Job Title: Senior Principal Investigator
Job Category: Process Chemistry / API Development
Location: Bangalore, Karnataka, India
Experience Required: 10–15 Years in process development and scale-up of APIs in pharmaceutical or CRO environments
Job Type: Full-Time
Company Overview
Syngene International Ltd. is a global, innovation-driven contract research, development, and manufacturing organization offering integrated scientific services from early discovery to commercial supply. Syngene serves leading pharmaceutical, biotechnology, and specialty chemical companies worldwide, delivering solutions that accelerate drug development, improve R&D productivity, and reduce time-to-market.
Role Overview
The Senior Principal Investigator will lead process development teams and oversee scientific programs for New Chemical Entities (NCEs) and API scale-up projects. This leadership role combines strategic planning, team management, and hands-on technical guidance to ensure timely delivery of high-quality outcomes in chemical process development.
Key Responsibilities
Lead and mentor a team of process development scientists, ensuring efficient resource allocation and achievement of project milestones.
Provide strategic direction for process chemistry research, development, and scale-up technologies for preclinical and clinical candidates.
Communicate project progress, challenges, and scientific insights effectively to senior management and stakeholders.
Support Head of Process R&D in defining and executing research strategies.
Demonstrate advanced expertise in modern and classical organic chemistry, proactively solving complex process chemistry problems.
Implement methods to enhance team productivity and scientific output.
Manage performance appraisals, objective setting, and professional development of team members.
Drive cross-functional collaboration within matrixed teams to achieve organizational goals.
Educational Qualification
Ph.D. or Postdoctoral experience in Organic Chemistry
Technical Skills
Deep expertise in process chemistry, including development and scale-up of APIs and NCEs.
Strong project management capabilities for large, multi-disciplinary process chemistry teams.
Proven experience in matrix organization management and strategic planning.
Ability to visualize complex chemistry challenges and provide proactive solutions.
Behavioral Skills
Strategic and analytical thinking with strong problem-solving abilities.
Advanced verbal and written communication skills.
Strong leadership presence, capable of motivating and energizing teams.
High emotional intelligence and experience managing large, matrixed teams.
Syngene Values
All employees are expected to uphold Syngene’s core values: Excellence, Integrity, and Professionalism.
Equal Opportunity Employer
Syngene provides equal employment opportunities (EEO) to all candidates regardless of age, gender, race, religion, disability, or other protected characteristics. Reasonable accommodations are available for qualified individuals with disabilities.
This position is ideal for experienced process chemistry leaders seeking to drive innovation in API development while managing high-performing scientific teams in a global R&D environment.
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