Research (Scientific) Associate Director, Computational Chemistry

6+ years

149,100.00 - 234,300.00

Boston

10 Dec. 31, 2024

Job Description

Job Type: Full Time Education: PhD Skills: Causality Assessment, Clinical SAS Programming, Communication Skills, CPC Certified, GCP guidelines, ICD-10 CM Codes, CPT-Codes, HCPCS Codes, ICD-10 CM, CPT, HCPCS Coding, ICH guidelines, ICSR Case Processing, Interpersonal Skill, Labelling Assessment, MedDRA Coding, Medical Billing, Medical Coding, Medical Terminology, Narrative Writing, Research & Development, Technical Skill, Triage of ICSRs, WHO DD Coding

The job description you provided is for a Computational Chemistry Leader at Takeda, located in Boston, Massachusetts. This position is designed for an experienced individual in computational chemistry to contribute to drug discovery projects across various modalities. Below is a summary of the key details:

Key Responsibilities:

Computational Expertise:
- Lead computational chemistry efforts within a multi-disciplinary drug discovery team, providing technical expertise to advance drug discovery across different modalities (e.g., small molecules, peptides, RNA/oligonucleotides, biologics).
- Develop, validate, and implement innovative computational approaches to improve research productivity and success.
- Contribute computational strategies to inform decisions related to compound design, potency, selectivity, and improving ADME/Tox (absorption, distribution, metabolism, excretion, and toxicity) endpoints.
Team Leadership:
- Build and lead a team of computational chemists, driving high productivity levels.
- Provide leadership within a multidisciplinary team, ensuring effective decision-making and fostering collaboration across various scientific disciplines.
Drug Discovery:
- Work on progressing drug discovery projects from hits to clinical leads.
- Provide key input into project teams, influencing and prioritizing compound designs based on computational strategies.
- Integrate emerging AI methods, machine learning, and other advanced computational chemistry techniques into the drug discovery process.
Technical Proficiency:
- Utilize a variety of computational tools and methodologies, including molecular docking, virtual screening, molecular dynamics, quantum mechanics, cheminformatics, machine learning, and data mining.
- Stay updated on the latest computational chemistry tools and software, ensuring the application of cutting-edge technologies in drug discovery.
External Networking:
- Network with renowned researchers in computational chemistry and AI to stay at the forefront of innovations in drug discovery.

Qualifications:

Education: PhD in a relevant scientific discipline.
Experience:
- A minimum of 6 years of industry experience in pharma or biotech, specifically in drug discovery.
- Demonstrated impact in progressing drug discovery projects, from hit identification to clinical leads.
- Extensive experience with computational chemistry tools and techniques, and proficiency in using state-of-the-art software for drug discovery.
- Experience integrating machine learning and AI methods into computational chemistry workflows.

Skills:

Expertise in computational chemistry principles and their application in drug discovery.
Leadership capabilities in managing and building high-performing teams.
Strong communication skills, able to present complex computational strategies to cross-functional teams.
Ability to influence project decision-making with scientific and technical insights.

Compensation and Benefits:

Salary Range: $149,100 - $234,300 (based on qualifications and experience).
Benefits: Medical, dental, and vision insurance, 401(k) with company match, paid vacation, sick time, tuition reimbursement, wellness benefits, and more.

About Takeda:

Takeda is a global biopharmaceutical company focused on delivering life-changing therapies. The company emphasizes fostering a diverse and inclusive workforce and encourages a culture of lifelong learning and career growth. Takeda strives for excellence and is committed to improving the health of people around the world.

This position offers an exciting opportunity to work with cutting-edge computational methods in drug discovery while contributing to Takeda's mission of transforming patient care.

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Research (Scientific) Associate Director, Computational Chemistry

Job Description

Key Responsibilities:

Qualifications:

Skills:

Compensation and Benefits:

About Takeda:

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