Registered Nurse (RN) – Weekend Nights (Friday, Saturday & Sunday, 6 PM – 6 AM CST)
Location: Madison, Wisconsin, USA
Category: Patient Services
Job ID: 251323
Experience Required: 2–3 years of nursing experience
About the Role:
Join one of the world’s largest Clinical Research Organizations, with four Early Phase Clinical Research Units across the UK and US. We are seeking a Registered Nurse (RN) for a weekend night shift role in Madison, WI, to provide clinical care to healthy volunteer participants while supporting complex research protocols.
This position is full-time, on-site, and strictly scheduled for weekend nights: Friday, Saturday, and Sunday from 6 PM to 6 AM CST. You will gain hands-on experience across a variety of therapeutic areas and study designs, including first-in-human trials, ascending dose studies, food effect trials, and drug-drug interaction research.
As an RN in Phase 1 clinical trials, you will work closely with participants, maintain and expand your clinical expertise, and be part of innovative research that contributes directly to patient care worldwide.
Key Responsibilities:
Deliver high-quality clinical care using nursing skills, knowledge, and professional judgment
Accurately perform vital signs assessments: blood pressure, pulse, respiratory rate, temperature, weight, and venipuncture
Prepare and record ECGs and Holters accurately
Collect, process, and distribute biological samples according to study protocols
Monitor participant meals for dietary compliance
Assist in preparing clinical rooms and medical equipment
Support screening and other study-related procedures as needed
Maintain a safe, clean, and organized study environment
Perform additional duties as assigned to support clinical research
Qualifications & Requirements:
Associate or Bachelor of Science degree in Nursing (BSN/ADN) with current state licensure
CPR/AED certified; ACLS certification required
2–3 years of clinical nursing experience; additional experience may substitute for education requirements
Comfortable working in a fast-paced, protocol-driven environment where strict timelines must be met
Strong teamwork, adaptability, and problem-solving skills
Proficiency with electronic data collection and technology-based clinical tools
Physical & Work Requirements:
Ability to work upright or stationary for 6–8 hours per shift
Repetitive hand movements required to operate lab and clinical equipment
Occasional crouching, stooping, bending, or twisting
Ability to lift and carry objects up to 15–20 lbs
Flexibility to work weekend nights consistently
Benefits:
Eligible full-time or part-time employees (20+ hours/week) receive comprehensive benefits, including:
Medical, Dental, Vision, Life, and STD/LTD insurance
401(k) retirement plan
Paid Time Off (PTO)
Employee recognition programs
Access to Employee Resource Groups (ERGs)
Why Join Us:
This is a unique opportunity for experienced nurses to contribute to the earliest stages of clinical drug development while maintaining direct patient care responsibilities. You will gain exposure to cutting-edge therapies, advance your clinical skills, and make a meaningful impact on patient health globally.
Apply today to join our Phase 1 clinical research team in Madison, WI, for weekend night shifts.
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