Project Consultant (Clinical Pharmacology and Pharmacometrics Lead)
Company: Sia Partners
Location: Remote
Type: Contract (Exempt Contractor)
Level: Mid-Senior
Project Length: 12 months (with potential extension)
Compensation: Approximately $205k per year
About Sia Partners
Sia Partners is a next-generation management consulting firm that integrates AI and design capabilities with traditional consulting, delivering exceptional value to our clients. With a team of 3,000 consultants across 19 countries, we anticipate $420 million in revenue this fiscal year. Our global reach spans over 30 sectors, and through our Consulting for Good approach, we aim to develop innovative CSR solutions that drive sustainability and profitable transformation.
Job Description
We are seeking a Clinical Pharmacology and Pharmacometrics Lead to join our team as a contractor. Reporting to the Head of Clinical Pharmacology and Pharmacometrics, you will be responsible for leading the development of computational approaches for high-priority projects, focusing on model-informed drug development strategies. This role involves collaboration with various stakeholders, building partnerships with academic and CRO partners, and leading technology initiatives to enhance our simulation platform.
Key Responsibilities
Provide strategic leadership in Clinical Pharmacology and Pharmacometrics for late-stage and early-stage assets, particularly in infectious diseases such as Tuberculosis and Malaria.
Develop advanced models of drug exposure, biomarker response, and disease progression to facilitate informed drug development decisions.
Collaborate with internal and external stakeholders, offering expertise in modeling, data science, visualization, and data analytics.
Serve as Study Director and Clinical PK Scientist for infectious diseases programs.
Contribute to regulatory documents and engage in regulatory interactions.
Assess clinical study feasibility and provide input on clinical protocol design.
Execute and manage Pharmacometrics and Modeling & Simulation (M&S) plans, reporting results to support clinical development milestones.
Integrate data from various compounds across development programs to inform strategic decisions.
Represent the department in cross-functional teams, promoting development opportunities.
Mentor junior Clinical Pharmacology scientists and promote a culture of scientific excellence.
Support project milestones in discovery and development using mathematical modeling and simulation tools, including PK/PK-PD and drug-drug interaction evaluations.
Demonstrate proficiency in Model-Informed Drug Development (MIDD) to enhance decision-making.
Utilize advanced data analysis techniques to leverage diverse datasets for relevant disease biology models.
Qualifications
Education: PhD in engineering, math, computer science, pharmaceutical sciences, or a related quantitative field.
Experience: Minimum of 10 years in a quantitative discipline, with a strong background in PK-PD, QSP, PBPK, and DMPK modeling.
Technical Skills: Proficient in high-performance computing, software such as Matlab, R, NONMEM, Monolix, SimCYP, PK-SIM, GastroPlus, and Phoenix.
Communication: Excellent ability to convey complex technical ideas to diverse audiences.
Project Management: Strong organizational skills with the ability to handle multiple priorities in a fast-paced environment.
Interpersonal Skills: Strong collaboration and customer service skills.
Additional Information
Sia Partners does not intend to pursue employment with applicants requiring visa sponsorship.
Benefits
Statutory Time Off – Sick Leave
Medical, Dental, Vision: Eligible for Purchase Option
401(k) Participation: Eligible after one month, with matching and 100% vesting from day one.
Our Commitment to Diversity
Diversity, equity, inclusion, and belonging are core to Sia Partners' culture. We promote an environment where all individuals can thrive, and our global DEIB@Sia Partners network drives progress across various areas, including gender equality, race, and disabilities.
Sia Partners is an equal opportunity employer. Employment decisions are based solely on performance, competence, and business needs.
To learn more about our mission and values, please visit our website.
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