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Scientist - Antibody Optimization (Non- Phd)

6+ years
$74,900.00 to $124,800.00 Per Annum
10 Nov. 23, 2024
Job Description
Job Type: Full Time Education: B.Sc./M.Sc./B.Pharm/M.Pharm/Life science Skills: Causality Assessment, Clinical SAS Programming, Communication Skills, CPC Certified, GCP guidelines, ICD-10 CM Codes, CPT-Codes, HCPCS Codes, ICD-10 CM, CPT, HCPCS Coding, ICH guidelines, ICSR Case Processing, Interpersonal Skill, Labelling Assessment, MedDRA Coding, Medical Billing, Medical Coding, Medical Terminology, Narrative Writing, Research & Development, Technical Skill, Triage of ICSRs, WHO DD Coding

Role Overview: Scientist – Oncology Therapeutics and Drug Discovery

Pfizer is seeking a Scientist to join its Worldwide Research and Development team, focusing on Oncology therapeutics and therapeutic combinations. In this role, you will work at the intersection of early discovery and protein engineering to develop novel biotherapeutics. Your work will involve a range of molecular biology techniques, cell biology, and protein expression, contributing to the development of bispecific antibodies and other drug formats for cancer treatment.

Key Responsibilities:

  1. Experimental Design & Execution:

    • Conduct experiments to evaluate bispecific formats, including cell binding, kinetic assays, internalization, and cytotoxic activity.
    • Work on novel drug combination strategies to enhance cancer treatment efficacy.
    • Develop cell-based assays to support the evaluation of drug candidates.
    • Perform protein/antibody expression and purification, as well as biophysical characterization.
  2. Data Analysis & Reporting:

    • Analyze experimental data and generate clear, detailed reports that can be shared with cross-functional teams.
    • Collaborate with other scientists and computational biologists to integrate findings and drive project progression.
  3. Team Collaboration & Influence:

    • Work as part of a cross-disciplinary team, contributing scientific judgment to influence project goals and strategies.
    • Effectively communicate your findings and ideas to other team members.
  4. Safety & Quality Compliance:

    • Adhere to safety protocols and standard laboratory procedures while maintaining attention to detail and handling shifting priorities and timelines.

Qualifications:

Must-Have:

  • Bachelor’s degree with 6+ years of experience in molecular biology and mammalian cell culture techniques.
  • Experience in implementing and executing novel drug combination strategies.
  • Strong interest in computational biology and bioinformatics.
  • Ability to collaborate with diverse teams and communicate scientific findings effectively.

Nice-to-Have:

  • Master’s degree with 4+ years of relevant experience.
  • Experience working with antibodies, including bispecific formats and antibody-drug conjugates (ADCs).
  • Familiarity with gene editing or screening methodologies.
  • Understanding of phage or yeast display technologies.

Physical/Mental Requirements:

  • Ability to perform laboratory tests and complex data analysis.
  • Strong attention to detail and ability to prioritize tasks.

Non-Standard Work Schedule/Travel:

  • Occasional travel for conferences or training (domestic and international).

Compensation and Benefits:

  • Base Salary: $74,900 to $124,800 annually.
  • Bonus: Eligible for Pfizer’s Global Performance Plan with a bonus target of 7.5% of the base salary.
  • Benefits: Includes a 401(k) plan, paid leave, medical, dental, and vision coverage, and more.

Other Information:

  • Work Location: On-premise.
  • Relocation Assistance: Available based on business needs or eligibility.
  • EEO Statement: Pfizer is an equal opportunity employer, committed to diversity and inclusion.

Deadline to Apply:

  • December 6, 2024

This role offers an exciting opportunity to contribute to groundbreaking oncology therapeutics at Pfizer, supporting both cutting-edge research and the development of innovative therapies to change patients' lives.