Senior Research Associate – Non-viral Delivery | Novo Nordisk, Lexington, USA
Job Summary:
Novo Nordisk is hiring a Senior Research Associate in Non-viral Delivery to join its Global Nucleic Acid Therapies unit in Lexington. This role focuses on designing, executing, and analyzing pre-clinical in vitro and ex vivo studies to support the development of RNA and gene therapies using the proprietary GalXC™ and GalXC-Plus™ technologies. The ideal candidate will bring strong experience in preclinical pharmacokinetics, drug discovery, and in vitro model development.
Key Responsibilities:
Conduct and analyze non-clinical in vitro and ex vivo pharmacokinetic/pharmacodynamic studies
Design experimental protocols for preclinical evaluations
Coordinate internal and external study execution aligned with drug development objectives
Improve and innovate in vitro models to support non-clinical studies
Interpret experimental data and communicate findings to stakeholders and regulatory bodies
Contribute to formal reports and regulatory documentation
Collaborate with cross-functional teams (in vivo, ex vivo, bioanalytical, formulation scientists)
Present scientific data within the Nucleic Acid Research Area and global project teams
Required Skills & Qualifications:
BS/BA in life sciences with 2+ years' relevant experience
OR Master’s with limited experience
OR High School Diploma with 10+ years' experience
Strong understanding of in vitro pharmacokinetics/pharmacodynamics
Familiarity with experimental design and in vitro model development
Proficiency in scientific communication and cross-functional collaboration
Understanding of drug discovery and target validation workflows
Desirable Skills:
PCR experience with in vitro and ex vivo samples
Experience with automation tools (Assist-Plus, ViaLab)
Fluorescence imaging and immunohistochemistry expertise
Cytokine storm assays using MSD or Luminex platforms
Perks & Benefits:
Work on cutting-edge RNA and gene therapy programs
Access to advanced tools, technologies, and global collaborations
Inclusive and diverse work culture
Opportunity for scientific and career growth
Competitive salary (not explicitly mentioned; based on experience)
Equal opportunity employer with accommodation support
Company Description:
Novo Nordisk is a global leader in healthcare and biotechnology innovation. Through its Global Nucleic Acid Therapies group, the company is pioneering RNA and gene therapies to address chronic and genetic diseases. The Lexington site plays a key role in early-stage research and development with state-of-the-art facilities and expert cross-functional teams.
Work Mode:
On-site – Lexington, United States
Call-to-Action:
If you’re passionate about scientific innovation in nucleic acid therapies, apply now to join Novo Nordisk’s Non-viral Delivery team in Lexington. Be part of a purpose-driven R&D organization revolutionizing medicine.
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