Senior Principal Investigator

Syngene

10-12 years

Not Disclosed

Bangalore India

10 Jan. 21, 2026

Job Description

Job Type: Full Time Education: B.Sc/M.Sc/M.Pharma/B.Pharma/Life Sciences Skills: Causality Assessment, Clinical SAS Programming, Communication Skills, CPC Certified, GCP guidelines, ICD-10 CM Codes, CPT-Codes, HCPCS Codes, ICD-10 CM, CPT, HCPCS Coding, ICH guidelines, ICSR Case Processing, Interpersonal Skill, Labelling Assessment, MedDRA Coding, Medical Billing, Medical Coding, Medical Terminology, Narrative Writing, Research & Development, Technical Skill, Triage of ICSRs, WHO DD Coding

Job Title: Senior Principal Investigator – Process Chemistry
Location: Bangalore, Karnataka, India (PIN 560099)
Division: Dedicated Centre
Department: Chemical Development & API Supply, BBRC
Experience Required: 10–15 years in process chemistry, API development, and scale-up operations

Company Overview:
Syngene International Ltd., founded in 1993, is a global, innovation-driven discovery, development, and manufacturing organization providing integrated scientific services across pharmaceutical, biotechnology, nutrition, animal health, consumer goods, and specialty chemical industries. Syngene partners with global leaders such as Bristol-Myers Squibb, Baxter, Amgen, GSK, Merck KGaA, and Herbalife. With a 4,240-strong team of scientists, Syngene delivers innovative solutions to accelerate R&D productivity, reduce time-to-market, and optimize the cost of innovation.

Role Overview:
The Senior Principal Investigator (SPI) – Process Chemistry leads a team of process development scientists, overseeing scientific strategies, resource allocation, and execution of process chemistry projects. The SPI ensures high-quality research, process development, and scale-up for APIs and preclinical/clinical candidates while fostering scientific excellence and team development.

Key Responsibilities:

Leadership & Team Management:

Lead and mentor process development scientists to achieve project and management objectives efficiently.
Allocate resources and prioritize projects to optimize team productivity and scientific outcomes.
Provide visionary leadership to multiple project groups in process chemistry development and scale-up technologies.
Facilitate structured objective setting, performance appraisal, and career development within the team.
Promote a culture of scientific excellence, collaboration, and continuous improvement.

Scientific & Technical Oversight:

Lead process research and development for New Chemical Entities (NCEs) and API candidates.
Apply expertise in modern and classical organic chemistry to solve complex chemistry problems proactively.
Provide technical guidance, mentorship, and training to team members.
Support the Head of Process R&D in implementing research strategies and delivering high-quality outcomes.
Recommend and implement methods to improve efficiency, productivity, and innovation within the process chemistry function.

Project & Stakeholder Management:

Communicate research results, progress, and challenges effectively to management and stakeholders.
Ensure alignment of team objectives with organizational goals and project timelines.
Manage multiple projects in a matrix organization, ensuring compliance with quality, safety, and regulatory standards.

Educational Qualifications:

Ph.D. or Post-Doctoral degree in Organic Chemistry

Technical & Functional Skills:

Expertise in process chemistry, API process development, and scale-up technologies.
Proven project management experience in leading process chemistry teams.
Strong leadership skills with experience managing large, multidisciplinary scientific teams.
Experience working in a matrixed organization with multiple stakeholders and projects.

Behavioral & Leadership Skills:

Strategic and analytical thinking with advanced verbal and written communication.
Ability to motivate, inspire, and energize scientific teams.
High emotional intelligence and capability to manage matrixed teams and sub-functions effectively.

Why Join Syngene:

Lead high-impact process chemistry projects for globally recognized pharmaceutical clients.
Work in an innovative, dynamic, and collaborative environment with world-class scientific teams.
Drive scientific excellence while contributing to the development of APIs and clinical candidates.

Equal Opportunity Employer:
Syngene International Ltd. provides equal employment opportunities to all qualified individuals regardless of age, color, national origin, citizenship, disability, race, religion, gender, sexual orientation, gender identity, genetic information, marital status, veteran status, or any other legally protected characteristic. Reasonable accommodations are provided for qualified individuals with disabilities.

Apply Now to join Syngene as a Senior Principal Investigator – Process Chemistry in Bangalore and lead innovative process development initiatives in the pharmaceutical industry.

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Senior Principal Investigator

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