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Principal Clinical Programmer (Rave + Custom Functions)

5-10 years
Not Disclosed
10 July 30, 2025
Job Description
Job Type: Remote Education: B.Sc./M.Sc/B.Pharm/M.Pharm/Life Science Skills: Causality Assessment, Clinical SAS Programming, Communication Skills, CPC Certified, GCP guidelines, ICD-10 CM Codes, CPT-Codes, HCPCS Codes, ICD-10 CM, CPT, HCPCS Coding, ICH guidelines, ICSR Case Processing, Interpersonal Skill, Labelling Assessment, MedDRA Coding, Medical Billing, Medical Coding, Medical Terminology, Narrative Writing, Research & Development, Technical Skill, Triage of ICSRs, WHO DD Coding

 

Principal Clinical Programmer (Rave + Custom Functions) – Syneos Health, Hyderabad [Hybrid]

Job Summary:

Syneos Health is actively hiring a Principal Clinical Programmer with advanced skills in Medidata Rave and Custom Functions for a hybrid role in Hyderabad. This role will lead programming activities across multiple studies or clinical programs, provide oversight and mentorship to junior programmers, and manage clinical data programming workflows using cutting-edge tools. You will also play a key role in system integration, troubleshooting, custom development, and sponsor engagement.


Key Responsibilities:

  • Design, develop, and validate clinical programming deliverables using Medidata Rave and other EDC platforms

  • Lead end-to-end programming activities and manage multiple concurrent clinical studies

  • Generate annotated CRFs, edit checks, import/export specs, listings, and custom reports

  • Lead system integrations, UAT, and technical support for hosted clinical applications

  • Review and approve study budgets, project scopes, and vendor deliverables

  • Oversee application vendor SLAs and support escalations and upgrades

  • Mentor and guide junior programmers and lead programmers within assigned projects

  • Support sponsor audits, bid defenses, and regulatory compliance activities

  • Monitor project-level metrics and identify resource needs or timeline risks

  • Lead cross-functional discussions and collaborate with global teams


Required Skills & Qualifications:

  • Bachelor’s degree in Life Sciences or related field (Master’s preferred)

  • Proven experience with end-to-end clinical programming in Rave EDC

  • Expertise in Custom Functions programming

  • Prior experience as programming lead on large-scale studies or programs

  • Proficiency in PL/SQL, SAS, C#, or VB preferred

  • Strong written and verbal communication skills

  • Proven ability to work in matrix-based, cross-functional teams

  • Experience with application validation and regulatory audit processes

  • Willingness to travel up to 25% if required


Perks & Benefits:

  • Hybrid work model (Hyderabad office)

  • Competitive salary (not specified in the listing)

  • Career development and technical training

  • Global exposure across 110 countries

  • Inclusive “Total Self” culture focused on diversity and belonging

  • Comprehensive health and wellness programs

  • Recognition and peer support initiatives


Company Overview:

Syneos Health is a global leader in biopharmaceutical solutions, delivering full-service clinical development, medical affairs, and commercialization. The company has supported 94% of all novel FDA-approved drugs and operates across 110 countries with a mission to simplify and accelerate healthcare innovation. Its technology-driven and inclusive culture empowers employees to deliver better health outcomes globally.


Work Mode: Hybrid (Hyderabad, India)
Experience Level: Senior (5–10+ years preferred)
Salary Range: Not specified in the job description


Call to Action:

Ready to lead innovative clinical programming at a global biopharma leader? Apply now and be part of Syneos Health’s transformative journey in clinical data excellence.