals (e.g., RShiny apps)
Workflow management systems (e.g., Nextflow)
Agentic frameworks
What You Can Expect from Amgen
Amgen is committed to your professional growth and well-being. Our Total Rewards Plan includes:
Comprehensive benefits package – health, dental, vision, life, disability insurance
Retirement & Savings Plan with company contributions
Annual bonus or sales-based incentives (for applicable roles)
Stock-based long-term incentives
Award-winning time-off plans
Flexible work models – remote/hybrid options
Career development opportunities and continuous learning
Actual salary will vary based on skills, experience, and qualifications.
Diversity & Inclusion
Amgen fosters an inclusive, respectful environment that values diversity and ethical collaboration.
We are an Equal Opportunity Employer — all qualified applicants will receive consideration without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran status, or disability.
Reasonable accommodations will be provided for individuals with disabilities during the hiring process upon request.
How to Apply
Apply now to join Amgen’s mission of transforming the lives of patients while advancing your own career.
🔗 Apply at: careers.amgen.com
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