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Senior Principal Scientist, Clinical Research

10 years
$146,700.00 – $293,300.00
10 Sept. 9, 2025
Job Description
Job Type: Full Time Education: B.Sc/ M.Sc/ M.Pharm/ B.Pharm/ Life Sciences Skills: Causality Assessment, Clinical SAS Programming, Communication Skills, CPC Certified, GCP guidelines, ICD-10 CM Codes, CPT-Codes, HCPCS Codes, ICD-10 CM, CPT, HCPCS Coding, ICH guidelines, ICSR Case Processing, Interpersonal Skill, Labelling Assessment, MedDRA Coding, Medical Billing, Medical Coding, Medical Terminology, Narrative Writing, Research & Development, Technical Skill, Triage of ICSRs, WHO DD Coding

Senior Principal Clinical Research Scientist

Location: Sylmar, CA (Cardiac Rhythm Management Division)
Company: Abbott


About Abbott

Abbott is a global healthcare leader that helps people live more fully at all stages of life. Our portfolio of life-changing technologies spans diagnostics, medical devices, nutritionals, and branded generic medicines. With 114,000 colleagues across 160+ countries, we are committed to advancing health and well-being worldwide.


Why Work at Abbott

At Abbott, you’ll have the opportunity to:

  • Do meaningful work that impacts lives.

  • Grow your career in an international company.

  • Care for yourself and your family with exceptional benefits.

  • Be your true self and thrive in an inclusive culture.

Employee Benefits include:

  • Free medical coverage under the Health Investment Plan (HIP) PPO (starting next calendar year).

  • Excellent retirement savings plan with high employer contribution.

  • Tuition reimbursement, Freedom 2 Save student debt program, and FreeU education benefit.

  • Recognition as a Great Place to Work in multiple countries and one of Fortune’s Most Admired Companies.

  • Named one of the best companies for diversity, working mothers, female executives, and scientists.


The Opportunity

Abbott’s Cardiac Rhythm Management division is a global leader in technologies for treating heart arrhythmias.

As a Senior Principal Clinical Research Scientist, you will:

  • Serve as a leader on clinical trial design, clinical evaluations, risk management, strategy, and data analysis.

  • Author and manage clinical evaluation plans/reports, trial protocols, risk master lists, trial registrations, results postings, timelines, and scientific publications.

  • Lead study support groups and cross-functional teams to develop clinical strategies.

  • Interact with regulatory agencies and provide scientific direction to internal teams and clinical study sites.

  • Mentor junior clinical scientists.


Key Responsibilities

  • Provide scientific leadership and strategic advice on clinical evaluations, trial design, risk management, and data analysis.

  • Collaborate with cross-functional teams (Biostatistics, RA, Clinical Operations, Data Management, Safety, R&D, Marketing, Quality, Product Performance, Risk Management, etc.).

  • Develop and deliver clinical evaluation plans/reports, study protocols, and scientific discussions.

  • Interpret and evaluate clinical/scientific/risk data and literature for product applications.

  • Present scientific results at industry meetings, investigator meetings, and regulatory discussions.

  • Support regulatory submissions and agency communications.

  • Participate in audits and ensure compliance with corporate/divisional policies and quality system requirements.

  • Manage financial, budgetary, and legal aspects as assigned.


Required Qualifications

  • Bachelor’s degree in a related field (or equivalent combination of education and experience).

  • Minimum 10 years of experience, including at least 5 years in clinical trials, risk management, or clinical evaluations.

  • Comprehensive knowledge of clinical research processes, risk management, and regulatory frameworks.

  • Recognized as an expert across functions with deep understanding of business unit operations and cross-functional dependencies.

  • Strong analytical, problem-solving, and decision-making skills.

  • Ability to exercise judgment within broadly defined practices and policies.


Compensation

  • Base Pay Range: $146,700 – $293,300 (range may vary by location).


How to Apply

Abbott is an Equal Opportunity Employer, committed to diversity and inclusion.

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