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Specialist-Manufacturing Investigations - Major Deviations

10+ years
110,498.00 - 131,829.00
10 Dec. 3, 2024
Job Description
Job Type: Full Time Education: PhD/BSc/MSc/DPharma/PharmD/MBBS/BDS/BAMS/BHMS/MD Skills: Causality Assessment, Clinical SAS Programming, Communication Skills, CPC Certified, GCP guidelines, ICD-10 CM Codes, CPT-Codes, HCPCS Codes, ICD-10 CM, CPT, HCPCS Coding, ICH guidelines, ICSR Case Processing, Interpersonal Skill, Labelling Assessment, MedDRA Coding, Medical Billing, Medical Coding, Medical Terminology, Narrative Writing, Research & Development, Technical Skill, Triage of ICSRs, WHO DD Coding

Job Title: Specialist - Manufacturing Investigations
Location: North Carolina, USA


About Amgen

Amgen is a global leader in biotechnology, dedicated to serving patients battling serious illnesses. With a history of pioneering breakthroughs since 1980, Amgen is transforming the future of healthcare, focusing on four therapeutic areas: Oncology, Inflammation, General Medicine, and Rare Disease. Through our innovative research, manufacturing, and delivery of medicines, we impact the lives of millions of patients worldwide.

Amgen is investing in its FleX Batch facility, the most advanced drug substance manufacturing plant to date. This facility will combine cutting-edge technology, disposable systems, and Industry 4.0 capabilities to provide the flexibility needed for modern operations. It will also incorporate sustainability measures to help achieve Amgen's goal of becoming a carbon-neutral company by 2027.


What You Will Do

As a Specialist - Manufacturing Investigations, you will play a vital role in investigating major deviations in Amgen's North Carolina Biologics Drug Substance Manufacturing plant. Your responsibilities will include:

  • Deviation Investigation Management:
    Lead major investigations by assembling teams, performing root cause analysis, developing CAPAs (Corrective and Preventive Actions), and documenting findings in compliance with industry standards. You will drive continuous improvements in the investigation process.

  • Cross-Functional Leadership:
    Collaborate with teams across Process Development, Facilities & Engineering, Automation, EHSS, and Quality. You will effectively coordinate these teams to ensure timely resolution of deviations.

  • Regulatory & Internal Communication:
    Present your findings to regulatory inspectors, internal auditors, and management. You will also communicate investigation progress clearly to various stakeholders.

  • Problem-Solving & Process Improvements:
    Apply inductive and deductive reasoning to investigate complex issues and implement structured problem-solving approaches. You will also develop tools to track investigation progress and ensure on-time resolution.

  • Learning & Collaboration:
    Encourage collaboration within the team and across departments to maximize the effectiveness of investigations, using strategies such as Operational Learning Teams.


What We Expect of You

We are seeking a collaborative investigator with experience in biologics Drug Substance manufacturing and investigations. The ideal candidate will have strong communication skills, project management experience, and the ability to manage complex investigations. Below are the qualifications we expect:

Basic Qualifications:

  • High School Diploma/GED and 10 years of directly related experience, OR
  • Associate’s Degree and 8 years of directly related experience, OR
  • Bachelor’s Degree and 4 years of directly related experience, OR
  • Master’s Degree and 2 years of directly related experience, OR
  • Doctorate Degree.

Preferred Qualifications:

  • 5+ years of relevant work experience in biotech or pharmaceutical industries, particularly in manufacturing, process development, or quality assurance.
  • Expertise in compliance, root cause analysis (using tools such as 5-whys, fishbone diagrams, Kepner-Tregoe Problem Analysis®, and Design of Experiment), and quality systems.
  • Degree in Science or Engineering.
  • Experience in leading complex investigations and presenting findings during regulatory inspections and internal audits.
  • Proficiency with Veeva QMS for managing deviation investigations and CAPAs.
  • Excellent communication and interpersonal skills with the ability to build relationships across functions.

What You Can Expect from Us

At Amgen, we are committed to both your professional and personal growth. We offer:

  • Opportunities for Development: Learn and grow with us as you advance your career.
  • Collaborative and Inclusive Culture: Join a diverse team where your contributions are valued.
  • Competitive Total Rewards Plan: In addition to your salary, we offer comprehensive benefits that align with industry standards.

Ready to make a difference?
Apply now and join Amgen’s mission to change the world of biotechnology and improve the lives of patients.

Visit careers.amgen.com to apply.


Equal Opportunity Statement
Amgen is an Equal Opportunity Employer. We are committed to creating an inclusive environment and will provide reasonable accommodations to candidates with disabilities throughout the hiring process. Please contact us if you need assistance.