Bbrc - Research Investigator - Cadd

0-2 years

Not Disclosed

Bangalore

10 Jan. 29, 2025

Job Description

Job Type: Full Time Education: B.Sc,M.Sc,B.Pharma,M.Pharma,LifeScience Graduates Skills: Causality Assessment, Clinical SAS Programming, Communication Skills, CPC Certified, GCP guidelines, ICD-10 CM Codes, CPT-Codes, HCPCS Codes, ICD-10 CM, CPT, HCPCS Coding, ICH guidelines, ICSR Case Processing, Interpersonal Skill, Labelling Assessment, MedDRA Coding, Medical Billing, Medical Coding, Medical Terminology, Narrative Writing, Research & Development, Technical Skill, Triage of ICSRs, WHO DD Coding

Job Title: Research Investigator – CADD

Date: 15 Jan 2025
Job Location: Bangalore
Pay Grade: 7-I
Years of Experience: 0 - 2 Years

About Syngene

Syngene International Ltd., established in 1993, is a global contract research, development, and manufacturing organization (CRDMO) serving the pharmaceutical, biotechnology, nutrition, animal health, consumer goods, and specialty chemical industries. Syngene collaborates with global leaders such as Bristol-Myers Squibb, Baxter, Amgen, GSK, Merck KGaA, and Herbalife. With a strong team of over 4,240 scientists, Syngene is committed to accelerating scientific innovation, enhancing R&D productivity, and reducing the time and cost of drug discovery.

Job Overview

The Research Investigator – CADD (Computer-Aided Drug Design) will be part of the Medicinal Chemistry (MedChem) CADD team, providing computational chemistry expertise to support drug discovery programs. The role involves collaborating with interdisciplinary teams, utilizing computational techniques to drive structure-activity relationship (SAR) insights, and contributing to innovative drug design strategies.

Key Responsibilities

Provide computational chemistry support to drug discovery programs.
Analyze structure-activity relationships (SAR) across in vitro biology, DMPK, structural, and computational datasets.
Collaborate closely with medicinal chemists to drive hypothesis-driven compound design.
Utilize ligand- and structure-based computational approaches, including docking, pharmacophore modeling, and molecular dynamics simulations.
Identify and implement computational techniques tailored to specific project challenges.
Present research findings at CADD, chemistry, and project team meetings.
Stay up-to-date with relevant scientific literature and emerging trends in computational chemistry.
Maintain accurate records of research activities and ensure data integrity.

Required Qualifications & Experience

Education:

PhD in Computational Chemistry or Computer-Aided Drug Design (CADD).

Experience:

0-5 years of experience in pharmaceutical or biotechnology industries.

Technical Skills

Strong expertise in structure-based and ligand-based computational methods, including:
- Molecular mechanics and quantum mechanics
- Docking, pharmacophore modeling, and molecular dynamics simulations
- QM (Quantum Mechanics) calculations
Proficiency in statistical methods and physical organic chemistry.
Coding skills in Python and/or Unix Shell scripting.
Ability to collaborate with medicinal chemistry, biology, and DMPK scientists.
Experience in drug discovery within oncology, immunology, cardiovascular, or fibrosis research areas.

Behavioral & Functional Skills

Strong interpersonal and communication skills to work effectively within interdisciplinary teams.
Ability to ask questions, seek input, and understand the bigger picture.
Active listening and engagement with project stakeholders.
Willingness to offer support and collaborate with team members to solve complex challenges.

Equal Opportunity Employer Statement

Syngene is an equal opportunity employer committed to fostering an inclusive and diverse workplace. We prohibit discrimination based on age, color, nationality, citizenship status, disability, race, religion, gender, sexual orientation, gender identity, genetic information, marital status, veteran status, or any other protected characteristic. Syngene also provides reasonable accommodations for qualified individuals with disabilities.

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