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Clinical Trial Manager I / Clinical Trial Manager Ii (Ctm I / Ctm Ii)

Syneos Health
Syneos Health
6-10 years
preferred by company
Remote, India, India
1 May 13, 2026
Job Description
Job Type: Full Time Education: B.Sc/M.Sc/M.Pharma/B.Pharma/Life Sciences Skills: ICH guidelines, ICSR Case Processing, Interpersonal Skill, Labelling Assessment, MedDRA Coding

Job Title: Clinical Trial Manager I / Clinical Trial Manager II (CTM I / CTM II)

Location: India (Remote / Client-Based)
Job Type: Full-Time
Experience Required: 6–10+ Years Overall, Including Minimum 2+ Years as Clinical Trial Manager (Freshers are not eligible)
Industry: Clinical Research / CRO / Clinical Operations / Pharmaceuticals / Biotechnology / Life Sciences
Department: Clinical Trial Management / Clinical Operations / Global Study Delivery

About the Role
We are seeking an experienced and highly strategic Clinical Trial Manager I / Clinical Trial Manager II (CTM I / CTM II) to lead global clinical trial delivery, site management oversight, risk-based monitoring governance, vendor coordination, and cross-functional operational execution. This leadership role is ideal for professionals with expertise in clinical trial management, site oversight, CRA team leadership, central monitoring, risk management, GCP compliance, and global clinical operations.

The ideal candidate will drive end-to-end clinical trial management activities from post-site activation through database lock and study closeout, ensuring operational excellence, patient safety, protocol compliance, and sponsor satisfaction.

This opportunity is highly suited for experienced clinical operations professionals ready to lead global study delivery in complex clinical development environments.

Key Responsibilities

Clinical Trial Leadership & Study Delivery Oversight

  • Lead end-to-end clinical trial management activities across assigned global clinical studies.
  • Oversee site management, clinical monitoring, and central monitoring execution from site activation through study closeout.
  • Ensure timely achievement of study milestones, enrollment goals, quality metrics, and operational deliverables.
  • Act as a key operational leader for sponsor-facing clinical study execution.

Site Oversight & Clinical Monitoring Governance

  • Provide oversight for:
    • CRA teams
    • Central Monitoring teams
    • Site management activities
    • Monitoring strategy execution
    • Site escalation management
  • Ensure monitoring activities align with protocol requirements, Clinical Monitoring Plans (CMP), Site Management Plans (SMP), and risk-based monitoring strategies.
  • Review monitoring deliverables including site visit reports, monitoring calls, central monitoring outputs, and site communication records.

Patient Safety, Compliance & Data Integrity

  • Ensure clinical study execution maintains the highest standards of:
    • Patient safety
    • Protocol compliance
    • ICH-GCP adherence
    • Country regulatory compliance
    • Data integrity
  • Identify operational risks impacting trial conduct, patient protection, and study quality.
  • Support inspection readiness and compliance governance activities.

Risk Management & Strategic Oversight

  • Lead risk identification, risk assessment, and mitigation planning for assigned clinical programs.
  • Support development and execution of Risk Assessment and Categorization Tool (RACT) activities.
  • Use operational metrics, dashboards, reports, and prior study intelligence to proactively identify delivery risks.
  • Escalate timeline, quality, scope, and budget risks to project leadership as appropriate.

Cross-Functional Collaboration & Global Study Coordination

  • Collaborate closely with:
    • Study Start-Up teams
    • Patient Recruitment teams
    • Data Management teams
    • Medical Monitoring
    • Pharmacovigilance
    • Quality Assurance (QA)
    • Sponsor stakeholders
    • Vendor partners
  • Coordinate operational handoffs to achieve milestones such as:
    • Site activation targets
    • Enrollment goals
    • Data cut deadlines
    • Database lock timelines

Vendor Management & Stakeholder Engagement

  • Manage vendor interactions and third-party delivery coordination where applicable.
  • Act as a key escalation point for investigative sites, CRAs, sponsor teams, and operational stakeholders.
  • Support conflict resolution with sites and stakeholders when required.
  • Vendor management experience is strongly preferred.