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Senior Research Associate

Syngene
2-5 years
INR 8 LPA – 18 LPA
Bangalore, India
1 June 23, 2026
Job Description
Job Type: Full Time Education: B.Sc/M.Sc/M.Pharma/B.Pharma/Life Sciences Skills: Analytical Characterization, Dissolution Testing, Experimental Design, GMP/cGMP Compliance, HPLC, HPLC Analysis, Pre-formulation Studies, Regulatory Filing Support, Root Cause Analysis (RCA), Technology Transfer, UPLC

Senior Research Associate – Translational Medicine (TM-TDDT)

Location: Bangalore, Karnataka, India
Company: Syngene International (Biocon Bristol Myers Squibb Research Center)
Department: Translational Medicine – TM-TDDT
Employment Type: Full-Time

Role Summary

The Senior Research Associate – Translational Medicine is responsible for executing preclinical and translational research studies that support late-stage drug development programs across oncology, immunology, and hematology-oncology therapeutic areas. The role focuses on mechanism-of-action studies, biomarker development, patient selection strategies, combination therapies, resistance mechanisms, and differentiation from existing standards of care.

This position works closely with Translational Scientists, Disease Area Leaders, and cross-functional research teams to generate high-quality scientific data that supports drug development, regulatory filings, and clinical decision-making.

Key Responsibilities

Translational Research & Drug Development

  • Execute preclinical studies supporting late-stage drug development programs.

  • Support translational medicine strategies for:

    • Biomarker Development

    • Patient Selection

    • Dose Optimization

    • Schedule Optimization

    • Combination Therapies

    • Resistance Mechanisms

    • Product Differentiation

  • Generate data to support internal and external translational research initiatives.

Preclinical Laboratory Research

  • Conduct laboratory experiments on BMS portfolio compounds.

  • Support:

    • Mechanism of Action Studies

    • Pharmacology Studies

    • Biomarker Research

    • Translational Research Programs

  • Deliver reproducible and scientifically robust data.

Cell Biology & Molecular Biology

  • Perform:

    • Mammalian Cell Culture

    • Primary Cell Isolation

    • Cell Transfection

    • Single Cell Cloning

  • Work with:

    • siRNA Technologies

    • CRISPR Gene Editing

    • TALEN Technologies

    • HDR Workflows

Gene Expression & Genomics

  • Conduct:

    • qRT-PCR

    • RNA Sequencing Support

    • Gene Expression Analysis

    • Epigenetic Studies

  • Support:

    • DNA Methylation Analysis

    • ChIP-Based Assays

    • Functional Genomics Research

Protein & Immunology Assays

  • Perform:

    • ELISA

    • MSD Assays

    • Luminex Assays

    • CBA Assays

    • Flow Cytometry

  • Conduct:

    • Cell Phenotyping

    • Immune Profiling

    • Biomarker Analysis

In Vivo Pharmacology

  • Design and execute:

    • Autoimmune Disease Models

    • Solid Tumor Models

    • Hematology-Oncology Models

  • Support efficacy and translational pharmacology studies.

Data Analysis & Reporting

  • Analyze experimental data and generate scientific interpretations.

  • Maintain detailed experimental records.

  • Prepare:

    • Technical Reports

    • Study Reports

    • Scientific Presentations

    • Nonclinical Pharmacology Reports

  • Support regulatory documentation and submissions.

Cross-Functional Collaboration

  • Collaborate with:

    • Translational Medicine Scientists

    • Disease Area Leaders

    • Early Development Teams

    • Research Collaborators

  • Facilitate seamless transfer of scientific information across programs.

Problem Solving & Innovation

  • Troubleshoot experimental challenges.

  • Identify technical risks and develop mitigation strategies.

  • Support continuous improvement of laboratory workflows and assay platforms.

Required Qualifications

Education

Master’s Degree in:

  • Biotechnology

  • Life Sciences

  • Immunology

  • Molecular Biology

  • Cell Biology

  • Pharmacology

  • Biochemistry

  • Biomedical Sciences

  • Related Discipline

Experience

Required Experience

  • Typically 2–5 Years of relevant experience in:

    • Translational Research

    • Immunology

    • Oncology

    • Hematology-Oncology

    • Drug Discovery Research